- Dialysis and Renal Disease Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vector-borne infectious diseases
- Renal Diseases and Glomerulopathies
- Viral Infections and Vectors
- Muscle and Compartmental Disorders
- Acute Kidney Injury Research
- IgG4-Related and Inflammatory Diseases
- Ion Transport and Channel Regulation
- Ion channel regulation and function
- Chronic Kidney Disease and Diabetes
- Mechanical Circulatory Support Devices
- Electrolyte and hormonal disorders
- Renal Transplantation Outcomes and Treatments
- Multiple Myeloma Research and Treatments
- Foreign Body Medical Cases
- Liver Disease and Transplantation
- Dermatological diseases and infestations
- Systemic Lupus Erythematosus Research
- Peptidase Inhibition and Analysis
- Cardiac electrophysiology and arrhythmias
- Hemostasis and retained surgical items
- Pneumocystis jirovecii pneumonia detection and treatment
- Pancreatic and Hepatic Oncology Research
- Complement system in diseases
Staten Island University Hospital
2012-2025
Northwell Health
2017-2024
Feinstein Institute for Medical Research
2024
Hypokalemic periodic paralysis (HPP) presents a diagnostic challenge due to the painless muscle weakness it causes. This case discusses patient with HPP along electrocardiogram (ECG) findings of Brugada phenocopies (BrP) in setting hypokalemia. A review literature showed that is seventh documented example BrP induced by hypokalemia alongside HPP. 43-year-old man presented emergency department lower limb weakness. He attributed his symptoms substantial meal consumed after breaking Ramadan...
Leptospirosis has recently come to international attention as a globally important re-emerging infectious disease. Our case is unusual given the season, location and setting in which leptospirosis occurred. According New York City Board of Health, there were only two other cases year that our patient was diagnosed. A 49-year-old healthy Chinese man presented hospital with sepsis multiorgan failure. The did not respond antibiotics his failure worsened. His workup show any significant findings...
Immune checkpoint blockade therapy is gaining popularity among oncologists for treatment of solid and hematologic malignancies. The widespread use these agents resulted in increasing incidence renal immune-related adverse events. Reported toxicity described so far includes acute interstitial nephritis, minimal change disease, immune complex glomerulonephritis. We report the case a 79-year-old female with metastatic non-small cell lung cancer on anti-PD-1 nivolumab. After 4th administration...
Patients with chronic kidney disease (CKD) are three times more likely to have myocardial infarction (MI) and suffer from increased morbidity higher mortality. Traditional unique risk factors prevalent constitute challenges for the standard of care. However, CKD patients been largely excluded clinical trials little evidence is available guide evidence-based treatment coronary artery in CKD. Our objective was assess whether a difference exists management MI (ST-segment elevation...
Background Normal saline solution (NSS) has been the fluid of choice for renal transplant patients, but it can lead to hyperchloremic acidosis and hyperkalemia. This study was performed compare safety profile low-chloride solutions with that NSS in patients. Methods We conducted a systemic review search on PubMed, Embase, Central Cochrane Registry. Randomized clinical trials (RCTs) matched cohort studies involving as control arm an intervention were chosen. The standardized mean difference...
We report a case of 71-year-old Filipino female who was admitted to the hospital for abdominal pain, vomiting and diarrhea 8 days duration. The patient found have marked acute kidney injury (AKI), which required hemodialysis in next 3 days. Extensive workup revealed hematuria, subnephrotic range proteinuria, elevated anti-nuclear antibody (ANA) total immunoglobulin G (IgG) levels, with normal IgG4 anti-dsDNA levels. On biopsy, mild membranous glomerulonephritis found, along autoimmune...
Immunoglobulin D (IgD) multiple myeloma (MM) is a very rare form of affecting less than 2% all patients. It has multiorgan involvement with renal failure being the key feature. We present here case IgD MM in 62-year-old white male, smoker past medical history hypertension, who presented to emergency department complaints lower abdominal pain, constipation and decreased urination. Physical exam was unremarkable. Laboratory investigation showed S.Cr 5.99 mg/dL, hemoglobin 8.7 g/dL corrected...
Background: Hemodialysis patients are exposed to blood and products more than the general population also at higher risk for hepatitis B (HB) contamination. For these reasons, it is highly recommended that this patient gets HB vaccine. The efficacy of vaccine measured by measuring titers antibody in serum patient. A minimum titer 10 mIU/mL considered be a response. conversion rate hemodialysis ranges from 50% 80%, as compared where over 95%. As opposed population, end-stage renal on do not...
Critically ill patients receive a significant amount of fluids leading to positive fluid balance; this dilutes serum creatinine resulting in an overestimated glomerular filtration rate. The goal our study is identify undiagnosed or underestimated acute kidney injury (AKI) the intensive care unit (ICU). It will also morbidity and mortality associated with AKI. We reviewed records admitted institution (Staten Island University Hospital) between 2012 2013 for more than 2 days. Patients end...
Purpose Acute kidney injury (AKI) is a significant cause of morbidity and mortality post cardiac surgery sometimes requiring intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration (CVVH). Previous studies included only procedures utilizing cardiopulmonary bypass (CPB). We reviewed CPB non-CPB patients who developed AKI required CVVH versus no CVVH. Materials Methods 141 undergoing adult AKI. 70 (group1) 71 did not (group2). compared 30 day mortality, renal recovery,...
Collapsing focal segmental glomerulosclerosis (cFSGS) and tubuloreticular inclusions (TRIs) are pathological findings that described more in the setting of lupus nephritis. However, these two entities not a part p...
Immunological phenomena have been described in infections such as infective endocarditis. However, none has reported the context of Babesiosis. Babesiosis is a tick-borne illness caused by protozoa genus Babesia and causes that range from asymptomatic to severe sometimes are fatal. This report presents first case ANCA/ANA positive babesiosis an asplenic patient treated with repeated red blood cell exchange transfusion.
Post-infectious glomerulonephritis (PIGN) usually occurs within few days to weeks following an infection. Clinical presentation is variable, but in general, it considered a benign entity with good prognosis. It rarely requires kidney biopsy confirm the diagnosis. We present case of 55-year-old, previously healthy, male who presented for worsening shortness breath, persistent cough, and right-sided pleuritic chest pain. Initial workup revealed right exudative effusion empyema. Hospital course...
Foreign body ingestion is common, although perforation after rare. We report a case of an ingested sharp wooden stick that perforated the proximal jejunum toward renal vasculature, causing segmental artery thrombosis and infarct. The patient presented with severe abdominal pain vomiting. A computed tomography scan revealed linear opacity corresponding to foreign body. was removed endoscopically through deep-push enteroscopy rat-tooth forceps. this unique by left kidney, which managed endoscopically.
Background: Guillain-Barré syndrome (GBS) is an autoimmune disease damaging the peripheral nervous system. It commonly presents as rapidly progressing bilateral symmetrical motor weakness. There has been known association of inappropriate antidiuretic hormone (SIADH) in patients with GBS though it rare. Case Presentation: We report a patient rare clinical presentation SIADH before onset deficits GBS. Conclusions: initial finding very This case emphasizes importance early detection to avoid...
C3 glomerulonephritis is rare form of membranoproliferative glomerulonephritis, which result from defects in complement regulatory proteins that promotes excessive activation alternative pathway. Kidney disease common complication multiple myeloma (MM). Most renal complications MM include monoclonal immunoglobulin deposition and cast nephropathy. Moreover, Ig, through the interference pathway has been shown to play synergistic role towards damage. Up 50% patients present with impairment at...
The co-occurrence of acute kidney injury secondary to rhabdomyolysis in a young patient can present as prognostic and therapeutic challenge. Here we report case with an unusually high creatinine phosphokinase over 500,000 U/L after 2-hour workout session at the gym. challenge was assess if need for renal replacement therapy warranted whether IV fluid close monitoring would be enough treat him, given he had good urine output no acid base disorder. literature is reviewed attempt delineate...
A 38-year-old African American woman previously healthy presented to the emergency department with 3-day history of increasing Left Upper Quadrant (LUQ) severe pain radiating left flank fever and persistent vomiting. The patient had no diarrhea, constipation, or bloody stools. Fever LUQ tenderness were noted on exam. She normal white count, mildly elevated liver enzymes, creatinine, lipase lactic acid. Urinalysis showed leukocytes, RBC, negative nitrites trace protein. On CT-scan abdomen, a...