A5037037837- Chemotherapy-induced cardiotoxicity and mitigation
- Breast Cancer Treatment Studies
- Vascular Tumors and Angiosarcomas
- Cardiac tumors and thrombi
- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- Ultrasound and Hyperthermia Applications
- Heart Failure Treatment and Management
- Ultrasound in Clinical Applications
- Effects of Radiation Exposure
- Advances in Oncology and Radiotherapy
- Neuroblastoma Research and Treatments
- Occupational and environmental lung diseases
- Medical Imaging and Pathology Studies
- Cardiac Imaging and Diagnostics
- Carcinogens and Genotoxicity Assessment
- Glioma Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Hepatocellular Carcinoma Treatment and Prognosis
- Acute Myocardial Infarction Research
- Cutaneous lymphoproliferative disorders research
- Radiation Therapy and Dosimetry
- DNA Repair Mechanisms
University of Bari Aldo Moro
2014-2019
Ospedale A. Perrino
2010-2018
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2015
University Radiology
2014
To analyze temporal changes of B-type natriuretic peptide (BNP) used as index heart remodeling in left-sided breast cancer patients after radiotherapy (RT) and its relationship with dosimetric parameters.BNP dose-volume parameters for ventricle were collected 59 (median age 58.0 years) during a 1-year follow-up. Biochemical measurements performed before the RT treatment (T0), at 15 days (T(15day)), end (T(endRT)), then 1, 3, 6, 9, 12 months (T1, T3, T6, T9 T12). A logistical regression...
Genetic predisposition has been shown to affect the severity of skin complications in breast cancer patients after radiotherapy. Limited data exist regarding use a genetic risk score (GRS) for predicting tissue radiosensitivity. We evaluated impact different single-nucleotide polymorphisms (SNPs) genes related DNA repair mechanisms and oxidative stress response combined GRS on acute adverse effects induced by radiation therapy (RT). Skin toxicity was scored according Radiation Therapy...
Epithelioid hemangioendothelioma is a rare vascular tumor that has an epithelioid and histiocytoid appearance, originates from endothelial or pre-endothelial cells comprises less than 1% of all tumors. It was described for the first time in 1975 as pulmonary hemangioendothelioma, because initially it believed to be aggressive form bronchoalveolar cell carcinoma with remarkable propensity invade adjacent blood vessels small airways. Only few cases have been reported literature date. Tumor...
Left-sided breast cancer patients treated with radiotherapy (RT) are at risk for late radiation-induced cardiovascular complications.The aim of this study was to investigate the BNP plasma levels in long-term survivors who received only RT as well assess whether cardiac dose associated values.Plasma samples measurement were repeated 29 (63 ± 11 years) alive 5 years after radiotherapy, free heart disease and available provide new blood sample. All had measurements baseline. The ΔBNP measured...
Background and Purpose Breast cancer patients exposed to doses of radiation after radiotherapy could develop toxicity lung. Lung ultrasound ( LUS ) is able detect interstitial lung disease by the evaluation B‐lines. The aim our study was assess number B‐lines diagnose involvement chest radiotherapy. Materials Methods We measured in treated contralateral 20 breast patients, 1–3 months end 1 year previous . sum 72 sites on anterior posterior yielded a global score. Results were more numerous...
Radiation therapy (RT) for breast cancer after conservative surgery can be life-saving but remains associated with significant late side effects, including lung fibrosis, detected by chest CT. Aim of this study was to assess whether ultrasound (LUS) may detect fibrosis through the biomarker B-lines.We evaluated 30 women (median age 67 years, range 46-80 years) about 3-8 years RT (follow up 38-101 months, median 58 months) left (n = 12) or right 18) (stage 1, n 24; stage 2, 6), treated total...
The general issue seems to be that, when bone or pulmonary lesions are small and limited in number, surgical, curative resection (that is amputation, en-bloc resection, wedge resection) achieves good outcomes.