- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Mosquito-borne diseases and control
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Insects and Parasite Interactions
- Malaria Research and Control
- Respiratory and Cough-Related Research
- Eosinophilic Disorders and Syndromes
- Mast cells and histamine
- Quality and Safety in Healthcare
- Cancer Genomics and Diagnostics
- Animal and Plant Science Education
- COVID-19 epidemiological studies
- HER2/EGFR in Cancer Research
- Blood groups and transfusion
- Inhalation and Respiratory Drug Delivery
- Psychology of Moral and Emotional Judgment
- Pharmaceutical industry and healthcare
- Nutrition, Genetics, and Disease
- Public Health and Environmental Issues
- BRCA gene mutations in cancer
- Biomedical and Engineering Education
- Contact Dermatitis and Allergies
Fundación Santa Fe de Bogotá
2024
Universidad de Antioquia
2009-2019
Integral Consulting (United States)
2018
Fundación Con Vida
2017
Universidad del Valle
2009
Approximately 5% of all breast cancers can be attributed to a mutation in the BRCA1 or BRCA2 gene. The genetic component cancer Colombia has been, for most part, studied on cases from Bogota region. Five different founder mutations were two studies patients It is important that frequency established among unselected other regions order estimate burden this and plan services. aim study was establish frequencies BRCA genes family history age, Medellin, Colombia.We enrolled 280 women with large...
Despite much research in the identification of areas with malaria, it is urgent to further investigate mapping techniques achieve better approaches strategies prevent, mitigate, and eradicate mosquito illness eventually. By using spatial distributed modeling Geographical Information Systems (GIS), study proposes methodology map malaria risk zoning for municipality Buenaventura Colombia. The model proposed by Craig et al.¹ climatic information was adapted conditions area regarding scale...
Anaphylaxis is defined as a systemic, rapid onset, and potentially fatal hypersensitivity reaction, with variable clinical manifestations severity resulting from the sudden release of mast cell basophil mediators. The diagnosis this entity fundamentally clinical, based on patterns manifestation exposure to possible trigger. Currently several studies indicate deficiencies in identification management disease, which generates an increase mortality. In review we present practical points...
Abstract Background The allergic phenotype is responsible for more than 50% of severe asthma cases. In a stepwise approach, add-on treatments such as anti-IgE are used (SAA). This study was aimed to describe the real-world effectiveness omalizumab in adult and pediatric patients with SAA Colombia. Methods an observational, non-interventional, retrospective study. Data from that received at least one month treatment obtained medical records eight sites Time-zero (t − 0) defined date...
In Latin America there are few data about the factors that influence control and severity of asthma.To describe association between IgE sensitization to intra-home allergens housing conditions in asthma.Sensitization aero-allergens was evaluated by skin prick test socio-demographic a questionnaire population 6 14 years age with diagnosis asthma. Asthma measured according spirometric results application ACT (Asthma Control Test); symptom GINA guideline.A total 150 resident patients from...
Background: Dupilumab is a treatment approved for uncontrolled moderate-to-severe atopic dermatitis (AD).Tropical and developing countries such as Colombia have characteristics that may impact the natural history of AD access to medical treatments.In sense, we aimed describe effectiveness safety dupilumab in adults with moderate severe Colombian multicenter cohort.Methods: Multicenter descriptive study included patients who started between March 2018 May 2020 6 centers.Disease severity was...
Antecedentes: Varios reportes evidencian la necesidad de mayor conocimiento los médicos acerca criterios diagnósticos y manejo anafilaxia, condición que puede tener consecuencias fatales.Objetivo: Evaluar en Colombia conocimientos no alergólogos, aspectos fundamentales anafilaxia el diagnóstico oportuno tratamiento.Métodos: Estudio transversal realizado mediante una encuesta 11 preguntas relativas a clínicos dirigida generales especialistas residentes Colombia. El análisis resultados se hizo...
Introducción y objetivos. La hemofilia A adquirida es un trastorno de la coagulación caracterizado por una alteración en los niveles del factor VIII secundaria a producción autoanticuerpos neutralizantes está asociada enfermedades autoinmunes. Nuestro objetivo presentar el caso clínico paciente con antecedente hepatitis autoinmune lupus eritematoso sistémico, quien desarrolló adquirida. Describimos su evolución, respuesta terapéutica aportamos revisión actualizada sobre tema.
Introducción y objetivos. El cáncer de mama HER2 positivo es el principal factor riesgo para desarrollar metástasis cerebrales. Estas son un reto terapéutico por la alta morbilidad corta supervivencia asociada. La piedra angular del tratamiento control local, seguido terapia sistémica anti-HER2. Reportamos caso una paciente con
.
.
Objetivo: evaluar los cambios en la tasa anual de sangrados (TAS) y el comportamiento del título inhibidores una serie casos pacientes pediátricos con hemofilia A severa e alta respuesta, quienes recibieron profilaxis agentes bypass posteriormente fueron cambiados a Emicizumab. Materiales Métodos: estudio retrospectivo observacional crossover (antes después) que evaluó TAS cohorte recibió durante 52 semanas y, posteriormente, esos mismos Se revisaron forma retrospectiva las historias...