A5082462884- Geochemistry and Geologic Mapping
- Food composition and properties
- Wheat and Barley Genetics and Pathology
- Aquaculture disease management and microbiota
- Scientific Computing and Data Management
- Redox biology and oxidative stress
- Aquaculture Nutrition and Growth
- Free Radicals and Antioxidants
- Planetary Science and Exploration
- Protein Hydrolysis and Bioactive Peptides
- Geological Modeling and Analysis
- Data Quality and Management
- Space Exploration and Technology
- Neonatal Health and Biochemistry
- Research Data Management Practices
- Meat and Animal Product Quality
- Nitric Oxide and Endothelin Effects
- Celiac Disease Research and Management
- Food Quality and Safety Studies
- Biochemical effects in animals
- Vascular Malformations and Hemangiomas
- BRCA gene mutations in cancer
- Electron Spin Resonance Studies
- Biomedical Research and Pathophysiology
- Heme Oxygenase-1 and Carbon Monoxide
Complejo Hospitalario Universitario de Santiago
2025
Complexo Hospitalario Universitario A Coruña
2025
Pontificia Universidad Católica de Chile
2019-2025
University of Ottawa
2021-2025
Lamont-Doherty Earth Observatory
2020-2023
Columbia University
2020-2023
Medical College of Wisconsin
2022
American Geophysical Union
2022
Polytechnic University of Puerto Rico
2017
Hospital Pablo Tobon Uribe
2012-2014
Approximately 5% of all breast cancers can be attributed to a mutation in the BRCA1 or BRCA2 gene. The genetic component cancer Colombia has been, for most part, studied on cases from Bogota region. Five different founder mutations were two studies patients It is important that frequency established among unselected other regions order estimate burden this and plan services. aim study was establish frequencies BRCA genes family history age, Medellin, Colombia.We enrolled 280 women with large...
The pentose phosphate pathway (PPP) is a key metabolic pathway. oxidative phase of this process involves three reactions catalyzed by glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconolactonase (6PGL) and 6-phosphogluconate (6PGDH) enzymes. first third steps (catalyzed G6PDH 6PGDH, respectively) are responsible for generating reduced nicotinamide adenine dinucleotide (NAPDH), cofactor maintaining the reducing power cells detoxification both endogenous exogenous oxidants...
Ultrashort peptides hold immense potential as structural tools for enhancing the colloidal stability of nanomaterials, such nanogold. However, applications have been largely unexplored in part due to inherent complexity designing, synthesizing, and testing short nanoparticle stabilizers. In this work, we use a motif-function-guided process peptide synthesis high throughput screening evaluate spherical nanogold solutions pentapeptides. We successfully built library capable stabilizing at...
ABSTRACT High and low molecular weight glutenin subunits (HMW‐GS LMW‐GS, respectively) are the main factors determining viscoelastic properties of wheat dough. The mechanical 29 samples kernels differing in HMW‐GS were evaluated with load‐compression tests. Samples grouped by genotypes composition (allelic variants: Glu‐A1 : null, 1, 2*; Glu‐B1 7, 7+8, 7+9, 13+16, 17+18; Glu‐D1 5+10, 2+12). Groups representing 1 7+9 5+10 generally possessed hard grain showed largest kernel elasticity values,...
ABSTRACT The mechanical and viscoelastic properties of intact wheat kernels 36 cultivars differing in low molecular weight glutenin subunit (LMW‐GS) composition (loci Glu‐A3, Glu‐B3 , Glu‐D3 ) were evaluated using load‐compression tests. Comparison among genotypic groups representing Glu‐3 allelic variants showed that the alleles Glu‐A3 b, c, d; d, g, h; a, had harder kernel texture, higher elastic work larger gluten strength‐related parameters than those possessing e; f, i j (translocation...
Dityrosine and ditryptophan bonds have been implied in protein crosslinking. This is associated with oxidative stress conditions including those involved neurodegenerative pathologies age-related processes. Formation of dityrosine derives from radical-radical reactions involving Tyr˙ Trp˙ radicals. However, cross leading to Tyr-Trp crosslinks their biological consequences less explored. In the present work we hypothesized that exposure free Tyr Trp a high concentration carbonate anion...
Civilian extremity trauma with vascular injury carries a significant risk of morbidity, limb loss, and mortality. We aim to describe the trends in repair compare outcomes between surgeons.We performed single-center retrospective review patients 18 years or older requiring surgical intervention January 2009 December 2019. Demographics, characteristics, operative course, hospital course were analyzed. Descriptive statistics used examine management trends, compared for arterial repairs....
Abstract Escherichia coli glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate (6PGDH) are key enzymes of the pentose phosphate pathway, responsible for NADPH production in cells. We investigated modification both mediated by peroxyl radicals (ROO · ) to determine their respective susceptibilities mechanisms oxidation. G6PDH 6PGDH were incubated with AAPH (2,2′-azobis(2-methylpropionamidine)dihydrochloride), which was employed as ROO source. The enzymatic activities determined...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in death of millions. also a shortage personal protective equipment (PPE) many regions around world, particularly middle- low-income countries. shortages PPE, such as N95 respirators, is something that will persist until an effective vaccine made available. Thus, devices while being easy to operate can be rapidly deployed...
The ORAC (Oxygen Radical Absorbance Capacity) assay is commonly employed for determining the antioxidant capacity of bioactive peptides. To gain insights into meaning this index peptides containing a single Trp, we studied consumption residue and fluorescein (FLH, probe method), induced by radicals generated AAPH (2,2′-Azo-bis(2-amidinopropane) dihydrochloride) thermolysis. values were rationalized from kinetics computational calculations bond dissociation energies (BDE) N-H (indole ring...
Summary A puffed product was made by extruding corn flour supplemented with soybean and safflower pastes. Mixes the following proportions of flour, pastes: (i) 89:8:3, (ii) 83:11:6 (iii) 80:17:3 were extruded. The pastes used had 6.6%, 45.9% 32.9% protein content respectively. In addition, paste contained 11.78 units inhibited trypsin/mg sample, which means it appropriate for human consumption. Sensory evaluation extruded products showed that there no significant differences in flavour,...
The functional properties of globin protein obtained from decolorisation red cells bovine blood were studied over a pH range 2 to 12. Maximum foam stability and capacity observed at 10 buffer 11. In the 6–8, showed an intermediate solubility (76–80%) while emulsifying activity, increased with increasing pH. excellent foaming emulsification characteristics make acceptable alternative as emulsifier agent in food products. © 1999 Society Chemical Industry
Malting quality of feed and malting barley treated by microwave irradiation for 0, 4, 5, 8, 10, 15, 20, 25 sec was evaluated. Microwave periods longer than 10 increased kernel temperature higher the physiological limit significantly affected germination. With 4 irradiation, hardness decreased transformed into malt good quality. The Adabella without treatment showed double (49.3 N) Pastor Ortiz almost three times (59.8 Esmeralda (23.7 N). 8 increased. Irradiation barleys extract content in...