A5011017325- Spectroscopy Techniques in Biomedical and Chemical Research
- Quantum optics and atomic interactions
- Spectroscopy and Quantum Chemical Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Quantum Information and Cryptography
- SARS-CoV-2 and COVID-19 Research
- Laser-Matter Interactions and Applications
- Photonic and Optical Devices
- SARS-CoV-2 detection and testing
- Spectroscopy and Chemometric Analyses
- Spectroscopy and Laser Applications
- Plasmonic and Surface Plasmon Research
- Advanced Fiber Laser Technologies
- Quantum Mechanics and Applications
- Advanced Biosensing Techniques and Applications
- Random lasers and scattering media
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Advanced Optical Sensing Technologies
- Optical Coherence Tomography Applications
- Strong Light-Matter Interactions
- Quantum Computing Algorithms and Architecture
- Advanced Fluorescence Microscopy Techniques
- Advanced Fiber Optic Sensors
- Magnetic Bearings and Levitation Dynamics
Texas A&M University
2016-2025
Mitchell Institute
2024
Quantum Applied Science and Research (United States)
2024
Bridge University
2021
Princeton University
2021
Baylor University
2021
Tsinghua University
2009-2012
The COVID-19 pandemic has profoundly impacted global economies and healthcare systems, revealing critical vulnerabilities in both. In response, our study introduces a groundbreaking method for the detection of SARS-CoV-2 cDNA, leveraging Luminescence resonance energy transfer (LRET) between upconversion nanoparticles (UCNPs) gold (AuNPs) to achieve an unprecedented limit 242 femtomolar (fM). This innovative sensing platform utilizes UCNPs conjugated with one primer AuNPs another, targeting...
Photonic integrated circuits (PICs) are vital for developing affordable, high-performance optoelectronic devices that can be manufactured at an industrial scale, driving innovation and efficiency in various applications. Optical loss of modes thin film waveguides is a critical measure their performance. Thin films growth, lithography, masking, etching processes imperfect introduce significant sidewall top-surface roughness cause dominating optical losses photonic structures. These as...
Tip-enhanced Raman spectroscopy (TERS) enables nanoscale chemical mapping of biological structures, providing high-resolution, high-signal-to-noise ratio imaging into molecular distribution and interactions beyond the capabilities conventional imaging. However, challenges such as deformation fragile cells complexity signal interpretation would increase difficulty in investigating samples with TERS. Here, we demonstrate using TERS to investigate cell wall heterogeneity Aspergillus fumigatus...
Lateral flow assay (LFA) has long been used as a biomarker detection technique. It advantages such low cost, rapid readout, portability, and ease of use. However, its qualitative readout process lack sensitivity are limiting factors. We report photon-counting approach to accurately quantify LFAs while enhancing sensitivity. In particular, we demonstrate that the density SARS-CoV-2 antibodies can be quantified measured with an enhanced using this simple laser optical analysis.
Significance Surface features of a virus are very important in determining its virility. For example, the spike protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to ACE2 receptor site host cell with much stronger affinity than did original SARS virus. Thus, it is clearly understand virion surface structure. To that end, present paper combines spatial resolution atomic force microscopy and spectral coherent Raman spectroscopy. This combination tip-enhanced using...
Raman spectroscopy is a powerful tool for molecular chemical analysis and bioimaging, which shows an astonishing sensitivity when combined with huge enhancement by the coherence surface effects. Noble metal nanoparticles have been commonly used spontaneous surface-enhanced scattering (SERS) coherent anti-Stokes (SECARS) spectroscopies, as they provide large factors via electromagnetic mechanisms. Recently, two-dimensional (2D) semiconductors, such monolayer molybdenum disulfide (MoS2), were...
Molecular polaritons created by the strong coupling between matter and field in microcavities enable control of molecular dynamical processes optical response. Multidimensional infrared spectroscopy is proposed for monitoring polariton-assisted cooperative properties. The response molecules to local fluctuations incorporated full dynamics monitored through time- frequency-resolved multidimensional signal. cooperativity against solvent-induced disorder its connection localization vibrational...
In a viral pandemic, few important tests are required for successful containment of the virus and reduction in severity infection. Among those tests, test neutralizing ability an antibody is crucial assessment population immunity gained through vaccination, to therapeutic value antibodies made counter infections. Here, we report sensitive technique detect relative strength various against SARS-CoV-2 virus. We used bright, photostable, background-free, fluorescent upconversion nanoparticles...
Optical imaging through scattering media is a long-standing challenge. Although many approaches have been developed to focus light or image objects media, they are either invasive, restricted stationary slowly-moving require high-resolution cameras and complex algorithms retrieve the images. Here we introduce computational technique that can overcome these restrictions by exploiting spatial-temporal encoded patterns (STEP). We present non-invasive with single-pixel photodetector. show method...
Development of a simple, label-free screening technique capable precisely and directly sensing interaction-in-solution over size range from small molecules to large proteins such as antibodies could offer an important tool for researchers pharmaceutical companies in the field drug development. In this work, we present thermostable Raman interaction profiling (TRIP) that facilitates low-concentration low-dose binding between protein ligand physiologically relevant conditions. TRIP was applied...
In this Letter we present a new technique for attaining efficient low-background coherent Raman scattering where the coherence is mediated by tunable infrared laser in two-photon resonance with chosen vibrational transition. addition to traditional benefits of conventional schemes, approach offers number advantages including potentially higher emission intensity, reduction nonresonant four-wave mixing background, preferential excitation anti-Stokes field, and simplified phase matching...
Strong quantum correlated sources are essential but delicate resources for information science and engineering protocols. Decoherence loss the two main disruptive processes that lead to of nonclassical behavior in correlations. In systems, scattering can contribute both decoherence loss. this work, we present an experimental scheme capable significantly mitigating adverse impact systems. Our system is composed a two-mode squeezed light generated with four-wave-mixing process hot rubidium...
Abstract Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get more accurate picture of virus’ spread.” We have been involved with biopathogen detection since 2001 anthrax attacks were first detect real-time. A variation laser spectroscopic techniques we developed for rapid can be applied Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2...
We study backward cooperative emissions from a dense sodium atomic vapor. Ultrashort pulses produced conventional amplified femtosecond laser system with an optical parametric amplifier are used to excite atoms resonantly on the two-photon 3S–4S transition. Backward superfluorescent (BSFEs), both 4S–3P and transitions, observed. The picosecond temporal characteristics of BSFE observed using ultrafast streak camera. power laws for dependencies average time delay intensity BSFEs input analyzed...
Native pollinators are crucial to local ecosystems but under threat with the introduction of managed pollinators, e.g., honeybees (Apis mellifera). We explored feasibility employing entomological lidar technique in native pollinator abundance studies. This study included individuals both genders three common solitary bee species, Osmia californica, lignaria, and ribifloris, North America. Properties including optical cross-section, degree linear polarization, wingbeat power spectra at all...
We examine the concentration dependence of Coherent Anti-Stokes Raman Scattering (CARS) signal obtained for gas mixtures at various conditions using Femtosecond Adaptive Spectroscopic Technique (FAST). use CARS Q-branch vibrational oscillation molecular oxygen (1556 cm−1) to confirm quadratic coherent on number molecules in a test volume. In addition, we demonstrate multi-shot FAST imaging flow free space by raster-scanning area interest.
Faithful long-distance quantum teleportation necessitates prior entanglement distribution between two communicated locations. The particle carrying on the unknown information is then combined with one of entangled states for Bell-state measurements, which leads to a transfer original onto other states. However in most implemented experiments nowadays, measurements are performed even before successful entanglement. This an instant collapse state transmitted particle, actually single-particle...
One of the important nonclassical effects in quantum optics is anti-bunching, which has been observed a large class physical systems - including light-harvesting antennas with cyclic structures. The units ring couple adjacent ones through dipole-dipole interactions. We show how this strong interaction leads to photon-blockade resulting suppression double excitation pathway and anti-bunching photosynthesis systems. robustness photon blockade demonstrated against disorder hypothesis that...
Faithful transmission of quantum information is a crucial ingredient in communication networks. To overcome the unavoidable decoherence noisy channel, to date, many efforts have been made transmit one state by consuming large numbers time-synchronized ancilla states. However, such huge demands resources are hard meet with current technology and this restricts practical applications. Here we experimentally demonstrate error detection, an economical approach reliably protecting qubit against...
We investigate the excited-state dynamics of hydrogen (H) atoms in flames by using a femtosecond (fs) pump-probe scheme and measuring directional emission signals. An approximately 100-fs pump pulse at 205.1 nm excites H through two-photon process (n = 3 ←← n 1), which is followed detection forward signals induced broadband fs probe near 656 nm. Above certain threshold, we observe quadratic dependence signal on laser energy. Moreover, linewidth varies with delay This behavior can be...