Tomoyuki Furuta

ORCID: 0000-0002-0869-6626
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Glioma Diagnosis and Treatment
  • Rice Cultivation and Yield Improvement
  • GABA and Rice Research
  • Genomics and Phylogenetic Studies
  • Plant Disease Resistance and Genetics
  • Plant Molecular Biology Research
  • Anesthesia and Neurotoxicity Research
  • Cell Adhesion Molecules Research
  • Ultrasound and Hyperthermia Applications
  • S100 Proteins and Annexins
  • Plant Stress Responses and Tolerance
  • Genetics and Plant Breeding
  • Brain Metastases and Treatment
  • Pituitary Gland Disorders and Treatments
  • Plant Reproductive Biology
  • Protease and Inhibitor Mechanisms
  • MRI in cancer diagnosis
  • Peptidase Inhibition and Analysis
  • Infrared Thermography in Medicine
  • Mitochondrial Function and Pathology
  • Cancer Treatment and Pharmacology
  • Photosynthetic Processes and Mechanisms
  • Plant nutrient uptake and metabolism
  • Microtubule and mitosis dynamics

Okayama University
1988-2024

Nagoya University
2009-2023

Sunagawa City Medical Center
2021

AndroScience (United States)
2014

Kariya Toyota General Hospital
2011

Kindai University Hospital
2008

Mie Chuo Medical Center
2008

Kyoto Pharmaceutical University
2005

Mie University Hospital
2005

Chiba Hokusou Hospital
1999

Significance Grain weight is an important crop yield component; however, its underlying regulatory mechanisms are largely unknown. Here, we identify a grain-weight quantitative trait locus (QTL) in rice encoding new-type GNAT-like protein that harbors intrinsic histone acetyltransferase activity (OsglHAT1). Elevated OsglHAT1 expression enhances grain and by enlarging spikelet hulls via increasing cell number accelerating filling, increases global acetylation levels of H4. Our findings reveal...

10.1073/pnas.1421127112 article EN Proceedings of the National Academy of Sciences 2014-12-22

How rice defeats the floodwaters Deepwater varieties grow taller when flooded, in a growth response driven by plant hormones gibberellin and ethylene. This keeps leaves above water. Kuroha et al. identified genes underlying this phenotype, which encode component of biosynthetic pathway its regulatory ethylene-responsive transcription factor. genetic relay drives stem internodes to flooding. Modern cultivated deepwater rice, has been domesticated for adaptation monsoon season Bangladesh,...

10.1126/science.aat1577 article EN Science 2018-07-13

Significance This study investigates a previously unidentified cysteine-rich peptide (CRP). CRPs have diverse roles in plant growth and development, such as control of stomata density guidance pollen-tube elongation. Despite numerous studies on Arabidopsis thaliana , there are still many peptides with unknown function. We identify rice CRP named Regulator Awn Elongation 2 (RAE2) show that it is cleaved specifically the spikelet to promote awn demonstrate RAE2 was target selection during...

10.1073/pnas.1604849113 article EN Proceedings of the National Academy of Sciences 2016-07-27

The G-quadruplexes form highly stable nucleic acid structures, which are implicated in various biological processes both DNA and RNA. Although have been studied great detail, roles of RNA received less attention. Here, a screening chemical library permitted identification small-molecule tool that binds selectively to G-quadruplex structures. polyaromatic molecule, RGB-1, stabilizes G-quadruplex, but not versions or other RGB-1 intensified the G-quadruplex-mediated inhibition translation...

10.1021/jacs.6b04506 article EN Journal of the American Chemical Society 2016-07-14

Abstract Rapid and cost-effective genotyping of large mapping populations can be achieved by sequencing a reduced representation the genome every individual in given population, using that information to generate genetic markers. A customized genotyping-by-sequencing (GBS) pipeline was developed genotype rice F2 population from cross Oryza sativa ssp. japonica cv. Nipponbare African wild species O. longistaminata. While most GBS pipelines aim analyze mainly homozygous populations, we...

10.1534/g3.116.038190 article EN cc-by G3 Genes Genomes Genetics 2017-03-01

The wild relatives of rice (Oryza sativa L.) are useful sources alleles that have evolved to adapt in diverse environments around the world. Oryza rufipogon, known progenitor cultivated rice, harbors genes been lost varieties through domestication or evolution. This makes O. rufipogon an ideal source value-added traits can be utilized improve existing cultivars. To explore potential as a genetic resource for improving sativa, 33 chromosome segment substitution lines (CSSLs) (W0106)...

10.1270/jsbbs.63.468 article EN Breeding Science 2014-01-01

Abstract The African wild rice species Oryza longistaminata has several beneficial traits compared to cultivated species, such as resistance biotic stresses, clonal propagation via rhizomes, and increased biomass production. To facilitate breeding efforts functional genomics studies, we de-novo assembled a high-quality, haploid-phased genome. Here, present our assembly, with total length of 351 Mb, which 92.2% was anchored onto 12 chromosomes. We detected 34,389 genes 38.1% the genome...

10.1038/s42003-018-0171-y article EN cc-by Communications Biology 2018-10-01

Sudden sensorineural hearing loss (SSNHL) and Ménière's disease are the most common inner ear diseases in which causes unknown. As recent magnetic resonance imaging has demonstrated disruption of blood–labyrinth barrier these diseases, inflammatory reaction associated with increased permeability blood vessels may be involved. The genotypes interleukin 1A (IL1A) (−889C/T; rs1800587) 1B (IL1B) (−511C/T; rs16944) were determined using an allele-specific primer–polymerase chain method 72...

10.1111/j.1744-313x.2011.01004.x article EN International Journal of Immunogenetics 2011-03-09

A long awn is one of the distinct morphological features wild rice species. This organ thought to aid in seed dispersal and prevent predation by animals. Most cultivated varieties Oryza sativa glaberrima, however, have lost ability form awns. The causal genetic factors responsible for loss these two species remain largely unknown. Here, we evaluated three sets chromosome segment substitution lines (CSSLs) a common O. background (cv. Koshihikari) that harbor genomic fragments from nivara,...

10.1534/g3.115.020834 article EN cc-by G3 Genes Genomes Genetics 2015-09-16

DNA marker-assisted selection (MAS) has become an indispensable component of breeding. Single nucleotide polymorphisms (SNP) are the most frequent polymorphism in rice genome. However, SNP markers not readily employed MAS because limitations genotyping platforms. Here authors report a Golden Gate array that targets specific genes controlling yield-related traits and biotic stress resistance rice. As first step, genotypes were surveyed 31 parental varieties using Affymetrix Rice 44K...

10.1016/j.plantsci.2015.09.008 article EN cc-by Plant Science 2015-09-12

Two species of rice have been independently domesticated from different ancestral wild in Asia and Africa. Comparison mutations that underlie phenotypic physiological alterations associated with domestication traits these gives insights into the history both regions. Asian cultivated rice, Oryza sativa, African glaberrima , modified improved for common beneficial humans, including erect plant architecture, nonshattering seeds, nonpigmented pericarp, lack awns. Independent orthologous genes...

10.1073/pnas.2207105120 article EN cc-by Proceedings of the National Academy of Sciences 2023-01-17

SUMMARY Cytoplasmic male sterility (CMS) is an agronomically significant trait that causes dysfunction in pollen and anther development. It often observed during successive backcrossing between distantly related species. Here, we show Asian japonica cultivars ( Oryza sativa ) exhibit CMS when the nucleus replaced with of African rice glaberrima . The line produced stunted anthers did not set any seeds. Mitochondrial orf288 RNA was detected lines but fertility restorer lines. mitochondrial...

10.1111/tpj.17028 article EN cc-by The Plant Journal 2024-09-09

Reduced-representation sequencing (RRS) provides cost-effective and time-saving genotyping platforms. Despite the outstanding advantage of RRS in throughput, obtained genotype data usually contain a large number errors. Several error correction methods employing hidden Markov model (HMM) have been developed to overcome these issues. These assume that markers uniform rate with no bias allele read ratio. However, does occur because uneven amplification genomic fragments mismapping. In this...

10.1093/genetics/iyad055 article EN cc-by Genetics 2023-03-29

<h3>BACKGROUND</h3> Erythromycin has been reported to have an inhibitory effect on chronic inflammatory airway disease and infiltration of neutrophils into the airway. Bleomycin (BLM) often induces interstitial lung fibrosis following acute injury. A study was undertaken investigate effects erythromycin (EM) experimental bleomycin-induced injury in rats. <h3>METHODS</h3> Bleomycin-induced assessed by light microscopic examination, measurement neutrophil elastase activity interleukin 8 (IL-8)...

10.1136/thx.53.3.186 article EN Thorax 1998-03-01

Chromosome segment substitution lines (CSSLs) are rich genetic resources that can be mined for novel, agriculturally useful loci or used directly as materials breeding. To date, a number of rice CSSLs have been developed by crossing cultivars with its wild relatives means to tap into the potential alleles in improvement. Oryza nivara is relative thought progenitor O. sativa spp. indica. In present study, 26 covers entire genome contiguous, overlapping segments genomic background japonica...

10.1270/jsbbs.16131 article EN Breeding Science 2016-01-01

To counteract the growing population and climate changes, resilient varieties adapted to regional environmental changes are required. Landraces valuable genetic resources for achieving this goal. Recent ad‍vances in sequencing technology have enabled national seed/gene banks share genomic in‍formation from their collections including landraces, promoting more efficient utilization of germplasms. In study, we developed Myanmar rice First, assembled a diversity panel consisting 250 accessions...

10.1270/jsbbs.23077 article EN Breeding Science 2024-01-01

Abstract Mineral element accumulation in plants is influenced by soil conditions and varietal factors. We investigated the dynamic of 12 elements straw at flowering stage grains mature eight rice varieties with different genetic backgrounds (Japonica, Indica, admixture) times (early, middle, late) grown various pH levels. In straw, Cd, As, Mn, Zn, Ca, Mg, Cu was both factors, whereas P, Mo, K pH, Fe Ni affected grains, Cu, Ni, Mg Fe, P not altered. Only Ca showed similar trends responses K,...

10.1038/s41598-024-66036-7 article EN cc-by Scientific Reports 2024-07-02
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