- Fungal Biology and Applications
- Mycorrhizal Fungi and Plant Interactions
- Microbial Natural Products and Biosynthesis
- Plant Pathogens and Fungal Diseases
- Microbial Metabolism and Applications
- Plant biochemistry and biosynthesis
- Microbial Metabolic Engineering and Bioproduction
- Fungal and yeast genetics research
- Biocrusts and Microbial Ecology
- Plant Gene Expression Analysis
- Antioxidant Activity and Oxidative Stress
- Algal biology and biofuel production
- Plant tissue culture and regeneration
- Enzyme Production and Characterization
- Ubiquitin and proteasome pathways
- Essential Oils and Antimicrobial Activity
- Tea Polyphenols and Effects
- Infectious Diseases and Mycology
- Photosynthetic Processes and Mechanisms
- Transgenic Plants and Applications
- Enzyme-mediated dye degradation
- Slime Mold and Myxomycetes Research
- Mycotoxins in Agriculture and Food
- Biofuel production and bioconversion
- Enzyme Catalysis and Immobilization
HUN-REN Szegedi Biológiai Kutatóközpont
2020-2025
Institute of Biochemistry
2022-2025
University of Szeged
2008-2019
Hungarian Academy of Sciences
2017
Mucor circinelloides and other members of Mucorales are filamentous fungi, widely used as model organisms in basic applied studies. Although genetic manipulation methods have been described for some Mucoral construction stable integrative transformants by homologous recombination has remained a great challenge these organisms. In the present study, plasmid free CRISPR-Cas9 system was firstly developed modification fungus. The method offers rapid but robust tool to obtain mitotically mutants...
Cre1 is an important transcription factor that regulates carbon catabolite repression (CCR) and widely conserved across fungi. The cre1 gene has been extensively studied in several Ascomycota species, whereas its role expression regulation the Basidiomycota species remains poorly understood. Here, we identified investigated of Coprinopsis cinerea, a basidiomycete model mushroom can efficiently degrade lignocellulosic plant wastes. We used rapid efficient deletion approach based on...
The evolution of multicellularity has been one the major transitions in history life. In contrast to animals and plants, how evolved fungi it compares general principles distilled from study more widely studied model systems, received little attention. This review broadly discusses multicellular functioning fungi. We focus on solved some common challenges associated with multi-celled organisms what unique follow peculiar, filamentous growth form identify discuss seven key for fungal growth:...
Members of the Fusarium solani species complex (FSSC) are most frequently isolated fusaria from soil. Moreover, this solely affects more than 100 plant genera, and is also one major opportunistic human pathogenic filamentous fungi, being responsible for approximately two-third fusariosis cases. Mycotic keratitis due to among leading causes visual impairment blindness in South India, but its management still challenging poor susceptibility isolates conventional antifungal drugs. Aims present...
Abstract Background Precursors of sterols, carotenoids, the prenyl groups several proteins and other terpenoid compounds are synthesised via acetate-mevalonate pathway. One key enzyme this pathway is 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, which catalyses conversion HMG-CoA to mevalonate. reductase therefore affects many biological processes, such as morphogenesis, synthesis different metabolites or adaptation environmental changes. In study, transcription three genes (designated...
The morphogenesis of sexual fruiting bodies fungi is a complex process determined by genetically encoded program. Fruiting reached the highest complexity levels in Agaricomycetes; yet, underlying genetics currently poorly known. In this work, we functionally characterized highly conserved gene termed
Abstract The Agrobacterium ‐mediated transformation was adapted to Backusella lamprospora , a zygomycete fungus closely related Mucor . transforming plasmid contained the hygromycin B resistance ( hph ) and green fluorescent protein gfp genes under control of regulator regions circinelloides gpd1 gene. presence in transformants detected by PCR. introduced could also be amplified directly from spores transformants. efficiency investigated fluorescence microscopy transformed spores. A gradual...
Abstract Sporulation is the most widespread means of reproduction and dispersal in fungi. In Basidiomycota, sexual spores are produced on specialised cells known as basidia, from which they discharged forcibly by a powered process called ballistospory, highest acceleration nature. However, genetics sporulation, particular postmeiotic events related to spore morphogenesis remain poorly known. Here, we explore these processes, based new, highly conserved transcription factor,...
Abstract Fruiting bodies of mushroom-forming fungi (Agaricomycetes) are among the most complex structures produced by fungi. Unlike vegetative hyphae, fruiting grow determinately and follow a genetically encoded developmental program that orchestrates tissue differentiation, growth sexual sporulation. In spite more than century research, our understanding molecular details body morphogenesis is limited general synthesis on genetics this process lacking. paper, we aim to comprehensively...
Zygomycosis is a group of opportunistic fungal infections caused by filamentous fungi belonging in the class Zygomycetes. Incidence such shows an increasing tendency as result widespread use immunosuppressive therapy, intensive cancer chemotherapeutic regimens and broad-spectrum antimicrobial agents. High mortality rates, difficulties their diagnosis intrinsic resistance to most widely used antifungal drugs are characteristic features zygomycoses. All these facts indicate that development...
Mucor piriformis, Gilbertella persicaria and the members of Rhizopus genus (especially R. stolonifer oryzae) are most important agents post-harvest decay among fungi belonging in order Mucorales (Zygomycetes). Epidemiological studies control losses require reproducible methods with which to distinguish characterize isolates. This review summarizes available information regarding genetic physiological variability, strain typing taxonomy this fungal group.