Masahiko Kawaguchi

ORCID: 0000-0003-1830-0020
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About
Contact & Profiles
Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Intensive Care Unit Cognitive Disorders
  • Airway Management and Intubation Techniques
  • Nausea and vomiting management
  • Spine and Intervertebral Disc Pathology
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Enhanced Recovery After Surgery
  • Neurosurgical Procedures and Complications
  • Hemodynamic Monitoring and Therapy
  • Respiratory Support and Mechanisms
  • Thermal Regulation in Medicine
  • Tracheal and airway disorders
  • Spinal Fractures and Fixation Techniques
  • Cardiac Ischemia and Reperfusion
  • Hip and Femur Fractures
  • Cardiac Arrest and Resuscitation
  • Thyroid and Parathyroid Surgery
  • Acute Kidney Injury Research
  • Pain Management and Opioid Use
  • Cerebrovascular and Carotid Artery Diseases
  • Meningioma and schwannoma management

Nara Medical University
2016-2025

Nara Medical University Hospital
1998-2023

Chiba Institute of Technology
2022-2023

Advanced Engineering (Czechia)
2023

Clinical Orthopaedics and Related Research
2019

Kanazawa University
1998-2013

National Defense Medical College
2008-2009

Fukui-ken Saiseikai Hospital
2007

Marymount University
2002-2005

American Association of Neuropathologists
2005

Constant-voltage and constant-current stimulators may be used for transcranial electrical stimulation of motor evoked potentials (TES-MEP). However, no previous report has determined whether the two monophasic methods lead to similar responses during intra-operative monitoring. We studied differences in lateralities compound muscle action (CMAPs) spinal cord monitoring via TES-MEP using constant-voltage stimulations. CMAPs were bilaterally recorded from upper lower limb muscles 95 patients...

10.1038/s41598-019-39883-y article EN cc-by Scientific Reports 2019-03-07

Background/Objectives: The aim was to develop a Japanese version of the Obstetric Quality Recovery-11 questionnaire (ObsQoR-11J), assess its feasibility, reliability, and validity, investigate association with postpartum depression functionality. need for this study is underscored by limited availability ObsQoR-11 in different languages lack documentation on associations early recovery mid-term patient-reported outcomes. Methods: After translating ObsQoR-11J into Japanese, 138 patients who...

10.3390/jcm14041390 article EN Journal of Clinical Medicine 2025-02-19

Background Several investigations have shown that volatile anesthetics can reduce ischemic cerebral injury. In these studies, however, neurologic injury was evaluated only after a short recovery period. Recent data suggest caused by ischemia is dynamic process characterized continual neuronal loss for prolonged Whether isoflurane-mediated neuroprotection sustained longer period not known. The current study conducted to compare the effect of isoflurane on brain (2-day) and long (14-day)...

10.1097/00000542-200005000-00023 article EN Anesthesiology 2000-05-01

In Brief Although isoflurane can reduce ischemic neuronal injury after short postischemic recovery intervals, this neuroprotective efficacy is not sustained. Neuronal apoptosis contribute to the gradual increase in infarct size ischemia. This suggests that isoflurane, although capable of reducing early death, may inhibit ischemia-induced apoptosis. We investigated effects on markers rats subjected focal Fasted Wistar-Kyoto were anesthetized with and randomly allocated awake (n = 40) or...

10.1213/01.ane.0000105872.76747.f6 article EN Anesthesia & Analgesia 2004-03-01

Enhanced recovery after surgery (ERAS) protocols may reduce postoperative complications and the length of hospital stay. Studies effectiveness ERAS should include not only doctor-reported outcomes, but also patient-reported in order to better estimate their impact on recovery. However, outcomes are commonly reported. Thus, it needs be assessed whether early discharge from is compatible with a outcome viewpoint patients themselves.The 40-item quality score (QoR-40) recovery-specific,...

10.1186/s12885-015-1799-3 article EN cc-by BMC Cancer 2015-10-26

Modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA) provides wide analgesic range. Herein, we examined the quality of recovery (QoR) M-TAPA for total laparoscopic hysterectomy (TLH) compared with oblique subcostal transversus abdominis plane (OSTAPB) and measured plasma levobupivacaine concentrations (PClevo). Forty female patients undergoing TLH were randomized to each group. Nerve blocks performed bilaterally 25 mL 0.25% administered per side. The primary...

10.3390/jcm13030712 article EN Journal of Clinical Medicine 2024-01-25

Abstract Background Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) was first described as a peripheral nerve by Tulgar in 2019. This technique provides an analgesic effective range from Th7–11 with single puncture per side. Although the efficacy and duration of M-TAPA have been reported, further examination is required. Therefore, this study aimed to evaluate open gynecologic surgery. Methods Following approval, 10 adult female patients scheduled for radical...

10.1186/s12871-022-01652-2 article EN cc-by BMC Anesthesiology 2022-04-15

Aim Elderly patients undergoing abdominal surgery have a high risk of developing postoperative delirium. This study aimed to explore factors for delirium by focusing on preoperative hematologic markers, and develop model that would be useful in predicting the occurrence Methods retrospective included aged ≥65 years who underwent elective under general anesthesia from January 2017 May 2019. Patients' demographics, data intraoperative were recorded. Neutrophil‐to‐lymphocyte ratio,...

10.1111/ggi.14066 article EN Geriatrics and gerontology international/Geriatrics & gerontology international 2020-10-21

Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiomyocyte death and precipitate life-threatening heart failure. Propofol has been proposed protect cells or tissues against oxidative stress. However, the mechanisms underlying its beneficial effects are not fully elucidated. In present study, we employed an in vitro injury model, rat cardiac H9c2 were treated with H2O2, investigated roles of propofol treatment reduced H2O2-induced apoptotic cell death....

10.1371/journal.pone.0196191 article EN cc-by PLoS ONE 2018-04-24

Ki-67, cytokeratin 13, and/or 17 detection by immunohistochemistry has been reported to be useful for the diagnosis of oral precancerous lesions. However, use these markers remains controversial because lack appropriately designed statistical studies. We assessed hypothesis that or could facilitate lesions predict prognosis.Epithelial dysplasia was classified as low grade (none mild dysplasia) high (moderate dysplasia, severe carcinoma in situ). This study included 58 low-grade and 36...

10.1111/jop.12262 article EN Journal of Oral Pathology and Medicine 2014-09-22
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