Antonino Mazzone
A5054771692- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Neuropeptides and Animal Physiology
- Atherosclerosis and Cardiovascular Diseases
- Long-Term Effects of COVID-19
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Sepsis Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Healthcare cost, quality, practices
- Systemic Sclerosis and Related Diseases
- Acute Myocardial Infarction Research
- Chronic Disease Management Strategies
- Hematological disorders and diagnostics
- Pharmacological Receptor Mechanisms and Effects
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
- Innovations in Medical Education
- Healthcare Quality and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood disorders and treatments
- Chronic Lymphocytic Leukemia Research
- Clinical Reasoning and Diagnostic Skills
- Cell Adhesion Molecules Research
Azienda Ospedaliera Ospedale Civile di Legnano
2016-2025
Aziende Socio Sanitarie Territoriale Ovest Milanese
2016-2025
Azienda Socio Sanitaria Territoriale Lariana
2020-2025
ASST Melegnano e della Martesana
2017-2024
Ospedale Maggiore
2013-2021
Weatherford College
2021
Paradise Valley Hospital
2020-2021
Committee on Publication Ethics
2021
German BioImaging – Gesellschaft für Mikroskopie und Bildanalyse
2020
Technical University of Munich
2019
BACKGROUND A rapid increase in leukocyte adhesion to endothelial cells is one of the first events acute inflammatory response and pathogenesis vascular diseases. subgroup cell surface glycoproteins (the CD11/CD18 complex) play a major role process; particular, CD11b/CD18 receptor can be upregulated severalfold chemotactic factors. The purpose this study was assess whether upmodulation granulocyte monocyte receptors takes place during passage blood through coronary tree patients with clinical...
To assess fetal and maternal outcomes in women with systemic sclerosis (SSc).Prospectively collected data on 99 SSc from 25 Italian centers were analyzed retrospectively. Women observed during 109 pregnancies (from 2000 to 2011), compared those the general obstetric population (total of 3,939 deliveries). The age at conception was a mean ± SD 31.8 5.3 years, median disease duration 60 months (range 2-193 months).SSc patients, population, had significantly increased frequency preterm...
In patients with severe SARS-CoV-2 infection, the development of cytokine storm induces extensive lung damage, and monocytes play a role in this pathological process. Non-classical (NC) intermediate (INT) are known to be involved during viral bacterial infections. study, 30 different manifestations acute infection were investigated flow cytometric study NC, INT, classical (CL) monocytes. Significantly reduced NC INT downregulated HLA-DR found symptoms. Conversely moderate symptoms CD11b...
To determine whether percutaneous transluminal coronary angioplasty (PTCA) would lead to neutrophil activation with subsequent discharge of proteolytic enzymes, like elastase, and oxygen free radicals, superoxide anion, blood samples were taken from the sinus aorta in 14 patients stable angina one-vessel disease who underwent PTCA. Neutrophils separated by means Ficoll-Hypaque system stimulated detect release elastase generation anion. Plasma levels also measured an immunoenzymatic method....
3][4][5][6] This case report illustrates the potential of COVID-19 infections to trigger severe drug-related skin reactions such as vasculitis.More evidence is needed understand association and cutaneous manifestations.
Abstract COVID-19 is causing a high influx of patients suffering from serious respiratory complications leading the necessity to find effective therapies. These seem present with cytokine perturbation and levels IL6. Tocilizumab sarilumab could be in this condition. We retrospectively collected data about 112 consecutive hospitalized single center. Fifty (IL6 group) treated tocilizumab (8 mg/kg intravenously [IV], 2 infusions 12 hours apart) or 400 mg IV once 62 standard care but not...
Progression of atherosclerosis is currently believed to involve interactions between leukocytes and vascular endothelium. Epidemiological risk factors for such as hypertension smoking are known cause endothelial dysfunction, which an early event in the atherosclerotic process; they also may be considered light their effects on adhesion molecule expression release. Little about additive effect these two nitric oxide Soluble molecules were quantified hypertensive patients comparison those from...
Abstract Although myocarditis can be a severe cardiac complication of COVID-19 patients, few data are available in the literature about incidence and clinical significance patients affected by SARS-CoV-2. This study aims to describe prevalence features suspected 3 cohorts hospitalized for COVID-19. We retrospectively evaluated all consecutive admitted without exclusion criteria. Suspect was defined according current guidelines. Age, sex, in-hospital death, length stay, comorbidities, serum...
Venous thromboembolism (VTE), encompassing both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a leading cause of morbidity mortality worldwide.GARFIELD-VTE prospective, non-interventional observational study real-world treatment practices. We aimed to capture the 36-month clinical outcomes 10,679 patients with objectively confirmed VTE enrolled between May 2014 January 2017 from 415 sites in 28 countries.A total 6582 (61.6 %) had DVT alone, 4097 (38.4 PE ± DVT. At baseline, 98.1...