A5044904303- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Genetics, Aging, and Longevity in Model Organisms
- Cardiovascular Disease and Adiposity
- Patient Dignity and Privacy
- Family Support in Illness
- Colorectal Cancer Screening and Detection
- Renal Transplantation Outcomes and Treatments
- Digital Radiography and Breast Imaging
- Global Cancer Incidence and Screening
- Bipolar Disorder and Treatment
- Nutrition, Genetics, and Disease
- Adipose Tissue and Metabolism
- Cardiovascular Function and Risk Factors
- Pressure Ulcer Prevention and Management
- Medication Adherence and Compliance
Massachusetts General Hospital
2022-2023
Johns Hopkins University
2023
Johns Hopkins Medicine
2023
Harvard University
2019
Harvard Stem Cell Institute
2019
Harvard University Press
2018
Social support is essential to the recovery of patients who have undergone hematopoietic stem cell transplantation (HSCT). We undertook a qualitative study explore specific sources and benefits social as experienced by HSCT recipients, well their unmet needs. conducted semistructured interviews with 25 recipients recruited from Dana Farber Cancer Institute's database. The explored that receive, type assistance networks provide patients, needs support. Interviews were audio-recorded,...
Background: Many patients with advanced cancer have misperceptions of their prognosis, which may impact end-of-life decision-making. Data regarding associations between prognostic perceptions over time and care outcomes are lacking. Aim: To describe patients’ prognosis examine these outcomes. Design: Secondary analysis longitudinal data from a randomized controlled trial palliative intervention for newly diagnosed incurable cancer. Setting/Participants: Conducted at an outpatient center in...
Calorie restriction (CR) improved health span in 2 longitudinal studies nonhuman primates (NHPs), yet only the University of Wisconsin (UW) study demonstrated an increase survival CR monkeys relative to controls; National Institute on Aging (NIA) did not. Here, analysis left ventricle samples showed that not reduce cardiac fibrosis controls. However, there was a 5.9-fold total UW hearts, compared with NIA hearts. Diet composition prominent difference between studies; therefore, we used NHP...
Patients with high-risk acute myeloid leukemia (AML) often experience intensive medical care at the end of life (EOL), including high rates hospitalizations and unit (ICU) admissions. Despite this, studies examining code status transitions are lacking. We conducted a mixed-methods study 200 patients AML enrolled in supportive Massachusetts General Hospital between 2014 2021. defined as relapsed/refractory or diagnosis age ≥60. used consensus-driven record review to characterize transitions....
Caloric restriction (CR) has been shown to decrease aging and increase the lifespan of several model organisms. However, in two on-going independent, long-term CR studies non-human primates (NHP) at National Institute Aging (NIA) University Wisconsin, Madison (UW) outcome more complex. While monkeys UW study have experienced a significant relative their controls, this was not case for NIA study. There, did compared already long-lived controls. Yet, both associated with occurrence age-related...
Calorie restriction (CR) improved healthspan in two longitudinal studies nonhuman primates (NHPs) aimed at investigating the effect of this nutritional intervention on markers health and survival. However, only University Wisconsin (UW) study demonstrated an increase survival CR monkeys relative to controls; National Institute Aging (NIA) did not. Using samples from these studies, we investigated chronic myocardial aging. Age‐associated cardiac changes NHPs are similar those humans, as such,...