- Salivary Gland Disorders and Functions
- Tribology and Lubrication Engineering
- Advanced Surface Polishing Techniques
- Cephalopods and Marine Biology
- Pediatric health and respiratory diseases
- Pharmacological Receptor Mechanisms and Effects
- Congenital Heart Disease Studies
- Temporomandibular Joint Disorders
- Adhesion, Friction, and Surface Interactions
- Advanced Machining and Optimization Techniques
- Neuropeptides and Animal Physiology
- Marine and fisheries research
- Osteoarthritis Treatment and Mechanisms
- Ion Channels and Receptors
- Adenosine and Purinergic Signaling
- Soft tissue tumor case studies
- Cardiovascular Conditions and Treatments
- Biopolymer Synthesis and Applications
- Vitamin K Research Studies
- Iron Metabolism and Disorders
- Photosynthetic Processes and Mechanisms
- Medical and Biological Ozone Research
- Venomous Animal Envenomation and Studies
- Wireless Power Transfer Systems
- Medical Imaging Techniques and Applications
Keio University
2000-2021
Futaba (Japan)
2003-2020
Shionogi (Japan)
1988-2020
Koto Hospital
2019
Osaka Dental University
2016-2019
Seirei Hamamatsu General Hospital
2016
The University of Tokyo
2012
Tokyo University of Science
2012
National Institute for Basic Biology
2003
Nissin Kogyo (Japan)
2000-2002
A possibility that interferon may potentiate the cytotoxic effects of anticancer drugs or 60Co gamma ray on human neoplastic cells was studied by in vitro and vivo experimental procedures. The used were HeLa (uterine cervical cancer) WI-38 CT-1 (embryonic lung fibroblasts transformed culture ray) cells. As normal cells, used. Interferon a preparation β-type produced fibroblasts. cytotoxicity determined colony formation for experiments tumor growth animal experiments. Of 17 drugs, six namely,...
Phase I clinical studies of 7432‐S, a new oral cephalosporin, including randomized placebo‐controlled trial were conducted with 40 healthy volunteers, in single‐dose studies, 7432‐S was orally administered at doses 25, 50, 100, and 200 mg. The mean plasma levels peaked 2.1 to 3.0 hours reached 1.9, 3.6, 5.6, 11.6 μg/ml, respectively. Linear correlation observed between AUC values given. half‐lives the 0.88 2.26 1.53 ± 0.33 hours. urinary recoveries 67.5 75.2% dose within 24 partially...
Analytic approaches of thermal stress in plastic-encapslated ICs reliability have been studied using a simple, 2-dimensional model the cross section by finite-element method. To test validity model, actual within silicon chip was measured piezoresistive devices. The calculated agreed with experimental values. distributions were changed lead-frame properties. Package cracking, and delamination between molding plastic qualitatively explained. We estimated effect properties on quantitatively....
We studied the effect of lithium addition to neuroleptic treatment in chronic schizophrenia, for which contradictory results have been produced previous studies. Twenty‐one schizophrenic inpatients received a study with randomized, double‐blind, placebo‐controlled, cross‐over design consisting 8 weeks each capsules and identical placebo capsules. The total Brief Psychiatric Rating Scale (BPRS) scores at week were improved significantly compared those treatment. Of BPRS subscales, however,...
The patient was a 101-year-old woman whose chief complaints were difficulty of breathing and high fever. history the present illness included paroxysmal atrial flutter which untreated, but she had not developed heart failure.At admission, auscultation chest revealed moist rales systolic murmur did clearly show presence fixed splitting S2. X-ray examination showed cardiothoracic ratio 61%, moderate bilateral pulmonary congestion, pleural fluid, enlarged arteries. Electrocardiogram with rate...
The solid solution of silver containing 0.42∼2.09 at%Ga was cold-worked and internally oxidized at temperatures between 500 650°C in still air for viarious times. effects oxidation temperature, time solute content on the growth layer were investigated. product solubility N0(s) diffusivity D0 oxygen, activation energy N0(s)D0 calculated by Wagner’s equation.The results summarized as follows.(1) relation depth zone can be expressed a parabolic law. It concluded that internal governed diffusion...
Study background: The objective of study is a survey to report the prevalence burning mouth syndrome (BMS) and evaluated co-morbidities associated BMS. Subjects Methods: A total 393 patients (54 males 339 females; mean age 67 years; range 27-102) were selected for this study. We carried out initial screening blood tests these patients. Furthermore, we examined if there previous and/or present systemic diseases regularly taken medication by medical interview. Results: Female over 50 years old...
Dose volume histogram (DVH) is one of the methods for evaluating feasibility radiotherapy plans. It difficult to thoroughly comprehend an evaluation each plan at a glance and give concise presentation case conference. In this study, we provide useful program that will fulfill such purpose on clinical setting. We have revised our protocols planning, developed using Visual Basic 2010, which could facilitate DVH, used it checking plans Since DVH analysis shows result in simple way, as “OK...