A5016304706- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Metastasis and carcinoma case studies
- Ovarian cancer diagnosis and treatment
- Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Colorectal Cancer Treatments and Studies
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Cancer, Lipids, and Metabolism
- Cancer Immunotherapy and Biomarkers
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Renal cell carcinoma treatment
- Lung Cancer Treatments and Mutations
- Frailty in Older Adults
- Autoimmune and Inflammatory Disorders
- Hidradenitis Suppurativa and Treatments
- Inflammation biomarkers and pathways
- Perfectionism, Procrastination, Anxiety Studies
Nara Medical University
2019-2024
Hokkaido University
2024
Nara Medical University Hospital
2022
Yokohama City University
2021
Nara Prefectural Institute of Public Health Research Center
2014-2017
Kagawa Prefectural Central Hospital
2017
Kobe Central Hospital
2017
Gojo (France)
2014
Primary tumor location of colon cancer has been reported to affect the prognosis after curative resection. However, some reports suggested impact was varied by stage. This study analyzed prognostic sidedness in stages II, III, and liver metastasis resection using propensity-matched analysis.Right-sided defined as a located from cecum splenic flexure, while any more distal left-sided cancer. Patients who underwent at Nara Medical University hospital between 2000 2016 were analyzed.There 110...
H2O–N2 coelectrolysis by protonic solid oxide cells (H+-SOCs) holds great promise as it enables the sustainable production of pure ammonia gas from air and water through renewable electricity. This investigation highlights exceptional hydrogen ion diffusivity limited evolution reaction (HER) activity VN0.9, establishing a valuable cathode material for H+-SOCs. The model were fabricated sputter-depositing dense VNx film (x = 0.9 1.1) on BaZr0.4Ce0.4Y0.1Yb0.1O3-δ (BZCYYb4411) bulk proton...
Background Postoperative delirium was reported to be associated with increased postoperative mortality after liver resection. Therefore, it is crucial prevent in such cases. Ramelteon, an agonist of melatonin receptor has been suggested useful for preventing delirium. The aim this study examine whether ramelteon effective at elective Methods cases patients who underwent resection Nara Medical University (Nara, Japan) between January 2014 and August 2018 were analyzed. During the period from...
We previously reported that pentagamavunone-1 (PGV-1) effectively inhibited cell proliferation in many types of human tumors, including pancreatic cancer, by inducing M phase (prometaphase) arrest, senescence, and apoptosis with few side effects. However, a detailed evaluation the effects PGV-1 on cancer cells an vivo setting has not yet been conducted. The present study investigated potential efficacy as both monotherapy combination therapy for using multiple xenograft mouse assays. A...
Skeletal muscle metastasis from gastric cancer is extremely rare and often accompanied with synchronous to any other organs. We herein report a case of rapidly developing multiple skeletal metastases without organ metastases. A 47-year-old man underwent distal gastrectomy for advanced cancer. Pathological diagnosis was poorly differentiated adenocarcinoma, T2N1M0, Stage IIA. The patient presented history left dorsal tenderness 12 months after the operation. computed tomography (CT) revealed...
Background/Aim: The aim of this study was to evaluate whether modern chemotherapy has changed characteristics actual five-year survivors after liver resection for colorectal metastasis (CRLM). Patients and Methods: records 210 patients, who underwent curative CRLM at our institution between January 1990 May 2014, were reviewed. patients treated before 2004 when not introduced compared with the 2005. Results: Actual survivor rates significantly higher 2005 (33.3% vs. 49.0%, p=0.022)....
Objective This study investigated the impact of surgical margin (SM) on prognosis and recurrence intrahepatic cholangiocarcinoma (ICC). Summary background data The SM remains controversial. Methods We analyzed 58 ICC patients who underwent macroscopically curative surgery. were classified into 5 categories according to SM; microscopically positive (R1), 0 <1 mm, 1 <5 <10 ≥10 mm. overall survival (OS) rate was significantly different for mm or ≥1 mm; therefore, cutoff...
症例は58歳，男性．8年前に胃癌に対し胃全摘術を施行，pT2（SS），pN1，H0，P0，CY0，Stage II，組織型は印環細胞癌を含む低分化腺癌であった．2010年9月より便秘を訴え，当科を受診した．注腸造影検査および下部消化管内視鏡検査で，横行結腸脾彎曲部への転移を認め，化学療法の後に手術を施行した．開腹所見では横行結腸脾彎曲部に腫瘍が存在し，浸潤があった空腸・脾臓・横隔膜を合併切除した．病理組織学的検査所見で結腸の粘膜下層から漿膜下組織を中心に低分化腺癌を認め，組織型が一致していることより，胃原発，linitis plastica型大腸転移と診断した．転移性大腸癌は通常のスクリーニング検査では診断できないことが多いが切除可能症例では長期予後が望めるという報告もある．自験例のような晩期転移再発を考慮に入れたフォローアップを行い，可能であれば積極的に手術を行う意義があると考えられる．
Restrictive pulmonary dysfunction (RPD) is a risk factor for perioperative complications during gastrointestinal surgery. We hypothesized that high airway pressure due to RPD results in increased intraoperative blood loss liver Thus, we investigated the effects of on outcomes resection.This study included 496 patients who underwent curative resection at our hospital between April 2009 and 2020. Perioperative control groups were compared. was defined as % vital capacity <80%.Forty-one (8.3%)...
症例は54歳，女性．海外旅行中に腹痛を自覚し，医療機関を受診．現地で急性虫垂炎と診断され，開腹虫垂切除術を受けた．帰国後，術後4日目から発熱と腹痛を認め，近医を受診し，汎発性腹膜炎の疑いにて当科に紹介となった．腹部造影CT検査では，大網脂肪織の混濁と心嚢液，胸腹水貯留を認めた．このため大網脂肪織炎と診断し，腹膜刺激症状を強く認めたため，緊急手術を施行した．開腹すると漿液性腹水を，さらに大網の著明な腫大と硬化を認めた．また，虫垂断端部に異常は確認できなかった．このため大網が炎症の主座と判断し，大網切除，腹腔ドレナージ術を施行した．病理組織学的検査では，大網に強い好中球浸潤とフィブリン析出を認め，大網脂肪織炎に矛盾しない所見であった．術後経過は良好で約2週間で退院となった．大網原発の脂肪織炎の報告例は散見される程度しか存在せず，手術直後に発症した症例は稀である．文献的考察を加えて報告する．
症例は75歳の男性で，5年前に腹痛を主訴に近医を受診し，虚血性腸炎の診断で入院加療となった．入院時の腹部CTで，門脈直下での上腸間膜静脈の閉塞を指摘されていたが，原疾患の改善後は経過観察となっていた．1年前から吐下血を反復するようになり，上下部消化管内視鏡検査を施行するも出血源が同定できず，精査加療目的に当院内科へ紹介となった．腹部CTで上腸間膜静脈の閉塞と十二指腸水平脚に著明な静脈瘤を認め，主出血源と考えられた．最大径の回盲部の動静脈奇形に対してコイル塞栓術を施行したが，顕性の下血が持続し，手術加療目的に当科へ紹介となった．出血部位の切除と門脈の減圧を目的に，膵頭十二指腸切除術，回盲部切除術，上腸間膜静脈閉塞部切除，右外腸骨静脈グラフト間置による血行再建を施行した．術後1年半の経過で消化管出血の再燃は認めていない．過去に同様の報告例を認めず報告する．