- Plant Virus Research Studies
- Fungal Biology and Applications
- Plant tissue culture and regeneration
- Plant and Fungal Interactions Research
- Plant Pathogens and Fungal Diseases
- Transgenic Plants and Applications
- Plant Disease Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Mycorrhizal Fungi and Plant Interactions
- Insect-Plant Interactions and Control
- Animal Virus Infections Studies
- Plant Reproductive Biology
- Fungal and yeast genetics research
- Plant Pathogenic Bacteria Studies
- CRISPR and Genetic Engineering
- Toxin Mechanisms and Immunotoxins
- Veterinary medicine and infectious diseases
- Microbial Natural Products and Biosynthesis
- Insect and Pesticide Research
- Nematode management and characterization studies
- Plant biochemistry and biosynthesis
- Insect Resistance and Genetics
- Plant Pathogens and Resistance
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
University of Bristol
2016-2025
National Research Institute for Earth Science and Disaster Resilience
2023
Ghent University
2023
UCLouvain
2023
Wageningen University & Research
2023
Royal Observatory of Belgium
2023
Cabot (United States)
2011-2020
Queen Mary University of London
2018
Planta
1999-2008
University of Leeds
2008
Agaricus bisporus is the model fungus for adaptation, persistence, and growth in humic-rich leaf-litter environment. Aside from its ecological role, A. has been an important component of human diet over 200 y worldwide cultivation "button mushroom" forms a multibillion dollar industry. We present two genomes, their gene repertoires transcript profiles on compost during mushroom formation. The genomes encode full repertoire polysaccharide-degrading enzymes similar to that wood-decayers....
Figure 2 in this paper depicts the infection cycle of rice blast fungus Magnaporthe oryzae. The scanning electron microscope image bottom right figure was first published Mendgen K, Lesemann D-E (eds). 1991. Electron Microscopy Plant Pathogens, Springer-Verlag, Berlin. This should have been acknowledged accompanying legend. authors apologise for oversight. An updated version can be viewed online at http://onlinelibrary.wiley.com/doi/10.1111/j.1364-3703.2011.00783.x/full
Fungi are often inconspicuous in nature and this means it is all too easy to overlook their importance.Often referred as the "Forgotten Kingdom", fungi key components of life on planet.The phylum Basidiomycota, considered contain most complex evolutionarily advanced members Kingdom, includes some iconic fungal species such gilled mushrooms, puffballs bracket fungi.Basidiomycetes inhabit a wide range ecological niches, carrying out vital ecosystem roles, particularly carbon cycling symbiotic...
Abstract Semi-synthetic derivatives of the tricyclic diterpene antibiotic pleuromutilin from basidiomycete Clitopilus passeckerianus are important in combatting bacterial infections human and veterinary medicine. These compounds belong to only new class antibiotics for applications, with novel mode action lack cross-resistance, representing a great potential. Basidiomycete fungi, being dikaryotic, not generally amenable strain improvement. We report identification seven-gene gene cluster...
Abstract The rise in antibiotic resistance is a major threat for human health. Basidiomycete fungi represent an untapped source of underexploited antimicrobials, with pleuromutilin—a diterpene produced by Clitopilus passeckerianus —being the only from these leading to commercial derivatives. Here we report genetic characterisation steps involved pleuromutilin biosynthesis, through rational heterologous expression Aspergillus oryzae coupled isolation and detailed structural elucidation...
A partial sequence of 1114 nucleotides a virus from cassava brown streak diseased (CBSD) material was obtained. Alignment the predicted amino acid with those other members Potyviridae showed closest identity coat protein Sweet potato mild mottle (genus Ipomovirus ). The has one open reading frame 3′ untranslated region 144 and poly(A) tail. expressed shown to cross‐react an antiserum raised previously isolated CBSD material. Evidence presented suggests that is caused by Cassava , tentative...
The viral component of Turnip mosaic virus (TuMV) determining virulence to the Brassica napus TuRB01 dominant resistance allele has been identified. Sequence comparisons an infectious cDNA clone UK 1 isolate TuMV (avirulent on TuRB01) and a spontaneous mutant capable infecting plants possessing suggested that single nucleotide change in cylindrical inclusion (CI) protein coding region (gene) was responsible for altered phenotype. A second mutation involved different CI gene. construction...
An RT‐PCR based detection method for Cassava brown streak virus (CBSV)‐infected cassava has been developed. The described includes RNA extraction methods leaves, a distinct primer set the and conditions. primers were designed to coat protein gene generate virus‐specific product of 231 bp from infected cassava. test can detect in new growth sticks before any disease symptoms are visible. This was used successfully with both Tanzania Mozambique. Three isolates found exhibit different on...
Pleuromutilin is a broad-spectrum antibiotic that has been used in veterinary medicine for over 20 years, but now gaining interest as human therapeutic. The compound fungal secondary metabolite, there some degree of confusion within the literature concerning which species may produce pleuromutilin, with several differently named fungi reported to make compound. Here, we describe taxonomic survey publicly available cultures known and other similar species. pleuromutilin production these...
Differences in the early responses of two potato cultivars, Igor and Nadine, to isolates Potato virus Y (PVY), aggressive PVY NTN mild N , were monitored. Microarray quantitative real‐time PCR analyses carried out identify differentially expressed genes after inoculation with each isolate. Additionally, symptom severity development was observed amount isolate accumulated systemically infected leaves evaluated, where a significantly higher detected. analysis revealed 572, 1288 1706 at 0·5, 12...
Stomata are important regulators of carbon dioxide uptake and transpirational water loss. They also represent points vulnerability as bacterial fungal pathogens utilise this natural opening an entry portal, thus have increasingly complex relationship. Unlike the situation with pathogens, we know very little about role stomata in viral infection. Here report findings showing that infection influences stomatal development two susceptible host systems (Nicotiana tabacum TMV (Tobacco mosaic...
Vector-borne plant virus research straddles virology, entomology, agricultural practices and international trade policies practices. Reducing crop losses from viruses to better secure global food supplies necessitates interdisciplinary collaboration improvement capacity. A UK Government-funded community network, the Community Network for Vector-Borne Plant Viruses (CONNECTED) aimed increase capacity in vector-borne through a multi-year programme of activities. Using network analysis, we show...