- Stroke Rehabilitation and Recovery
- Circular RNAs in diseases
- Legume Nitrogen Fixing Symbiosis
- Cardiac Ischemia and Reperfusion
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Cord Injury Research
- Cancer-related molecular mechanisms research
- Body Image and Dysmorphia Studies
- Plant Molecular Biology Research
- Acute Ischemic Stroke Management
- MicroRNA in disease regulation
- Tattoo and Body Piercing Complications
- Nematode management and characterization studies
- Heart Failure Treatment and Management
- Cassava research and cyanide
- Plant tissue culture and regeneration
- Aesthetic Perception and Analysis
- Enhanced Recovery After Surgery
- Botulinum Toxin and Related Neurological Disorders
- Fashion and Cultural Textiles
- Transcranial Magnetic Stimulation Studies
- Plant Virus Research Studies
- Cardiac Fibrosis and Remodeling
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Plant Reproductive Biology
Jiangsu Province Hospital
2020-2025
Nanjing Medical University
2020-2025
Oil Crops Research Institute
2017-2018
Chinese Academy of Agricultural Sciences
2018
Huazhong Agricultural University
2015
Circular RNAs (circRNAs) arise during pre-mRNA splicing, in which the 3' and 5' ends are linked to each other by a covalent bond. Soybean is an ancient tetraploid, underwent two whole genome duplications. Most of soybean genes paralogous with multiple copies. Although many circRNAs have been identified animals plants, little known about circRNAs, especially derived from genes. Here, we used deep sequencing technology coupled RNase R enrichment strategy bioinformatic approach uncover soybean....
Sucrose non-fermenting-1 (SNF1)-related protein kinase 2s (SnRK2s) that were reported to be involved in the transduction of abscisic acid (ABA) signaling, play important roles response biotic and abiotic stresses plants. Compared systemic investigation SnRK2s Arabidopsis thaliana Oryza sativa, little is known regarding soybean, which one most oil crops. In present study, we performed genome-wide identification characterization GmSnRK2s soybean. summary, 22 identified clustered into four...
Objective: Increasing evidence has uncovered the roles of lncRNA-miRNA-mRNA regulatory networks in cardiovascular diseases. However, crosstalk between ceRNA and development heart failure (HF) remains unclear. This study was to investigate role lncRNA-mediated pathophysiological process HF its potential functions on programmed cell death. Methods: We firstly screened GSE77399, GSE52601 GSE57338 datasets NCBI GEO database for screening differentially expressed lncRNAs, miRNAs mRNAs. based...
Summary Rhg1 (resistance to Heterodera glycines 1) is an important locus that contributes resistance against soybean cyst nematode (SCN; Ichinohe), which the most economically damaging disease of worldwide. Simultaneous overexpression three genes encoding a predicted amino acid transporter, α‐soluble N ‐ethylmaleimide‐sensitive factor attachment protein (α‐SNAP) and wound‐induced resulted in SCN provided by this locus. However, roles two these (excluding α‐ SNAP ) remain unknown. Here, we...
Objectives : N6-methyladenosine (m 6 A) is hypothesized to play a role in the regulation of pathogenesis myocardial infarction (MI). This study was designed compare m A-tagged transcript profiles identify mRNA-specific changes on pathophysiological variations after MI. Methods methylated RNA immunoprecipitation sequencing (MeRIP-seq) and (RNA-seq) were interacted select A-modified mRNAs with samples collected from sham operated MI rat models. A methylation regulated apoptosis/angiogenesis...
Lung cancer surgery is associated with a high incidence of postoperative pulmonary complications (PPCs). Preliminary evidence suggests that ERAS processes can reduce overall PPCs as short- and long-term recovery improved by supporting units to adopt evidence-based care. However, the inconclusive due insufficient high-level studies in this research field. No well-designed, adequately powered, randomized controlled trials (RCTs) have investigated effects rehabilitation based program (PREP) on...
Objective. Muscle weakness and spasticity are common consequences of stroke, leading to a decrease in physical activity. The effective implementation precision rehabilitation requires detailed evaluation. We aimed analyze the surface electromyography (sEMG) signal features elbow flexor muscle (biceps brachii brachioradialis) maximum voluntary isometric contraction (MVIC) fast passive extension (FPE) stroke patients explore main groups that affect active movement muscles provide an objective...
Molecular breeding has become an important approach for crop improvement, and a prerequisite molecular is elucidation of the functions genetic loci or genes. Soybean one most food oil crops worldwide. However, due to difficulty transformation in soybean, studies its functional genomics lag far behind those other such as rice, which severely impairs progress improvement soybean. Here, we describe effective large-scale strategy investigate soybean genes via overexpression full-length cDNA...
This study investigated the functional outcomes of patients with chronic heart failure (CHF) after physiological ischemic training (PIT), identified optimal PIT protocol, evaluated its cardioprotective effects and explored underlying neural mechanisms. Patients CHF were randomly divided into experimental group (n = 25, intervention + regular treatment) control treatment). The included left ventricular ejection fraction (LVEF), brain natriuretic peptide (BNP) cardiopulmonary parameters. LVEF...
Isometric exercise (IE) is a promising intervention of noninvasive revascularization in patients with acute myocardial infarction (AMI). This study aimed to investigate the impact and mechanisms IE training on arteriogenesis AMI. Male Sprague-Dawley rats were randomly assigned into sham-operation group (SO), (MI) group, 13 subgroups treated according intensity, frequency, duration, or monocyte chemoattractant protein-1 (MCP-1), or/and fibroblast growth factor-2 (FGF-2) inhibitors for eight...
Abstract Objective The purpose of this study is to investigate the optimal time window for initiating mobilizing after acute ischemic stroke. Methods TIME Trial a pragmatic, investigator-initiated, multi-center, randomized, 3-arm parallel group, clinical trial. This trial will be conducted in 57 general hospitals mainland China affiliated with Stroke Databank Center and enroll 6033 eligible patients Participants randomly allocated either (1) very early mobilization group which initiated...