Nelson J. Alvis-Zakzuk
- Global Public Health Policies and Epidemiology
- Healthcare Systems and Reforms
- Global Maternal and Child Health
- Rheumatoid Arthritis Research and Therapies
- Child Nutrition and Water Access
- Chronic Disease Management Strategies
- Public Health and Environmental Issues
- COVID-19 Clinical Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Health and Lifestyle Studies
- Autoimmune and Inflammatory Disorders Research
- Climate Change and Health Impacts
- Biosimilars and Bioanalytical Methods
- Respiratory viral infections research
- Food Security and Health in Diverse Populations
- Public Health and Social Inequalities
- Healthcare Policy and Management
- Pneumonia and Respiratory Infections
- Vaccine Coverage and Hesitancy
- Spondyloarthritis Studies and Treatments
- Influenza Virus Research Studies
- Dermatology and Skin Diseases
- Hepatitis C virus research
- Air Quality and Health Impacts
Universidade de São Paulo
2022-2025
University of the Coast
2018-2025
World Health Organization Regional Office for the Americas
2025
Instituto de Saúde
2023-2024
Institute for Health Metrics and Evaluation
2020-2024
University of Washington
2020-2024
Weatherford College
2024
World Health Organization
2024
Royal North Shore Hospital
2023
The University of Sydney
2023
<h2>Summary</h2><h3>Background</h3> In an era of shifting global agendas and expanded emphasis on non-communicable diseases injuries along with communicable diseases, sound evidence trends by cause at the national level is essential. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) provides a systematic scientific assessment published, publicly available, contributed data incidence, prevalence, mortality for mutually exclusive collectively exhaustive list injuries....
Detailed, comprehensive, and timely reporting on population health by underlying causes of disability premature death is crucial to understanding responding complex patterns disease injury burden over time across age groups, sexes, locations. The availability estimates can promote evidence-based interventions that enable public researchers, policy makers, other professionals implement strategies mitigate diseases. It also facilitate more rigorous monitoring progress towards national...
BackgroundAchieving universal health coverage (UHC) involves all people receiving the services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority for both countries and global institutions, as highlighted by agenda UN Sustainable Development Goals (SDGs) WHO's Thirteenth General Programme Work (GPW13). Measuring effective at health-system level important understanding whether are aligned with countries' profiles sufficient...
BackgroundSustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction neonatal death to less than 12 per 1000 livebirths, and children younger 5 years 25 for each country by 2030. To understand current rates, recent trends, potential trajectories mortality the next decade, we present Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019 findings all-cause cause-specific in age, with multiple scenarios 2030 that include consideration effects...
<h2>Summary</h2><h3>Background</h3> The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these is issue of financing national especially low-income middle-income countries (LMICs), as well a robust global system for preparedness. We aimed provide comparative assessment spending at onset pandemic; characterise amount development assistance preparedness response disbursed first 2 years...
The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years adults has not been studied as comprehensively it younger years. We assessed the trends LRIs across all age groups by sex, for 204 countries territories.
<h2>Summary</h2><h3>Background</h3> Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease improving wellbeing. Comprehensive, high-resolution estimates are important inform progress towards achieving this goal. We aimed produce geospatial of facilities. <h3>Methods</h3> used a Bayesian geostatistical model data from 600 sources across more than 88 low-income...
High prevalence of diabetes has been reported in the Americas, but no comprehensive analysis burden and related factors for region is available. We aimed to describe type 1 2 that hyperglycaemia Americas from 1990 2019.We used estimates GBD 2019 evaluate adults aged 20 years or older high fasting plasma glucose 25 39 countries territories six regions 2019. The main source estimate mortality attributable chronic kidney disease due was vital registration. Mortality overall (ie, disease)...
The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific rarely studied. study aims to investigate pattern trend 1990 2019.We collected detailed information on six major IMIDs, including asthma, bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, atopic dermatitis, between 2019, derived Global Burden Disease in 2019. average annual percent change (AAPC) number incidents age standardized rate (ASR) by sex, age,...
<h2>Summary</h2><h3>Background</h3> Global evaluations of the progress towards WHO End TB Strategy 2020 interim milestones on mortality (35% reduction) and incidence (20% have not been age specific. We aimed to assess global, regional, national-level burdens trends in tuberculosis its risk factors across five separate groups, from 1990 2021, report age-specific between 2015 2020. <h3>Methods</h3> used Burden Diseases, Injuries, Risk Factors Study 2021 (GBD 2021) analytical framework compute...
Across low-income and middle-income countries (LMICs), one in ten deaths children younger than 5 years is attributable to diarrhoea. The substantial between-country variation both diarrhoea incidence mortality interventions that protect children, prevent infection, treat disease. Identifying subnational regions with the highest burden mapping associated risk factors can aid reducing preventable childhood
Abstract A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates overweight wasting prevalence among children under 5 years age in 105 low- middle-income countries (LMICs) from 2000 to 2017 aggregate these policy-relevant administrative units. Wasting decreased overall across LMICs between 2017, 8.4% (62.3 (55.1–70.8) million) 6.4% (58.3 (47.6–70.7) million), but is predicted...
Globally, transport and unintentional injuries persist as leading preventable causes of mortality morbidity for adolescents. We sought to report comprehensive trends in injury-related adolescents aged 10-24 years during the past three decades.Using Global Burden Disease, Injuries, Risk Factors 2019 Study, we analysed disability-adjusted life-years (DALYs) attributed 204 countries. is reported absolute numbers age-standardised rates per 100 000 population by sex, age group (10-14, 15-19,...
<h2>Summary</h2><h3>Background</h3> This study aims to estimate the burden, trends, forecasts, and disparities of early musculoskeletal (MSK) disorders among individuals ages 15 39 years. <h3>Methods</h3> The global prevalence, years lived with disabilities (YLDs), disability-adjusted life (DALYs), projection, inequality were estimated for MSK diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck (NP), gout, other diseases (OMSKDs). <h3>Findings</h3>...
The six global nutrition targets (GNTs) related to low birthweight, exclusive breastfeeding, child growth (ie, wasting, stunting, and overweight), anaemia among females of reproductive age were chosen by the World Health Assembly in 2012 as key indicators maternal health, but there has yet be a comprehensive report on progress for period 2021. We aimed evaluate levels, trends, observed-to-expected prevalence attributable burden from 2021, with projections 2050, 204 countries territories.
BackgroundColombia detected its first coronavirus disease 2019 (COVID-19) case on March 2, 2020. From 22 to April 25, it implemented a national lockdown that, apparently, allowed the country keep low incidence and mortality rate up mid-May. Forced by economic losses, government then opened many commercial activities, which was followed an increase in cases deaths. This paper presents critical analysis of Colombian surveillance data order identify strengths pitfalls control measures.MethodsA...
BackgroundOral rehydration solution (ORS) is a form of oral therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according UNICEF estimates, less than half children younger 5 years with in low-income and middle-income countries (LMICs) received ORS 2016. A variety recommended home fluids (RHF) exist as alternative forms ORT; however, it unclear whether RHF prevent mortality. Previous studies have shown considerable variation between use, but...
To estimate the baseline to measure one of three indicators World Health Organization (WHO) End TB strategy (2015-2035), costs incurred by patients affected tuberculosis (TB) during a treatment episode and proportion households facing catastrophic (CC) associated risk factors, in Colombia, 2021.
In February 2021, Colombia began mass vaccination against COVID-19 using mainly BNT162b2 and CoronaVac vaccines. We aimed to estimate vaccine effectiveness (VE) prevent symptomatic cases, hospitalization, critical care admission, deaths in a cohort of 796,072 insured subjects older than 40 years northern Colombia, setting with high SARS-CoV-2 transmission. identified individuals vaccinated between March 1st 2021 August 15th 2021. included hospitalizations, admissions, patients confirmed as...