A5072045961- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Inflammatory Bowel Disease
- Anorectal Disease Treatments and Outcomes
- Diverticular Disease and Complications
- Nutrition and Health in Aging
- Microscopic Colitis
- Cancer survivorship and care
- Autoimmune and Inflammatory Disorders
- Gut microbiota and health
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Dietary Effects on Health
- Gastrointestinal disorders and treatments
- Enhanced Recovery After Surgery
- Peripheral Artery Disease Management
- Pelvic floor disorders treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
University of Washington
2015-2025
University of Washington Medical Center
2015-2023
Fred Hutch Cancer Center
2020-2023
University of Florida
2022
Seattle University
2015-2020
University of Chicago
2012-2015
University of Chicago Medical Center
2011-2014
Deutsches Herzzentrum München
2009
München Klinik
2009
The impact of infliximab on the postoperative course patients with IBD is under debate.The aim this study was to evaluate influence perioperative outcomes in undergoing elective laparoscopic resection for IBD.This a retrospective analysis prospectively collected, institutional review board-approved database. SETTING, PATIENTS, INTERVENTIONS: Patients preoperative (infliximab group) were compared who did not receive (noninfliximab group).The short-term and long-term morbidity mortality rates...
Abstract Background Physical activity and BMI have been individually associated with cancer survivorship but not yet studied in combinations colorectal patients. Here, we investigate individual combined associations of physical groups survival outcomes. Methods Self-reported levels (MET hrs/wk) were assessed using an adapted version the International Activity Questionnaire (IPAQ) at baseline 931 patients stage I-III classified into ‘highly active’ and’not-highly active’(≥ / < 18 MET...
Early-onset colorectal cancer has been on the rise in Western populations. Here, we compare patient characteristics between those with early- (<50 years) vs. late-onset (≥50 disease a large multinational cohort of patients (n = 2193). We calculated descriptive statistics and assessed associations clinicodemographic factors age onset using mutually-adjusted logistic regression models. Patients were average 60 years old, BMI 29 kg/m2, 52% colon cancers, 21% early-onset, presented stage II or...
BACKGROUND: Postoperative recurrence remains a significant problem in Crohn’s disease, and the mesentery is implicated pathophysiology. The Kono-S anastomosis was designed to exclude from wide anastomotic lumen, limit luminal distortion fecal stasis, preserve innervation vascularization. OBJECTIVE: To review postoperative complications long-term outcomes of large series consecutive unselected patients with disease. DESIGN: Retrospective study prospectively collected patients. SETTINGS: Four...
Abstract Background: Individuals with adenomatous colorectal polyps undergo repeated colonoscopy surveillance to identify and remove metachronous adenomas. However, many patients adenomas do not develop recurrent Better methods evaluate who benefits from increased are needed. We evaluated the use of altered EVL methylation as a potential biomarker for risk Methods: Patients ≥1 had (mEVL) measured an ultra-accurate methylation-specific droplet digital PCR assay on normal colon mucosa. The...
Abstract Background: Physical activity and obesity are well-established factors of colorectal cancer risk prognosis. Here, we investigate associations individual combined physical body mass index (BMI) groups with proinflammatory biomarkers in patients. Methods: Self-reported levels were classified as “active” (≥8.75 MET-hours/week) versus “inactive” (&lt;8.75 n = 579 stage I–IV patients enrolled the ColoCare Study. BMI [normal weight (≥18.5–&lt;25 kg/m2), overweight (≥25–&lt;30...
<p>Supplemental Table 7: Summary statistics for methylated EVL measurements in Comparison Set 3</p>
<p>Supplemental Figure 3: EVL methylation levels of normal colon for patients with no history adenoma or cancer after initial colonoscopy (left group) and an colorectal detected (middle group). Patients follow-up colonoscopies (right were not included in the analyses Comparison Set 2. %mEVL=percentage DNA that is methylated at locus assayed.</p>
<p>Supplemental Figure 2: Methylation levels of normal colon mucosa in patients with no history adenoma or cancer ever (group on left) and for a adenoma(s) colorectal at initial follow-up colonoscopy right) Comparison Set 1. %mEVL=percentage DNA that is methylated the EVL locus assayed.</p>
<p>Supplemental Table 5: Summary statistics for methylated EVL measurements in Comparison Set 1</p>
<p>Supplemental Table 5: Summary statistics for methylated EVL measurements in Comparison Set 1</p>