Neha Sahu

ORCID: 0009-0003-6737-7099
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About
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Research Areas
  • Mycorrhizal Fungi and Plant Interactions
  • Fungal Biology and Applications
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Fermentation and Sensory Analysis
  • Fungal and yeast genetics research
  • Genomics and Phylogenetic Studies
  • Phytochemicals and Antioxidant Activities
  • Biocrusts and Microbial Ecology
  • Plant tissue culture and regeneration
  • Plant biochemistry and biosynthesis
  • Microbial Community Ecology and Physiology
  • Natural Antidiabetic Agents Studies
  • Microbial Natural Products and Biosynthesis
  • Plant Taxonomy and Phylogenetics
  • Protist diversity and phylogeny
  • Plant Gene Expression Analysis
  • Natural product bioactivities and synthesis
  • Enzyme-mediated dye degradation
  • Immunotoxicology and immune responses
  • Genomics and Rare Diseases
  • Slime Mold and Myxomycetes Research
  • Sesquiterpenes and Asteraceae Studies
  • Seed and Plant Biochemistry
  • Medicinal Plants and Neuroprotection

HUN-REN Szegedi Biológiai Kutatóközpont
2018-2024

Institute of Biochemistry
2018-2024

Sickle Cell Institute Chhattisgarh, Raipur
2024

Indian Institute of Science Education and Research, Bhopal
2024

University of Szeged
2020-2023

Central Drug Research Institute
2017-2023

Guru Ghasidas Vishwavidyalaya
2023

University of Lucknow
2023

Gautam Buddha University
2022

Father Muller Homoeopathic Medical College
2022

The evolution of complex multicellularity has been one the major transitions in history life. In contrast to simple multicellular aggregates cells, it evolved only a handful lineages, including animals, embryophytes, red and brown algae, fungi. Despite being key step toward organisms, evolutionary origins genetic underpinnings are incompletely known. development fungal fruiting bodies from hyphal thallus represents transition that is inducible under laboratory conditions. We constructed...

10.1073/pnas.1817822116 article EN Proceedings of the National Academy of Sciences 2019-03-22

Fungi are ecologically important heterotrophs that have radiated into most niches on Earth and fulfil key ecological services. Despite intense interest in their origins, major genomic trends of evolutionary route from a unicellular opisthokont ancestor to derived multicellular fungi remain poorly known. Here we provide highly resolved genome-wide catalogue gene family changes across fungal evolution inferred the genomes 123 relatives. We show dominant trend early has been gradual shedding...

10.1038/s41559-023-02095-9 article EN cc-by Nature Ecology & Evolution 2023-06-22

Agaricomycetes are fruiting body-forming fungi that produce some of the most efficient enzyme systems to degrade wood. Despite decades-long interest in their biology, evolution and functional diversity both wood-decay body formation incompletely known. We performed comparative genomic transcriptomic analyses development Auriculariopsis ampla Schizophyllum commune (Schizophyllaceae), species with secondarily simplified morphologies, an enigmatic strategy weak pathogenicity woody plants. The...

10.1111/nph.16032 article EN publisher-specific-oa New Phytologist 2019-07-01

Hypnea musciformis red seaweed is popularly known to produce carrageenan was collected from the Gulf of Mannar, India. Strain HMGM-7 [MTCC 11712] isolated surface this seaweed, which capable producing an extracellular black-coloured polymeric pigment. Based on phenotypic characterization and 16S rDNA sequencing, strain identified as Pseudomonas stutzeri. Biophysical by UV–visible, FT-IR, EPR XRD spectroscopic studies confirmed pigment melanin. Further chemical showed that it acid-resistant,...

10.1111/lam.12111 article EN Letters in Applied Microbiology 2013-06-03

Wood-decaying Basidiomycetes are among the most efficient degraders of plant cell walls, making them key players in forest ecosystems, global carbon cycle, and bio-based industries. Recent insights from -omics data revealed a high functional diversity wood-decay strategies, especially traditional white-rot brown-rot dichotomy. We examined mechanistic bases conifer-specialists Armillaria ostoyae cepistipes using transcriptomic proteomic approaches. spp. (Fungi, Basidiomycota) include...

10.3390/microorganisms9010149 article EN cc-by Microorganisms 2021-01-11

Cre1 is an important transcription factor that regulates carbon catabolite repression (CCR) and widely conserved across fungi. The cre1 gene has been extensively studied in several Ascomycota species, whereas its role expression regulation the Basidiomycota species remains poorly understood. Here, we identified investigated of Coprinopsis cinerea, a basidiomycete model mushroom can efficiently degrade lignocellulosic plant wastes. We used rapid efficient deletion approach based on...

10.1128/aem.00940-22 article EN cc-by Applied and Environmental Microbiology 2022-11-14

Introduction: Diabetes mellitus (DM) is a metabolic disorder that results in glucose accumulation the blood, accompanied by production of advanced glycation end products (AGEs) through cellular proteins. These AGEs interfere with insulin signaling and prevent GLUT4 membrane translocation, thereby promoting more blood causing post-diabetic complications. Methods: In this study, we examine anti-diabetic potential Lyonia ovalifolia (Wall.) Drude, well-known ethnomedicinal plant Indian...

10.3389/fphar.2023.1073327 article EN cc-by Frontiers in Pharmacology 2023-03-27

Shoot tip culture, root organ suspension, and callus culture producing roots were established from shoot tip, hypocotyl segments, respectively, on Murashige Skoog's White's basal media with or without growth regulators. Forskolin was identified by TLC HPLC in 60 days old differentiating 30 micropropagated plants, suspension but not rhizogenic callus. the presence absence of BAP revealed more less similar amounts forskolin as that plants. Root showed traces production.

10.1055/s-2006-961477 article EN Planta Medica 1992-08-01

Callus cultures were established from hypocotyl explants of Cephaelis ipecacuanha, emetine and cephaeline identified by HPLC in callus cultures. The effect macrosalts different basal medium hormones on growth alkaloid accumulation tissues was investigated. Best terms wet/dry weight obtained media containing B5 supplemented with 3% sucrose, 8 mg l-1 IBA, 4 IAA, NAA. highest yields alkaloids detected SH same hormone combination.

10.1055/s-2006-962530 article EN Planta Medica 1988-12-01

Abstract Mushroom-forming fungi (Agaricomycetes) are emerging as pivotal players in several fields, drivers of nutrient cycling, sources novel applications, and the group includes some most morphologically complex multicellular fungi. Genomic data for Agaricomycetes accumulating at a steady pace, however, this is not paralleled by improvements quality genome sequence associated functional gene annotations, which leaves function notoriously poorly understood comparison with other model...

10.1101/2024.05.10.593147 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-05-10

The five different bio-agents viz., Trichoderma viride, T. harzianum, virens, Pseudomonas fluorescens and Bacillus subtilis were evaluated against Pyricularia oryzae at four eight days after incubation through dual culture technique. Among the bio-agents, highest per cent inhibition of mycelial growth fungus was recorded in virens i.e. 67 70 percent respectively with mean 68.5 followed by viride 61 63 62 cent. did not show any P. as pathogen over grew bio-agents.

10.18805/asd.v37i03.8989 article EN Agricultural Science Digest - A Research Journal 2017-08-03

We constructed a reference atlas of mushroom formation based on developmental transcriptome data six species and comparisons >200 whole genomes, to elucidate the core genetic program complex multicellularity fruiting body development in mushroom-forming fungi (Agaricomycetes). Nearly 300 conserved gene families >70 functional groups contained developmentally regulated genes from five species, covering functions related fungal cell wall (FCW) remodeling, targeted protein degradation,...

10.1101/349894 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-06-18

Armillaria ostoyae, a species among the destructive forest pathogens from genus Armillaria, causes root rot disease on woody plants worldwide. Efficient control measures to limit growth and impact of this severe underground pathogen are under investigation. In previous study, new soilborne fungal isolate, Trichoderma atroviride SZMC 24276 (TA), exhibited high antagonistic efficacy, which suggested that it could be utilized as biocontrol agent. The dual culture assay results indicated haploid...

10.1128/spectrum.04626-22 article EN cc-by Microbiology Spectrum 2023-05-04

ABSTRACT Halobacillus sp. strain KGW1 is a moderately halophilic, rod shaped, Gram-positive, yellow pigmented, alkaline protease-producing bacterium isolated from water sample Chilika Lake, Odisha, India. Sequencing of bacterial DNA assembled 3.68-Mb draft genome. The genome annotation analysis showed various gene clusters for tolerance to stress, such as elevated pH, salt concentration, and toxic metals.

10.1128/genomea.00361-16 article EN Genome Announcements 2016-06-30

We report the 4.51 Mb draft genome of Pseudomonas sp. strain BMS12, a Gram-negative bacterium in class Gammaproteobacteria, isolated from rhizospheric sediment Phragmites karka, an invasive weed Chilika Lake, Odisha, India. The BMS12 is capable producing proteases and also efficient plant growth promoter that can be useful for various phytoremedial industrial applications.

10.1128/genomea.00342-16 article EN Genome Announcements 2016-06-30

The study was conducted to describe the cultural characteristics such as colour and texture of leaf blast pathogen Pyricularia oryzae (Cav.) on different solid media viz., potato dextrose agar, carrot Kirchoff’s, medium, Richard’s Sabourad’s Takahashii’s rice extract agar oat meal liquid broth, Kirchoff’s broth broth. Among all highest mean mycelial growth fungus recorded (77.6mm) followed by (75.9mm) least P. (44.7mm) (52.5mm). maximum dry weight in (211.56mg) (206.3mg) (178.0mg) (179.7mg)....

10.20546/ijcmas.2017.606.133 article EN International Journal of Current Microbiology and Applied Sciences 2017-06-10

Abstract Fruiting bodies of mushroom-forming fungi (Agaricomycetes) are among the most complex structures produced by fungi. Unlike vegetative hyphae, fruiting grow determinately and follow a genetically encoded developmental program that orchestrates tissue differentiation, growth sexual sporulation. In spite more than century research, our understanding molecular details body morphogenesis is limited general synthesis on genetics this process lacking. paper, we aim to comprehensively...

10.1101/2021.12.09.471732 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-12-10

Abstract Fungi are among the most ecologically important heterotrophs that have radiated into niches on Earth and fulfil key ecological services. However, despite intense interest in their origins, major genomic trends characterising evolutionary route from a unicellular opisthokont ancestor to derived multicellular fungi remain poorly known. Here, we reconstructed gene family evolution across 123 genomes of relatives show dominant trend early fungal has been gradual shedding protist genes...

10.1101/2022.11.15.516418 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-11-15

Abstract Members of the fungal genus Armillaria are necrotrophic pathogens with efficient plant biomass-degrading strategies. The includes some largest terrestrial organisms on Earth, spreading underground and causing tremendous losses in diverse ecosystems. Despite their global importance, mechanism by which evolved pathogenicity a clade dominantly non-pathogenic wood-degraders (Agaricales) remains elusive. Here, using new genomic data, we show that species, addition to widespread gene...

10.1101/2022.11.10.515791 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-11-13
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