A5078096004- Advanced Chemical Physics Studies
- Antimicrobial agents and applications
- Inhalation and Respiratory Drug Delivery
- Quantum, superfluid, helium dynamics
- Nanoplatforms for cancer theranostics
- Cold Atom Physics and Bose-Einstein Condensates
- Spectroscopy and Laser Applications
- Fluorine in Organic Chemistry
- Molecular Junctions and Nanostructures
- Immunotherapy and Immune Responses
- Strong Light-Matter Interactions
- Monoclonal and Polyclonal Antibodies Research
- Quantum chaos and dynamical systems
- Advanced Physical and Chemical Molecular Interactions
- RNA Interference and Gene Delivery
- Andrographolide Research and Applications
- Gut microbiota and health
- Antimicrobial Peptides and Activities
- Various Chemistry Research Topics
- Nanoparticle-Based Drug Delivery
- Peptidase Inhibition and Analysis
- Ginseng Biological Effects and Applications
Center for Life Sciences
2024
Tsinghua University
1989-2024
University of California, Riverside
1988
This study aims to assess the effects of Jidangga-7 on enhancing gut microbiota function in non-small cell lung cancer. Eighteen mice were screened and randomly divided into three groups: a control group, model group with induced cancer, treatment receiving Jidangga-7. A549 tumor cells implanted mice, formation was monitored. Upon successful induction, received via oral gavage, while other groups an equivalent volume saline. After final dose, intestinal tissues collected from each microbial...
Inducing high levels of antigen-specific CD8α
Pulmonary delivery of immunostimulatory agents such as poly(I:C) to activate double-stranded RNA sensors MDA5 and RIG-I within lung-resident antigen-presenting cells is a potential strategy enhance antitumor immunity by promoting type I interferon secretion. Nevertheless, following pulmonary delivery, suffers from rapid degradation poor endosomal escape, thus limiting its potency. Inspired the structure virus that utilizes internal viral proteins tune loading cytosolic nucleic acids, we...
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<div>Abstract<p>Pulmonary delivery of immunostimulatory agents such as poly(I:C) to activate double-stranded RNA sensors MDA5 and RIG-I within lung-resident antigen-presenting cells is a potential strategy enhance antitumor immunity by promoting type I interferon secretion. Nevertheless, following pulmonary delivery, suffers from rapid degradation poor endosomal escape, thus limiting its potency. Inspired the structure virus that utilizes internal viral proteins tune loading...
<div>Abstract<p>Pulmonary delivery of immunostimulatory agents such as poly(I:C) to activate double-stranded RNA sensors MDA5 and RIG-I within lung-resident antigen-presenting cells is a potential strategy enhance antitumor immunity by promoting type I interferon secretion. Nevertheless, following pulmonary delivery, suffers from rapid degradation poor endosomal escape, thus limiting its potency. Inspired the structure virus that utilizes internal viral proteins tune loading...
Poly I:C (pIC) can act on endosomal and cytosolic pathogen recognition receptors to enhance T cell immunity. However, the poor delivery of pIC lack facile methods for codelivery with antigens limit its efficacy. Inspired by structure a virus, we developed
Vibrational (V)–rotational (R)–translational (T) energy transfer in the inelastic scattering processes of a diatomic molecule–stationary surface system has been investigated by three different theoretical approaches. The V–T–R distribution gas–surface collision is studied quasiclassical trajectory calculations employing modified semiempirical London–Eyring–Polanyi–Sato potential. mechanism vibrational and rotational excitation projectile molecule examined. A quantum-mechanical bound state...