A5071709897- Neonatal Respiratory Health Research
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Congenital Diaphragmatic Hernia Studies
- Pregnancy and preeclampsia studies
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Parvovirus B19 Infection Studies
- Fetal and Pediatric Neurological Disorders
- Congenital Heart Disease Studies
- Childhood Cancer Survivors' Quality of Life
- Neonatal and Maternal Infections
- Preterm Birth and Chorioamnionitis
- Neonatal and fetal brain pathology
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Infectious Encephalopathies and Encephalitis
- Anesthesia and Sedative Agents
- Antibiotics Pharmacokinetics and Efficacy
- Infant Nutrition and Health
- Neuroscience of respiration and sleep
- Intestinal Malrotation and Obstruction Disorders
- Urological Disorders and Treatments
- Glycogen Storage Diseases and Myoclonus
- Gestational Trophoblastic Disease Studies
Ghent University Hospital
2012-2024
Universitair Ziekenhuis Brussel
2023
Boston Children's Hospital
1996
Objective. To determine mortality and morbidity at discharge from the hospital of a large population-based cohort infants who were born ≤26 weeks' gestation. Methods. Perinatal data collected on extremely preterm alive onset labor between January 1, 1999, December 31, 2000, in all 19 Belgian perinatal centers. Results. A total 525 recorded. Life-supporting care was provided to 322 liveborn infants, 303 whom admitted for intensive care. The overall survival rate 54%. Of age 7 days, 82%...
Abstract Context Standardized description of external genitalia is needed in the assessment children with atypical genitalia. Objectives To validate External Genitalia Score (EGS), to present reference values for preterm and term babies up 24 months correlate obtained scores anogenital distances (AGDs). Design, Setting A European multicenter (n = 8) validation study was conducted from July 2016 2018. Patients Methods EGS based on masculinization score but uses a gradual scale female male...
Abstract Background White matter change is a well-known abnormality in congenital cytomegalovirus (cCMV) infection, but grading remains challenging and clinical relevance unclear. Objective To investigate if quantitative measurement of white apparent diffusion coefficient (ADC) values magnetic resonance imaging (MRI) the neonatal brain can predict outcome cCMV. Materials methods A retrospective, single-center observational study, including patients with cCMV who had MRI diffusion-weighted...
Investigating the clinical implications of isolated white matter abnormalities on neonatal brain MRI in congenital cytomegalovirus (CMV).Prospective, observational.Two paediatric radiologists, blinded to data, independently scored 286 newborns with CMV. After assessing interobserver variability, mean score was used categorise (normal, doubtful or abnormal). Patients other were excluded.Hearing and neuromotor evaluation.Cohen's weighted kappa 0.79 (95% CI 0.73 0.84). White normal 121...
There is a need for alternative analgosedatives such as dexmedetomidine in neonates. Given the ethical and practical difficulties, protocol design clinical trials neonates should be carefully considered before implementation. Our objective was to identify suitable subsequent evaluation of dosing requirements mechanically ventilated A published paediatric pharmacokinetic model used derive regimen first-in-neonate study. Optimality criteria were applied optimise blood sampling schedule. The...
Congenital cytomegalovirus (cCMV) infection is the leading cause of nonhereditary sensorineural hearing loss in childhood and also associated with CNS abnormalities. The main objective to investigate prognostic value neonatal cranial ultrasound (cUS) magnetic resonance imaging (cMRI) predicting long-term outcome a large cohort cCMV-infected symptomatic asymptomatic patients.Data were prospectively collected from multicentre Flemish registry children cCMV born between 2007 2016. Neonatal cUS...
Cytomegalovirus (CMV) infection is the leading cause of congenital nongenetic sensorineural hearing loss (SNHL) and a major prelingual SNHL that not present at birth. Polymerase chain reaction (PCR) analysis dried blood samples on Guthrie card has been proposed as sensitive specific method to screen for CMV infection.Prospectively, consecutive infants who failed universal neonatal screening children referred noncongenital (NCHL) were included underwent standard audiometric etiologic work-up....
A case of Möbius sequence after exposure to ergotamine during early development is reported. Vascular disruption one the theories explaining pathogenesis sequence. Ergotamine can cause vasospasm and a prolonged marked increase in uterine tone. This second report suggesting relation between maternal ingestion pregnancy subsequent child. (J Child Neurol 2004; 19:398).