- Adipose Tissue and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Plant-based Medicinal Research
- Pharmacology and Obesity Treatment
- Muscle Physiology and Disorders
- Inflammatory mediators and NSAID effects
- Cardiovascular and exercise physiology
- Neurological Disease Mechanisms and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Autophagy in Disease and Therapy
- Diabetes Treatment and Management
- Inflammasome and immune disorders
- Medicinal plant effects and applications
- Histone Deacetylase Inhibitors Research
Army Medical University
2019-2023
Abstract Background Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays crucial role in type transition. In this study, we assessed the effects natural flavonoid myricetin on exercise muscle fiber constitution, further investigated underlying mechanism vivo vitro. Methods A total 66 six-week-old male Sprague Dawley rats were divided into non-exercise or groups...
The purpose of this study was to examine whether endogenous GLP-1 (glucagon-like peptide-1) could respond exercise training in mice, as well dihydromyricetin (DHM) supplementation enhance levels response training. After 2 weeks intervention, we found that were significantly elevated. A reshaped gut microbiota identified following exercise, evidenced by the increased abundance Bifidobacterium, Lactococcus, and Alistipes genus, which are involved production short-chain fatty acids (SCFAs)....
Cardiovascular adverse effects caused by high-intensity exercise (HIE) have become a public health problem of widespread concern. The therapeutic effect and metabolic regulation mechanism myricetin, phytochemical with potential effects, rarely been studied. In this study, we established mice models different doses myricetin intervention 1 week HIE after intervention. Cardiac function tests, serology, pathological examinations were used to evaluate the protective on myocardium. possible...
The study investigated the effect of pterostilbene (PTE) on intestinal glucose absorption and its underlying mechanisms in high-intensity swimming exercise (HISE)-treated mice. Male C57BL/6 mice were treated with PTE for 4 weeks performed training last week. Intestinal epithelial cells (IECs) pretreated 0.5 1.0 μM 24 h before being incubated hypoxia/reoxygenation condition. was detected by using an oral tolerance test d-xylose assay, levels factors related to mitochondrial function...
An amendment to this paper has been published and can be accessed via the original article.