A5074693423- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Neuroscience of respiration and sleep
- Acute Kidney Injury Research
- Folate and B Vitamins Research
- Gestational Diabetes Research and Management
- Neonatal Health and Biochemistry
- Pregnancy and preeclampsia studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Urological Disorders and Treatments
- Human Health and Disease
- Congenital Anomalies and Fetal Surgery
- Metabolism and Genetic Disorders
- Retinopathy of Prematurity Studies
- Urologic and reproductive health conditions
- Neonatal and fetal brain pathology
- Biomarkers in Disease Mechanisms
- Congenital heart defects research
- Pediatric Urology and Nephrology Studies
- Cholesterol and Lipid Metabolism
- Regulation of Appetite and Obesity
- Blood groups and transfusion
Medical University of Silesia
2011-2022
University of Silesia in Katowice
2011-2020
University Clinical Centre
2020
Górnośląskie Centrum Medyczne
2001-2005
University of Münster
1995
Abstract Context Standardized description of external genitalia is needed in the assessment children with atypical genitalia. Objectives To validate External Genitalia Score (EGS), to present reference values for preterm and term babies up 24 months correlate obtained scores anogenital distances (AGDs). Design, Setting A European multicenter (n = 8) validation study was conducted from July 2016 2018. Patients Methods EGS based on masculinization score but uses a gradual scale female male...
Acute kidney injury (AKI) is the most common complication of perinatal asphyxia. Recent research indicates that serum neutrophil gelatinase-associated lipocalin (NGAL) an early marker for AKI, but there are lacks data about its use in term neonates with asphyxia.A prospective cohort study was conducted on 43 neonates. Umbilical cord blood and 24 h after birth NGAL, copeptin, creatinine, molality were measured all asphyxiated controls neonates.During period, 8 nenates (18.6 %) suffered from...
Objectives:The aims of this study were: to evaluate the prevalence abdominal wall defects in Polish population, analyze temporal trends prevalence, identify areas (clusters) high risk defects, and characterize, with respect epidemiology, children their mothers area defined as a cluster.Material Methods: We used isolated congenital malformations (gastroschisis Q79.3 omphalocele Q79.2 according International Statistical Classification Diseases Related Health Problems, 10th revision (ICD-10,...
To read the full abstract: J Clin Endocrinol Metab. 2020, Mar 1; 105. doi: https://academic.oup.com/jcem/article-abstract/105/3/e222/5609091?redirectedFrom=fulltext
The aim of the study was to evaluate activin A and NGAL levels as potential early markers perinatal hypoxia.We prospectively studied 58 full-term newborns: 24 with hypoxia (study group) 34 healthy controls. Umbilical cord blood samples were obtained from all subjects immediately after delivery for measurement levels. Both biomarkers correlated biochemical indicators od neonatal complications.Activin significantly higher in hypoxic compared non-hypoxic newborns (0.51 vs. 0.22pg/mL; p<0.01)....
Abstract
Recent reports have revealed increased concentration of neutrophil gelatinase-associated lipocalin (NGAL) in cardiovascular diseases and after episodes hypoxia. We hypothesized that elevated plasma NGAL levels could be a result vascular endothelial injury due to perinatal asphyxia.Ninety-three newborns with gestational age > or = 37 weeks, which 32 were asphyxiated (study group), 61 healthy children (control enrolled the study Serum NGAL, lactate creatinine concentrations, acid-base balance,...
To evaluate activin A as a potential, early marker of perinatal hypoxia and to analyze factors, other than hypoxia, which influence on concentration.Umbilical cord blood samples were collected from 86 newborns with gestational age 30-41. Of the newborns, 26 regarded hypoxic. Activin concentrations measured by means specific two-site enzyme immunoassays. correlated newborns' gender, week gestation, mode delivery gas measurements.Activin levels significantly higher in hypoxic nonhypoxic...
Acute kidney injury (AKI) is a primarily described complication after unbalanced systemic perfusion in neonates with congenital heart defects, including hypoplastic left syndrome (HLHS). The aim of the study was to compare umbilical NGAL concentrations between born HLHS and healthy infants, as well analyze whether determination level could predict AKI prenatally diagnosed HLHS. Twenty-one were enrolled group 30 served controls. Perinatal characteristics postnatal parameters extracted from...
Objectives . The etiology of conotruncal heart defects (CHD) remains unknown; however relation between homocysteine, folate levels, and congenital disease was found. With this perspective in mind, the aim study to investigate biomarkers homosyteine metabolism pathway mothers their neonates with CHD. Material Methods Forty-three pairs CHD forty nonconotruncal (non-CHD) were enrolled. control group (CG) consisted fifty-nine healthy neonates. For estimating plasma total homocysteine (tHcy),...
As the clinical manifestation of neonatal infection is nonspecific and characterised by varied features, it highly problematic to establish an early diagnosis. Recently, hopes have been raised new acute-phase protein-pentraxin 3 (PTX3). PTX3 belongs family long pentraxins, which synthesized in numerous cells like endothelial cells, macrophages, monocytes infiltrating sites inflammation. Material Methods. In our research, we enrolled 29 newborns with as study group 47 healthy ones control...
Wstęp W ostatnich latach obserwuje się stały wzrost zainteresowania ciężarnych alternatywnymi technikami porodu. Metodą, która daje kobiecie możliwość przyjmowania dowolnej pozycji w trakcie porodu, a także zmniejsza częstość epizjotomii i ogranicza stosowanie środków przeciwbólowych oraz rozkurczowych, jest immersja wodna. Technika ta wiąże z lepszą tolerancją bólu u rodzących prowadzi do skrócenia okresów Pomimo tych zalet, istnieją liczne badania kwestionujące korzystny wpływ porodu wody...
Objectives: Holt-Oram syndrome manifests with defects of upper limbs, pectoral girdle and cardiovascular system. The aim this paper was to present complex clinical picture the its variable expression on example family diagnosed genetically neonatal ward, after proband’s prenatal examination. Maretial methods: Nine members were tested for TBX5 gene mutation. Results: Four five had correct genetic test results. diagnosis allowed identify a risk enabled provide them counselling. Conclusions:...
Objectives: In recent years, much attention has been given to infants born prematurely, at 34 0/7 36 6/7 weeks of gestation (WG), which have classified as 'late preterm'. Neonates from that subgroup are less physiologically and metabolically mature than term infants. The aim the study was determine whether 34WG can be preterm' or 'preterm' newborns. Material methods: A total 141 newborns were included in study: 25 ≤ 33WG, 53 late-preterm newborns, 63 Cord-blood neutrophil...
Introduction . Transient tachypnea of the newborn (TTN) is one most common causes respiratory distress in full-term neonates. The diagnosis TTN early postnatal period remains problematic for clinicians, and unfortunately, there exist no reliable diagnostic tests TTN. elevated human epididymis protein 4 (HE4) levels were observed cases severe bronchitis, pneumonia, inflammatory processes. However, little known about fluctuation this biomarker concentrations disorders neonatal period. authors...
Pentraxin 3 (PTX3) is a multifunctional acute phase protein belonging to the family of long pentraxins, which synthesised in numerous cells body under influence proinflammatory factors and locally at site inflammation. Under physiological conditions, PTX3 stored neutrophil granules, where there constant pool glycoproteins. Increased pentraxin levels blood serum are observed as early 1 hour after damaging stimulus. Elevation can be used diagnose fertility disorders women well pregnancy...
Abstract
Hypoplastic left heart syndrome (HLHS) is a rare congenital defect in which the side of severely underdeveloped. Etiology this condition remains unknown. After labour, three-stage cardio-surgical treatment necessary, however all procedures run significant risk complications. Depending on general newborn, first operation – Norwood procedure may be carried out different modifications. Complications are most common after stage palliation, and include morbidities both cardiogenic non-cardiogenic...