A5084977220- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- COVID-19 Clinical Research Studies
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- Ultrasound Imaging and Elastography
- Blood Pressure and Hypertension Studies
- Electrical and Bioimpedance Tomography
- Cardiovascular Function and Risk Factors
- Ultrasound and Hyperthermia Applications
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Valve Diseases and Treatments
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Scientific Measurement and Uncertainty Evaluation
- Long-Term Effects of COVID-19
- Electrostatic Discharge in Electronics
- Gastroesophageal reflux and treatments
- Artificial Intelligence in Healthcare and Education
Cedars-Sinai Smidt Heart Institute
2020-2025
Cedars-Sinai Medical Center
2020-2025
Sinai Health System
2020-2024
University of Miami
2013-2019
Jackson Memorial Hospital
2016
Duke University
2007
Background Despite a lack of clinical evidence, hydroxychloroquine and azithromycin are being administered widely to patients with verified or suspected coronavirus disease 2019 (COVID-19). Both drugs may increase risk lethal arrhythmias associated QT interval prolongation. Methods Results We analyzed case series COVID-19-positive/suspected admitted between February 1, 2020, April 4, who were treated azithromycin, hydroxychloroquine, combination both drugs. evaluated baseline postmedication...
Active esophageal cooling reduces the incidence of endoscopically identified severe lesions during radiofrequency (RF) catheter ablation left atrium for treatment atrial fibrillation. A formal analysis atrioesophageal fistula (AEF) rate with active has not previously been performed.
Arrhythmias have been reported frequently in COVID-19 patients, but the incidence and nature not well characterized. Patients admitted with monitored by telemetry were prospectively enrolled study. Baseline characteristics, hospital course, treatment complications collected from patients' medical records. Telemetry was to detect of cardiac arrhythmias. The types arrhythmias analyzed compared between survivors non-survivors. Among 143 patients monitoring, overall in-hospital mortality 25.2%...
ABSTRACT Background Despite a paucity of clinical evidence, hydroxychloroquine and azithromycin are being administered widely to patients with verified or suspected COVID-19. Both drugs may increase risk lethal arrhythmias associated QT interval prolongation. Methods We performed case series COVID-19 positive/suspected admitted between 2/1/2020 4/4/2020 who were treated azithromycin, combination. evaluated baseline post-medication (QTc, Bazett’s) using 12-lead ECGs. Critical QTc prolongation...
Multipolar mapping, a novel method of electrogram acquisition and annotation distinct from unipolar bipolar acquisitions, provides orientation-independent near-field signal with enhanced spatial precision. mapping use in humans has not been described. This study aimed to present findings on the multipolar variety different arrhythmia types mechanisms. We performed consecutive ablation procedures using high-density multipolar-capable catheter (OPTRELL, Biosense Webster, Irvine, CA). Parallel...
ABSTRACT Background Various methods have been used to identify substrate of persistent atrial fibrillation (PeAF) including complex fractionated electrograms (CFAEs), electrogram dispersion, and low‐voltage areas (LVAs). This study aims investigate their relationship changes following ablation. Methods Results Consecutive patients with PeAF undergoing catheter ablation were prospectively recruited. High‐density left mapping was employed. Repeat performed after pulmonary vein posterior wall...
Abstract Transendocardial stem cell injection in patients with ischemic cardiomyopathy (ICM) improves left ventricular function and structure but has ill-defined effects on arrhythmias. We hypothesized that mesenchymal (MSC) implantation is not proarrhythmic. Post hoc analyses were performed ambulatory ECGs collected from the POSEIDON TAC-HFT trials. Eighty-eight subjects (mean age 61 ± 10 years) ICM EF 32.2% 9.8%) received treatment MSC (n = 48), Placebo 21), or bone marrow mononuclear...
1 Background In the United States, life expectancy is rising, particularly among older population (≥ 65 years), with projected estimates approaching 20% by year 2050. (1) Despite im- proved survival estimates, cardiovascular diseases remain leading cause of morbidity and mortality resulting in substantial increase health care cost. (2) For younger adults, evidence for secondary prevention well established corroborated robust data. However, application risk reduction strategies populations...
Abstract Introduction Proactive esophageal cooling has been FDA cleared to reduce the likelihood of ablation‐related injury resulting from radiofrequency (RF) cardiac ablation procedures. Data suggest that procedure times for RF pulmonary vein isolation (PVI) also decrease when proactive is employed instead luminal temperature (LET) monitoring. Reduced may allow increased electrophysiology (EP) lab throughput. We aimed quantify change in EP throughput PVI cases after introduction cooling....
Based upon evidence suggesting that concentrations of anti-heat shock protein-60 (anti-HSP60) and interleukin-2 (IL-2) are associated with atherogenesis, we tested the hypothesis anti-HSP60 IL-2 coronary artery calcium (CAC) score, a marker subclinical atherosclerosis.We evaluated 998 asymptomatic adults, age 45-84 years, without known disease from Multi-Ethnic Study Atherosclerosis (MESA), who had measured at baseline. Tertiles serum were evaluated. The associations CAC assessed using...
ABSTRACT Background Active esophageal cooling reduces the incidence of endoscopically identified severe lesions during radiofrequency (RF) catheter ablation left atrium for treatment atrial fibrillation. No atrioesophageal fistula (AEF) has been reported to date with active cooling, and only one pericardio-esophageal reported; however, a formal analysis AEF rate not previously performed. Methods Atrial fibrillation procedure volumes before after adoption using dedicated device (ensoETM,...
Introduction : Proactive esophageal cooling has been FDA cleared to reduce the likelihood of ablation-related injury resulting from radiofrequency (RF) cardiac ablation procedures. Data suggest that procedure times for RF pulmonary vein isolation (PVI) also decrease when proactive is employed instead luminal temperature (LET) monitoring. Reduced may allow increased electrophysiology (EP) lab throughput. We aimed quantify change in EP throughput PVI cases after introduction cooling. Methods...