A5079573215- Fungal and yeast genetics research
- Antifungal resistance and susceptibility
- Fungal Biology and Applications
- Plant-Microbe Interactions and Immunity
- Polysaccharides and Plant Cell Walls
- Mycorrhizal Fungi and Plant Interactions
- Nematode management and characterization studies
- Mycotoxins in Agriculture and Food
University of Nebraska–Lincoln
2020-2022
Systems of classification are important for guiding research activities and providing a common platform discussion investigation. One such system is assigning microbial taxa to the roles mutualists pathogens. However, there often challenges even inconsistencies in reports findings when display behaviors outside these two static conditions (e.g., commensal). Over last decades, has been some effort highlight continuum symbiosis, wherein certain may exhibit mutualistic or pathogenic traits...
The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress enable wall repair and resumption of normal growth. This complex, interconnected, has been only partially characterized in filamentous fungi. To better understand the dynamic perturbation, a β-glucan synthase inhibitor (micafungin) was added growing
Fungal cell wall receptors relay messages about the state of to nucleus through Cell Wall Integrity Signaling (CWIS) pathway. The ultimate role CWIS pathway is coordinate repair damage and restore normal hyphal growth. Echinocandins such as micafungin represent a class antifungals that trigger by affecting synthesis β-glucans. To obtain better understanding dynamics response its multiple effects, we have coupled dynamic transcriptome analysis with morphological studies Aspergillus nidulans...
The ability to compartmentalize potentially lethal damage via septation appears provide filamentous fungi with a facile means tolerate diverse forms of stress. However, it remains unknown whether this mechanism is deployed in response all stress or limited specific perturbations.
Abstract Fungal cell wall receptors relay messages about the state of to nucleus through Cell Wall Integrity Signaling (CWIS) pathway. The ultimate role CWIS pathway is coordinate repair damage and restore normal hyphal growth. Echinocandins such as micafungin represent a class antifungals that trigger by affecting synthesis β-glucans, filamentous fungi’s response these are fundamentally unknown. To obtain better understanding dynamics its multiple effects, we have coupled dynamic...