Atsushi Yoshimura

ORCID: 0000-0003-1995-8190
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Rice Cultivation and Yield Improvement
  • GABA and Rice Research
  • Plant Disease Resistance and Genetics
  • Plant Pathogenic Bacteria Studies
  • Plant Reproductive Biology
  • Plant Molecular Biology Research
  • Plant-Microbe Interactions and Immunity
  • Chromosomal and Genetic Variations
  • Alcohol Consumption and Health Effects
  • Pancreatic function and diabetes
  • Plant responses to water stress
  • Substance Abuse Treatment and Outcomes
  • Wheat and Barley Genetics and Pathology
  • Plant Pathogens and Fungal Diseases
  • Plant Virus Research Studies
  • Genetics and Plant Breeding
  • Plant Genetic and Mutation Studies
  • Gastrointestinal disorders and treatments
  • Organ Transplantation Techniques and Outcomes
  • Photosynthetic Processes and Mechanisms
  • Nematode management and characterization studies
  • Glycosylation and Glycoproteins Research
  • Muscle Physiology and Disorders
  • Alcoholism and Thiamine Deficiency

Shiga University of Medical Science
2007-2025

Kyushu University
2015-2024

National Archives and Records Administration
2019-2024

Chuo University
2022-2024

Shiga University
2024

Nutrasource
1994-2023

Nara Medical University
1993-2023

Tohoku Medical and Pharmaceutical University
2016-2023

Hokkaido University
2021-2023

Kurihama Medical and Addiction Center
2013-2022

Two evolutionarily distant plant species, rice (Oryza sativa L.), a short-day (SD) plant, and Arabidopsis thaliana, long-day share conserved genetic network controlling photoperiodic flowering. The orthologous floral regulators-rice Heading date 1 (Hd1) CONSTANS (CO)-integrate circadian clock external light signals into mRNA expression of the FLOWERING LOCUS T (FT) group inducer. Here, we report that Early heading (Ehd1) gene, which confers SD promotion flowering in absence functional allele...

10.1101/gad.1189604 article EN Genes & Development 2004-04-12

We have characterized a rice (Oryza sativa) dwarf mutant, dwarf11 (d11), that bears seeds of reduced length. To understand the mechanism by which seed length is regulated, D11 gene was isolated map-based cloning method. The found to encode novel cytochrome P450 (CYP724B1), showed homology enzymes involved in brassinosteroid (BR) biosynthesis. phenotype d11 mutants restored application brassinolide (BL). Compared with wild-type plants, aberrant mRNA accumulated at higher levels and...

10.1105/tpc.104.024950 article EN The Plant Cell 2005-02-10

A rice Dwarf 1 gene was identified by using a map-based cloning strategy. Its recessive mutant allele confers dwarf phenotype. Linkage analysis revealed that cDNA encoding the alpha-subunit of GTP-binding protein cosegregated with d1 in 3,185 segregants. Southern hybridization this as probe showed different band patterns several lines. In at least four independent mutants, no transcript observed Northern analysis. Sequencing an 833-bp deletion had occurred one alleles, which resulted...

10.1073/pnas.96.18.10284 article EN Proceedings of the National Academy of Sciences 1999-08-31

Unlike maize and wheat, where artificial selection is associated with an almost uniform increase in seed or grain size, domesticated rice exhibits dramatic phenotypic diversity for size shape. Here we clone characterize GS3, evolutionarily important gene controlling rice. We show that GS3 highly expressed young panicles both short- long-grained varieties but not leaves after flowering, use genetic transformation to demonstrate the dominant allele short complements long-grain phenotype. An...

10.1534/genetics.109.103002 article EN Genetics 2009-06-10

Epigenetic mutations confer heritable changes in gene expression that are not due to the underlying sequence of DNA. We identified a spontaneous rice mutant, Epi-d1, shows metastable dwarf phenotype. The phenotype is mitotically and meiotically inheritable corresponds epigenetic silencing DWARF1 (D1) gene. silenced state correlated with repressive histone DNA methylation marks D1 promoter region but associated alterations. Compared other known loci plants such as paramutable maize alleles...

10.1073/pnas.0901942106 article EN Proceedings of the National Academy of Sciences 2009-06-19

We have constructed a genetic map of the nuclear genome in rice (Oryza sativa L.), utilizing 322 restriction fragment length polymorphism (RFLP) DNA markers and nine morphologlcal biochemical genetlc markers. The RFLP is based on segregation 144 F2 plants from cross between Indica Japonica varieties. covers total 1, 836 cM with 347 loci exceeds data recorded classical by 58.5% current (McCOUCH et al. 1988) 32.2%. linkage groups were assigned to twelve chromosomes using trisomic mutants...

10.1270/jsbbs1951.41.665 article EN Ikushugaku zasshi 1991-01-01

Hybrid incompatibility in F(1) hybrids or later generations is often observed as sterility inviability. This acts postzygotic reproductive isolation, which results the irreversible divergence of species. Here, we show that reciprocal loss duplicated genes encoding mitochondrial ribosomal protein L27 causes hybrid pollen cultivated rice Oryza sativa and its wild relative O. glumaepatula. Functional analysis revealed this gene essential for stage development, distribution suggests duplication...

10.1073/pnas.0908283107 article EN Proceedings of the National Academy of Sciences 2010-01-04

During early chloroplast differentiation, the regulation of plastid genetic system including transcription and translation differs greatly from that in mature chloroplast, suggesting existence a stage-dependent mechanism regulates during this period. The virescent-1 (v(1)) mutant rice (Oryza sativa) is temperature-conditional develops chlorotic leaves under low-temperature conditions. We reported previously leaf chlorosis v(1) caused by blockage activation development. Here we identify V(1)...

10.1111/j.1365-313x.2011.04755.x article EN The Plant Journal 2011-08-31

Significance This study investigates a previously unidentified cysteine-rich peptide (CRP). CRPs have diverse roles in plant growth and development, such as control of stomata density guidance pollen-tube elongation. Despite numerous studies on Arabidopsis thaliana , there are still many peptides with unknown function. We identify rice CRP named Regulator Awn Elongation 2 (RAE2) show that it is cleaved specifically the spikelet to promote awn demonstrate RAE2 was target selection during...

10.1073/pnas.1604849113 article EN Proceedings of the National Academy of Sciences 2016-07-27

Chromosome substitution series are useful tools for precise mapping of quantitative trait loci (QTLs) and the evaluation gene action as a single factor or in case interactions. In this study, we produced reciprocal sets chromosome segment lines (CSSLs) between Asominori (Japonica) IR24 (Indica) cultivated rice, Oryza sativa L. A set carries few donor segments overlapping with neighboring uniform genetic background. Reciprocal were developed by repeated backcrossing to respective recurrent...

10.1270/jsbbs.52.319 article EN Breeding Science 2002-01-01

Summary Guanylate kinase (GK) is a critical enzyme in guanine nucleotide metabolism pathways, catalyzing the phosphorylation of (d)GMP to (d)GDP. Here we show that novel gene, VIRESCENT 2 ( V2 ), encodes new type GK (designated pt/mtGK) localized plastids and mitochondria. We initially identified gene by positional cloning rice v2 mutant. The mutant temperature‐sensitive develops chlorotic leaves at restrictive temperatures. mutation causes inhibition chloroplast differentiation; particular,...

10.1111/j.1365-313x.2007.03251.x article EN The Plant Journal 2007-08-28

IL-17-producing CD4+ T cells, so called Th17 constitute a newly identified inflammatogenic cell population, which is critically involved in some inflammatory diseases. To explore the role of cells murine experimental autoimmune uveoretinitis (EAU), model human uveitis where Th1 responses predominantly participate pathogenesis, IL-17−/− mice were immunized with interphotoreceptor retinoid-binding protein peptide 1–20 for disease induction. Funduscopic examination revealed that EAU was induced...

10.1093/intimm/dxm135 article EN International Immunology 2007-12-21

Objective The potential influence of the multidrug resistance 1 (MDR1) gene and cytochrome P450 (CYP) genes, CYP3A4 CYP3A5, on oral clearance (CL/F) tacrolimus in adult living-donor liver transplant patients was examined. Furthermore, development renal dysfunction analyzed relation to CYP3A5 genotype. Methods Sixty de novo receiving were enrolled this study. effects various covariates (including intestinal hepatic mRNA levels MDR1 CYP3A4, measured each tissue taken at time transplantation,...

10.1097/fpc.0b013e3282f9ac01 article EN Pharmacogenetics and Genomics 2008-05-01

The brown planthopper (BPH), Nilaparvata lugens (Stål), is one of the most serious and destructive pests rice, can be found throughout rice-growing areas Asia. To date, more than 24 major BPH-resistance genes have been reported in several Oryza sativa ssp. indica cultivars wild relatives. Here, we report genetic basis high level BPH resistance derived from an Indian rice cultivar, ADR52, which was previously identified as resistant to whitebacked (Sogatella furcifera [Horváth]). An F(2)...

10.1007/s00122-011-1723-4 article EN cc-by-nc Theoretical and Applied Genetics 2011-11-02

Floods impede gas (O2 and CO2 ) exchange between plants the environment. A mechanism to enhance plant under water comprises films on hydrophobic leaves, but genetic regulation of this is unknown. We used a rice mutant (dripping wet leaf 7, drp7) which does not retain its wild-type (Kinmaze), in gene discovery for trait. Gene complementation was tested transgenic lines. Functional properties leaves as related film retention underwater photosynthesis were evaluated. Leaf Gas Film 1 (LGF1)...

10.1111/nph.15070 article EN publisher-specific-oa New Phytologist 2018-03-02

Recombinant inbred (RI) Iines of rice (Oryza sativa L.) were developed from a cross Asominori x IR24 by the single seed descent method. Seventy-one RI F6 and F7 generations used for RFLP mapping. framework map constructed using lines covered distance 1275cM containing 375 markers. All twelve linkage groups assigned to their respective chromo-somes. The showed distorted segregation in some regions chromosomes 1, 3, 6, 11 12. Heterozygous loci still remained. Average frequency heterozygous...

10.1270/jsbbs1951.46.279 article EN Ikushugaku zasshi 1996-01-01

Stigma exsertion is an important trait that contributes to the improvement of seed production in hybrid rice. We demonstrate GS3, one genes regulating length, also regulates stigma length and participates GS3 mRNA expressed basal part young stigma, a nonsense mutation second exon causes increase cell number, resulting elongation stigma. Manipulation should contribute seed-production efficiency.

10.1270/jsbbs.61.244 article EN Breeding Science 2011-01-01

Enhanced recovery after surgery (ERAS) protocols may reduce postoperative complications and the length of hospital stay. Studies effectiveness ERAS should include not only doctor-reported outcomes, but also patient-reported in order to better estimate their impact on recovery. However, outcomes are commonly reported. Thus, it needs be assessed whether early discharge from is compatible with a outcome viewpoint patients themselves.The 40-item quality score (QoR-40) recovery-specific,...

10.1186/s12885-015-1799-3 article EN cc-by BMC Cancer 2015-10-26

Abstract Reproductive barriers are commonly observed in both animals and plants, which they maintain species integrity contribute to speciation. This report shows that a combination of loss-of-function alleles at two duplicated loci, DUPLICATED GAMETOPHYTIC STERILITY 1 (DGS1) on chromosome 4 DGS2 7, causes pollen sterility hybrid progeny derived from an interspecific cross between cultivated rice, Oryza sativa, Asian annual wild O. nivara. Male gametes carrying the DGS1 allele nivara...

10.1534/g3.117.043943 article EN cc-by G3 Genes Genomes Genetics 2017-06-08
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