- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Muscle metabolism and nutrition
- Nutritional Studies and Diet
- Dietary Effects on Health
- Eating Disorders and Behaviors
- Cardiovascular and exercise physiology
- Physical Activity and Health
- Exercise and Physiological Responses
- Hormonal and reproductive studies
University of Toronto
2013-2019
Abstract Background: Obesity is associated with increased consumption and preference for dietary fat. Experimental models of fat-induced obesity use either lard or vegetable shortening. Yet, there are no direct comparisons these commonly used fat sources, the influence their fatty acid composition, on development diet-induced obesity. Objective: To compare effects hydrogenated vegetable-shortening diets, which differ in weight gain insulin resistance rats. Methods design: Male Wistar rats...
High-intensity exercise (HIEX) suppresses appetite in adults and is thought to be mediated by appetite-regulating hormones. However, the effects of HIEX-induced inflammatory stress biomarkers on control body weight have not been reported children or adults. The objective this study was describe acute HIEX at 70% peak oxygen consumption (VO2peak) postexercise selective inflammation, stress, regulatory hormones normal-weight (NW) overweight/obese boys. NW (n = 11) boys aged 10–18 y were...
Abstract Background: The effect of carbohydrate (CHO) foods on blood glucose (BG) is ranked by their glycemic index (GI). Boiled and mashed potatoes (BMPs) are as high GI foods, whereas pasta rice have moderate rankings. objective this study was to compare ad libitum consumption common CHO dishes consumed with meat meal-time food intake post-meal satiety, BG, insulin gut hormones in 11- 13-year-old normal weight children. Methods: Two randomized crossover studies were conducted. At weekly...
The acute relationship between substrate oxidation as measured by respiratory exchange ratio (RER) and food intake (FI) has not been defined. purpose of the study was to determine relationships RER, modified exercise a glucose load, FI net energy balance (NEB) in physically active normal-weight boys men. In crossover design, 15 (aged 9-12 years) men 20-30 were randomly assigned 4 conditions: (i) water rest, (ii) glucose-drink (iii) exercise, (iv) exercise. Indirect calorimetry used...
Our previous study showed that interleukin-6 (IL-6) is associated with suppression of appetite after high-intensity exercise (HIEX), but an independent role in food intake (FI) was not defined. We hypothesized IL-6 suppresses and FI, independently hormones, HIEX normal-weight (NW) boys. investigated the effect HIEX, without inflammation inhibitor ibuprofen (IBU), on IL-6, other biomarkers appetite, ratings NW Fifteen boys (aged 13–18 years) were randomly assigned a crossover design to 4...
Background Obesity is associated with increased consumption and preference for dietary fat. Experimental models of fat‐induced obesity use either lard or vegetable shortening. Yet, there are no direct comparisons these commonly used fat sources, the influence their fatty acid composition on development diet‐induced obesity. Objective To compare effects hydrogenated shortening diets, which differ in composition, weight gain insulin resistance rats. Methods Design Male Wistar rats were fed ad...
Abstract Objective Chronic testosterone blood concentrations associate with food intake (FI), but acute effects of on appetite and effect protein glucose consumption response have had little examination. Methods In a randomized, crossover study, twenty‐three adolescent (12‐18 years old) males were given beverages containing either: (a) whey (1 g/kg body weight), (b) weight) or (c) calorie‐free control (C). Plasma testosterone, luteinizing hormone (LH), GLP‐1 (active), ghrelin (acylated),...
Background High intensity exercise (HIE) suppresses appetite in adults and is thought to be mediated by regulating hormones. It also affects a variety of other controlling mechanism, such as inflammation stress. Rationale Although the role hormones HIE suppression has received much attention, their remains unclear. Hypothesis induces reduction due an increase stress related responses. Objective To investigate compare underlying mechanisms contributing with obese lean children. Methods...
The effect of metabolic flexibility and the associated changes in substrate oxidation (measured via respiratory exchange ratio; RER) on short‐term food intake (FI) is not well understood. objective this study was to examine relationship between RER after a glucose drink (GL) exercise (EX) FI energy balance (EB) normal body weight (BW) boys (N=15;age:9–12y) men (N=15;age:20–30y). Subjects participated 4 conditions random order. They received either water or GL followed by moderate EX rest....