Takuya Saito

ORCID: 0000-0003-4963-9369
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Venous Thromboembolism Diagnosis and Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Peripheral Neuropathies and Disorders
  • Multiple Sclerosis Research Studies
  • Neurological Disease Mechanisms and Treatments
  • Aortic Disease and Treatment Approaches
  • Stroke Rehabilitation and Recovery
  • Neurological and metabolic disorders
  • Intracranial Aneurysms: Treatment and Complications
  • Restraint-Related Deaths
  • Spinal Cord Injury Research
  • Oropharyngeal Anatomy and Pathologies
  • Myasthenia Gravis and Thymoma
  • Alcoholism and Thiamine Deficiency
  • Vascular Malformations Diagnosis and Treatment
  • Aortic aneurysm repair treatments
  • Cardiovascular and Diving-Related Complications
  • Treatment of Major Depression
  • Histiocytic Disorders and Treatments
  • Pathogenesis and Treatment of Hiccups
  • Dysphagia Assessment and Management
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Kohnan Hospital
2017-2024

Nihon University
2024

Sendai City Hospital
2024

Seirei Hamamatsu General Hospital
2023-2024

Hyogo University
2023

Hokkaido University Hospital
2023

International Rescue System
2022

Kyoto University
2000

Endovascular therapy for acute ischemic stroke is generally avoided when the infarction large, but effect of endovascular with medical care as compared alone large strokes has not been well studied.

10.1056/nejmoa2118191 article EN New England Journal of Medicine 2022-02-09

Endovascular therapy (EVT) has been found to reduce functional disability in patients with acute stroke due large-vessel occlusion. However, the extent of ischemic region, measured using Alberta Stroke Program Early Computed Tomography Scores, may limit efficacy EVT.To compare and safety EVT according ASPECTS 3 or less vs 4 5.The Recovery by Salvage for Cerebral Ultra-acute Embolism-Japan Large Ischemic Core Trial (RESCUE-Japan LIMIT) was an open-label randomized clinical trial conducted...

10.1001/jamaneurol.2022.3285 article EN JAMA Neurology 2022-10-10

Background and Purpose— The treatment prognosis of acute large vessel occlusion with mild symptoms have not been sufficiently studied. present study aimed to investigate the clinical or radiological predictors outcome in patients stroke due occlusion. Methods— Of 2420 RESCUE-Japan Registry 2 (Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism-Japan 2), a multicenter prospective registry Japan, modified Rankin Scale scores 0 before onset initial National Institutes Health...

10.1161/strokeaha.119.028562 article EN Stroke 2020-04-16

We present a case of rocuronium-induced hypertensive crises that occurred twice in patient with paraganglioma. An 86-year-old woman was first scheduled for laminectomy lumbar spinal stenosis. Five minutes after intravenous induction anesthesia using fentanyl, propofol, rocuronium, and remifentanil, the patient's blood pressure (BP) heart rate (HR) suddenly increased no stimuli. Surgery postponed because suspected having pheochromocytoma. After that, paraganglioma diagnosed, surgery removal...

10.7759/cureus.59868 article EN Cureus 2024-05-08

Abstract Backgrounds The main culprit lesion causing hiccup in patients with ischemic stroke is thought to involve the medulla oblongata, but some cases of hiccups caused by damage supratentorial cortex have been reported. present study aimed address clinical and radiological characteristics acute accompanied lesions. Method We retrospectively studied 5,309 consecutive or transient attack who were admitted our institute within 7 days after onset between April 2006 September 2017. searched...

10.1002/brb3.1439 article EN cc-by Brain and Behavior 2019-10-15

<b><i>Introduction:</i></b> Both collateral flow via the internal carotid artery (ICA) terminus (ICT) and initial mild symptoms might be associated with favorable outcomes in patients acute ICA occlusion (ICAO). This study aimed to address association between early clinical patency of ICT middle cerebral (MCA) ICAO symptoms. <b><i>Methods:</i></b> Of 1,214 consecutive ischemic stroke or transient attack due large vessel occlusion, ipsilateral...

10.1159/000527635 article EN cc-by-nc Cerebrovascular Diseases Extra 2022-10-24

Planning for the acute phase of ischemic stroke in postoperative patients with aortic dissection is difficult from perspective concerns about worsening disease related to due intravenous thrombolytic agents and securing access routes when mechanical thrombectomy planned. Herein, we report that a 52-year-old man underwent thoracic endovascular repair type B dissection. One year after procedure, patient developed caused by stent graft thrombosis, computed tomography angiography showed...

10.7759/cureus.64465 article EN Cureus 2024-07-13

Sturge-Weber syndrome (SWS) is a rare congenital disorder associated with systemic vascular malformations characterized by port-wine stains, epilepsy, and glaucoma. Patients SWS can develop stroke-like symptoms such as hemiparesis. We report case of 63-year old woman who developed left-sided hemiparesis was finally diagnosed myelin-oligodendrocyte glycoprotein (MOG) antibody-positive encephalitis. Brain magnetic resonance imaging (MRI) revealed right-dominant bilateral leptomeningeal...

10.1016/j.radcr.2024.01.006 article EN cc-by Radiology Case Reports 2024-01-13

A 69-year-old man, with a history of left superficial temporal artery-middle cerebral artery bypass due to infarction by internal carotid occlusion, was hospitalized acute right hemispatial neglect and hemiparesis. Diffusion-weighted imaging showed high-intensity lesion in the insular cortex. Although there seemed be no arterial occlusion magnetic resonance angiography (MRA), non-contrast computed tomography (CT) on admission calcification Sylvian fissure. As hyperacute ischemic stroke...

10.7759/cureus.52593 article EN Cureus 2024-01-19

Both neuromyelitis optica spectrum disorder (NMOSD) and Wernicke's encephalopathy (WE) involve brain lesions. However, their treatments are quite different. In this report, we describe the case of a 29-year-old woman with NMOSD, who presented clinical imaging findings similar to those WE. She was admitted our hospital headache, vomiting, loss appetite for two weeks diplopia nine days. Magnetic resonance revealed lesions in area postrema, periaqueductal gray matter, thalamus, right frontal...

10.7759/cureus.63920 article EN Cureus 2024-07-05

Myasthenia gravis (MG) is characterized by weakness and rapid fatigue of voluntary muscles. Here, we present two cases early-onset MG, complicated with M-proteinemia demyelinating neuropathy. Case one was diagnosed MG at age 29, received tacrolimus post-thymectomy, developed neuropathies 66 before being B-cell lymphoma. 21, immunosuppressive drugs myelin-associated glycoprotein antibody-associated neuropathy 66. Demyelinating M-proteinuria should be considered when motor symptoms worsen in...

10.7759/cureus.74886 article EN Cureus 2024-12-01

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease that causes recurrent neuritis and myelitis. Ravulizumab, a complement protein C5 inhibitor, was developed to treat NMOSD. However, its efficacy in improving symptoms remains unclear. This case report describes the of 30-year-old woman with NMOSD who thoracic Initial treatment high-dose methylprednisolone hemodialysis alleviated paraplegia, although urinary retention persisted. Two months after initiating ravulizumab...

10.7759/cureus.75827 article EN Cureus 2024-12-16

We report a case of persistent consciousness disturbance due to non-convulsive status epilepticus (NCSE) following successful mechanical thrombectomy (MT). A 98-year-old female with atrial fibrillation presented impaired and right hemiparesis 6 hrs after her last known well state. Magnetic resonance angiography revealed occlusion the left internal carotid artery, necessitating MT achieve complete recanalisation. Following admission, showed no signs improvement, electroencephalography (EEG)...

10.2176/jns-nmc.2024-0181 article EN NMC Case Report Journal 2024-12-24

Introduction Whole-body computed tomography angiography (CTA) may be useful during cerebral and endovascular treatment (EVT), identification of thrombi malignant trunk tumors helpful in stroke typing acute care. Therefore, we aimed to assess the types prevalence incidental findings on whole-body CTA this patient population. Methods This single-center, retrospective, observational study included consecutive patients with suspected who underwent addition brain between April 2020 August 2023....

10.7759/cureus.76639 article EN Cureus 2024-12-30

Objectives This study clarified the usefulness of carotid duplex ultrasound (CDU) in evaluating large vessel occlusion (LVO) patients with acute stroke planned to be treated mechanical thrombectomy (MT).

10.2169/internalmedicine.0029-22 article EN Internal Medicine 2023-02-28
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