A5010451675- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
- Frailty in Older Adults
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer, Lipids, and Metabolism
- Head and Neck Cancer Studies
- Genetic factors in colorectal cancer
- Cancer Diagnosis and Treatment
- Dysphagia Assessment and Management
- Lymphoma Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Esophageal and GI Pathology
- Anorectal Disease Treatments and Outcomes
- Stoma care and complications
- Esophageal Cancer Research and Treatment
- Intensive Care Unit Cognitive Disorders
- Multiple and Secondary Primary Cancers
- Cancer Risks and Factors
Chang Gung University
2001-2025
Chang Gung Memorial Hospital
2004-2025
Linkou Chang Gung Memorial Hospital
2018-2024
Memorial Hospital of South Bend
2010-2024
Taipei Municipal YangMing Hospital
2022
Mackay Memorial Hospital
2021
Postoperative delirium (POD) is a common surgical complication in elderly patients. As frailty relatively novel concept, its clinical significance for POD has seldom been examined. This study aimed to investigate the association between and aged cancer patients undergoing elective abdominal surgery Taiwan.We prospectively enrolled 345 consecutive ≥65 years with newly diagnosed who underwent 2016 2018. Frailty assessment was performed using Comprehensive Geriatric Assessment (CGA). assessed...
Abstract Background Approximately 20% of patients with colorectal cancer are initially diagnosed stage IV disease. This study aims to examine the role regional lymph node (LN) status in metastatic (mCRC) respect clinicopathologic features and survival outcomes. Methods We investigated 1147 mCRC had undergone surgical resection primary CRC. A total 167 were placed LN-negative (LN−) group another 980 LN-positive (LN+) group. Results LN+ exhibited a significantly higher rate T4 tumors (p =...
Background Whether the prevalence of frailty and its clinical significance are relevant to treatment outcomes in younger (aged < 65 years) cancer patients remains uncertain. This study aimed evaluate impact on with head neck esophageal malignancy. Material methods multicenter prospective recruited 502 locally advanced during 2016–2017 Taiwan, aged 20–64 years who received curative-intent concurrent chemoradiotherapy (CCRT) as first-line antitumor treatment. Baseline assessment using...
Frailty is common in older patients with cancer; however, its clinical impact on the survival outcomes has seldom been examined these patients. This study aimed to investigate association of frailty and surgical complications cancer after elective abdominal surgery Taiwan.
Postoperative delirium (POD) is a common complication in older adults, with unknown epidemiology and effects on surgical outcomes Asian geriatric cancer patients. This study evaluated incidence, risk factors, association between adverse POD after intra-abdominal surgery Taiwan.Overall, 345 patients aged ≥65 years who underwent elective abdominal at medical center Taiwan were prospectively enrolled. Delirium was assessed daily using the Confusion Assessment Method. Univariate multivariate...
BACKGROUND /AIMS: The aim of this study was to calculate the prevalence elevated carcinoembryonic antigen (CEA) among colorectal cancer (CRC) patients and evaluate prognostic value preoperative serum CEA levels in them.Between 1995 2005, 8,861 consecutive were enrolled from a prospective database. =5ng/mL defined as CEA.In multivariate analysis, correlated with higher ages, circumferential tumors, colon large liver metastasis high-stage (AJCC) tumors. After 44-month median follow-up, found...
Abstract Background Local excision (LE) is a feasible treatment approach for rectal cancers in stage pT1 and presents low pathological risk, whereas total mesorectal (TME) reasonable more advanced cancers. On the basis of pathology findings, surgeons may suggest TME patients receiving LE. This study compared survival outcomes between LE with/without chemoradiation mid cancer pT1/pT2, with highly selective intermediate risk. Methods retrospective included 134 who received 39 underwent risk...
Linked-color imaging (LCI) is a recently developed system used in endoscopy. It creates clear and bright endoscopic images using short-wavelength, narrow-band laser light combined with white light. The illuminating signal processing emphasize slight color differences abnormal regions that approximate the normal of mucosa. As result, initially appearing red become deeper shade red, while originally brighter, yet natural tones. This process facilitates recognition mucosa clarifies boundaries...
Colorectal cancer is the leading cause of cancer-related deaths worldwide, and early detection has proven to be an effective method for reducing mortality. The machine learning can implemented build a noninvasive stratifying tool that helps identify patients with potential colorectal precancerous lesions (polyps). This study aimed develop risk-stratified polyps in asymptomatic, healthy participants. A total 20,129 consecutive asymptomatic who underwent health checkup between January 2005...
Background/Aim: The clinical significance of frailty status on treatment outcome in patients with esophageal cancer (EC) has been seldom explored. This study aimed to evaluate the impact pretreatment treatment-related toxicity and survival EC undergoing concurrent chemoradiotherapy (CCRT). Patients Methods: aged ≥20 years newly diagnosed locally advanced receiving neoadjuvant radiotherapy chemotherapy weekly administration carboplatin paclitaxel for 5 weeks were prospectively enrolled. A...
The implications of extracellular nicotinamide phosphoribosyltransferase (eNAMPT), a cancer metabokine, in colonic polyps remain uncertain.A 2-year prospective cohort study patients who underwent colonoscopy was conducted. Biochemical parameters and serum eNAMPT levels were analyzed at baseline every 24 weeks postpolypectomy. NAMPT-associated single-nucleotide polymorphisms (SNPs), including rs61330082, rs2302559, rs10953502, rs23058539, assayed.Of 532 patients, 80 (15%) had prominent...
Abstract Routine postoperative surveillance is recommended for the patients with colorectal cancer (CRC). This study aimed to clarify conditions indicate initial suspicion of CRC recurrence in different preoperative serum carcinoembryonic antigen (CEA) level groups, including positive physical signs/symptoms, elevated CEA level, radiologic studies results, and other tumor markers. A total 2268 after curative surgery were enrolled this study. The classified into 3 groups according (low, <2...
Purpose: Being elevated body mass index (BMI) has been considered a poor prognostic factor in patients with cancer.However, studies about the impact of BMI on survival outcome after cancer surgery have conflicting results.This study aimed to evaluate long-term postoperative large cohort Asian population solid cancers.Methods: A total 33,551 who underwent curative-intent for cancers between January 2007 and December 2012 at four hospitals Taiwan were included.BMI was analyzed using univariate...
Impaired kidney function is associated with different diseases. However, its impact on colorectal cancer has not been clarified. In order to understand the effect of preoperative outcome patients cancer, we analyzed localized or regional diseases.In total, 3731 stage I III (CRC) were in Chang Gung Memorial Hospital. Modification Diet Renal Disease (MDRD) formula was used for estimated glomerular filtration rate (eGFR). Receiver operating characteristic (ROC) analysis cut-off value;...
(1) Background: The aim of this study was to develop a prediction model for assessing individual mPC risk in patients with pT4 colon cancer. Methods: A total 2003 cancer undergoing R0 resection were categorized into the training or testing set. Based on set, 2044 Cox models developed. Next, maximal C-index and minimal error selected. final then validated based set using time-dependent area under curve Brier score, scoring system Patients stratified high- low-risk group by their cut-off...
9606 Background: Serum squamous cell carcinoma antigen (SCC-Ag) elevation without detectable recurrent lesion during follow-up in cervical cancer patients presents a diagnostic and therapeutic challenge. We evaluated fluorine-18-labeled fluoro-2-deoxy-D-glucose positron emission tomography (PET) this situation by prospective trial. Methods: Women with cancer, having completely responded to primary or salvage treatment, had serum SCC-Ag >= 2.0 ng/ml two consecutive measures no evidence of...
Purpose. In this study, we compared the rectal cancer patients with and without preoperative radiotherapy, to evaluate change of pathologic characteristics prognosis. Patients Methods. From 2002 2007, cases primary receiving curative resection were selected. Totally, there 1544 including 239 radiotherapy enrolled. Results. After significant included more percentage smaller tumor size, ulcerative morphologic type poor differentiation histological grade in RT than those not (all p ＜ 0.05). The...
Various neurocognitive tests have shown that cycling enhances cognitive performance compared to resting. Event-related potentials (ERPs) elicited by an oddball or flanker task clarified the impact of dual-task on perception and attention. In this study, we investigate effect recruitment during tasks involve not only stimulus identification but also semantic processing memory retention. We recruited 24 healthy young adults (12 males, 12 females; mean age = 22.71, SD 1.97 years) perform three...