A5056768863- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Regulation of Appetite and Obesity
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Delphi Technique in Research
- Mercury impact and mitigation studies
- Nutrition and Health in Aging
- Medical Malpractice and Liability Issues
- Isotope Analysis in Ecology
- Inhalation and Respiratory Drug Delivery
- Family and Patient Care in Intensive Care Units
- Health, psychology, and well-being
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Marine animal studies overview
- Neurotransmitter Receptor Influence on Behavior
- Photochromic and Fluorescence Chemistry
- Pharmaceutical studies and practices
- Health Policy Implementation Science
- Advanced Chemical Sensor Technologies
- COVID-19 and Mental Health
- Cancer, Stress, Anesthesia, and Immune Response
- Food Allergy and Anaphylaxis Research
National University of Distance Education
2022
European Federation of Allergy and Airways Diseases Patients Associations
2020
Florida Gulf Coast University
2017-2018
University of Hohenheim
2005-2011
Czech Academy of Sciences, Institute of Physiology
2007
Abstract The Grueneberg ganglion (GG) is a cluster of neurones present in the vestibule anterior nasal cavity. Although its function still elusive, recent studies have shown that cells GG transcribe gene encoding olfactory marker protein (OMP) and project their axons to glomeruli bulb, suggesting they may chemosensory function. Chemosensory responsiveness main epithelium (MOE) vomeronasal organ (VNO) based on expression either odorant receptors or putative pheromone receptors. To scrutinize...
The alpha 2-adrenergic receptors have been divided into four pharmacological subtypes, 2A, 2B, 2C, and 2D. OK cell line, a line derived from an opossum kidney, expresses the 2C-adrenergic receptor is prototypical for 2C subtype. cloned human 2C-C4 rat RG10 shown to express pharmacology. Here we report cloning expression of receptor, OKc2. has 64% deduced amino acid identity 21% similarity 2-C4 giving overall 85%. clone, expressed in Chinese hamster ovary cells, pharmacology that correlates...
Adherence is essential for the long-term efficacy of allergen immunotherapy (AIT) and has been evaluated in numerous retrospective studies. However, there are no published guidelines best practice measuring reporting adherence or persistence to AIT, which resulted substantial heterogeneity among existing The 'adherence AIT (APAIT)' checklist developed guide reporting, design interpretation studies that evaluate clinical practice.Five checklists, focussing on study protocol design, use...
The daily impact of chronic obstructive pulmonary disease (COPD) on younger patients is often underappreciated. To assess this, we investigated the burden experienced by and older patients. A panel questions was developed in conjunction with European Federation Allergy Airways Diseases Patients’ Associations Boehringer Ingelheim. online survey conducted Instar Research. Data were collected from eight countries Europe, plus China, Japan United States. All receiving COPD maintenance therapy....
Serotonin (5-hydroxytryptamine or 5-HT) is an important biogenic amine that functions as both a neurotransmitter and hormone in the central nervous system (CNS) periphery. We report here isolation of cDNA from OK cell encodes serotonin receptor (OKc1). When expressed cultured cells, it displayed pharmacological profile negative coupling with adenylyl cyclase characteristic 5-HT1B subtype. Similar to cloned rodent receptors, had high affinity for beta-adrenergic ligand...
Home respiratory therapies (HRT) are treatments aimed at diseases that generally chronic and have a significant impact on the biopsychosocial aspects of patients' lives. No validated patient-reported outcome measures (PROM) experience (PREM) available to assess these quality life (QoL) in HRT. The objective this work was identify validate PROMs PREMs HRT.The process divided into 5 stages: review literature, patient interviews, qualitative validation workshops, cognitive validation,...
To define a set of proposals that would improve the current management chronic obstructive pulmonary disease (COPD) within Spanish National Healthcare System (SNHS) from comprehensive multidisciplinary perspective and to assess impact its implementation clinical, healthcare, economic, social perspectives.A group 20 stakeholders related COPD (healthcare professionals, patients, informal caregivers, among others) participated in an online Delphi process agree on 15 SNHS four areas: diagnosis,...
The 2021 purchase of the respiratory pharmaceutical company Vectura by Phillip Morris International has been criticised public health and medical community, as a conflict interest, with little input to date, from patient community or public. To address this gap, COPD Foundation, along global partners, surveyed 1196 people chronic disease. 70% were bothered tobacco making an inhaler treat lung conditions 48% reported that they would want switch inhalers if knew made sold their devices....
To examine down-estuary effects and how differences in food webs along a salinity gradient might influence mercury (Hg) biomagnification, we conducted study from 2010 to 2015 an estuary with known biological hotspot at its headwaters. Over 907 samples of biota, representing 92 different taxa fish invertebrates, seston sediments were collected the upper, middle lower reach for Hg determination stable nitrogen carbon isotope analyses. Trophic magnification slopes (TMS; log versus δ15N), as...
El sistema sanitario público es el resultado de la interacción factores sociales, económicos, políticos y culturales, en estrecha relación con los valores sociales. Si bien cierto que tiempos recorte pandemia reciente provocada por nuevo coronavirus, COVID-19, se han puesto manifiesto problemas gestión organización sanitaria todo mundo. Uno menos estudiados confianza población hacia sanitario, cuando, realmente, una dimensión fundamental para comprender funcionamiento del mismo. Este...
Objetivo: El objetivo del presente estudio fue realizar una estimación impacto clínico y en el uso de recursos la suspensión visado inspección durante pandemia COVID-19, periodo comprendido entre 1 abril 2021 31 marzo 2022. Metodología: se basa extrapolación un análisis previo realizado por Alcázar-Navarrete et al. 2022 que estudiaron las diferencias clínicas, adherencia resultados salud los pacientes tratados con triple terapia solo dispositivo (SITT) o múltiples dispositivos (MITT). Estos...