Gianfranco Alicandro
- Cystic Fibrosis Research Advances
- Health disparities and outcomes
- Global Health Care Issues
- Climate Change and Health Impacts
- COVID-19 and healthcare impacts
- Neonatal Respiratory Health Research
- Nutritional Studies and Diet
- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- Employment and Welfare Studies
- COVID-19 Clinical Research Studies
- Child Nutrition and Feeding Issues
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Helicobacter pylori-related gastroenterology studies
- Childhood Cancer Survivors' Quality of Life
- Cancer Risks and Factors
- Global Maternal and Child Health
- Suicide and Self-Harm Studies
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare cost, quality, practices
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2011-2025
University of Milan
2015-2024
Institute for Health Metrics and Evaluation
2020-2024
University of Washington
2020-2024
Istituto Nazionale di Statistica
2014-2023
University of Bologna
2023
Tumori Foundation
2023
University of Lausanne
2023
Cystic Fibrosis Foundation
2022
University College London
2021
<h2>Summary</h2><h3>Background</h3> In an era of shifting global agendas and expanded emphasis on non-communicable diseases injuries along with communicable diseases, sound evidence trends by cause at the national level is essential. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) provides a systematic scientific assessment published, publicly available, contributed data incidence, prevalence, mortality for mutually exclusive collectively exhaustive list injuries....
<h2>Summary</h2><h3>Background</h3> Rigorous analysis of levels and trends in exposure to leading risk factors quantification their effect on human health are important identify where public is making progress which cases current efforts inadequate. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019 provides a standardised comprehensive assessment the magnitude factor exposure, relative risk, attributable burden disease. <h3>Methods</h3> GBD estimated mortality, years life...
<h2>Summary</h2><h3>Background</h3> Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range social, economic, public health issues that affect populations worldwide. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019 produced updated comprehensive assessments the key indicators fertility, mortality, migration, population 204 countries territories selected subnational locations from 1950 to 2019. <h3>Methods</h3> 8078 country-years...
Abstract Objective To estimate the direct and indirect effects of covid-19 pandemic on mortality in 2020 29 high income countries with reliable complete age sex disaggregated data. Design Time series study countries. Setting Austria, Belgium, Czech Republic, Denmark, England Wales, Estonia, Finland, France, Germany, Greece, Hungary, Israel, Italy, Latvia, Lithuania, Netherlands, New Zealand, Northern Ireland, Norway, Poland, Portugal, Scotland, Slovakia, Slovenia, South Korea, Spain, Sweden,...
BackgroundSustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction neonatal death to less than 12 per 1000 livebirths, and children younger 5 years 25 for each country by 2030. To understand current rates, recent trends, potential trajectories mortality the next decade, we present Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019 findings all-cause cause-specific in age, with multiple scenarios 2030 that include consideration effects...
Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease with great impact on healthcare systems worldwide. As targeted therapies have transformed the therapeutic landscape, updated estimates of Global Burden Disease (GBD) imposed by psoriasis are necessary in order to evaluate effects past health care policies and orient inform new national international strategies. Methods: Data were extracted from GBD 2019 study, which collates systematic review relevant...
Documentation of patterns and long-term trends in mortality young people, which reflect huge changes demographic social determinants adolescent health, enables identification global investment priorities for this age group. We aimed to analyse data on the number deaths, years life lost, rates by sex group people aged 10-24 204 countries territories from 1950 2019 use estimates Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019.
Decades of steady improvements in life expectancy Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes risk factors and cause-specific death rates different European countries related those during pandemic. used data methods Global Burden Diseases, Injuries, Risk Factors Study 2021 compare at birth, causes death, population exposure 16 Economic Area (Austria, Belgium, Denmark, Finland, France, Germany,...
In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup unique epidemiology, clinical care needs, societal impact. Comprehensive estimates in (aged 15-39 years) lacking. To address this gap, we analysed results from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019, focus on outcome disability-adjusted life-years (DALYs), to inform control measures adults.
Objectives: We aimed at describing the attitudes towards influenza vaccination and a potential COVID-19 vaccine in Italy. Methods: A nationally representative survey based on 1055 Italians aged 15-85 years was conducted September 16-28, 2020. Results: found that 40.8% of population reported intention to be vaccinated against next winter 53.7% would accept receive vaccine. The percentages were higher among individuals 55 over (58.8% for 58.2% vaccine) professionals, managers teachers as...
The impact of COVID-19 on mortality from specific causes death remains poorly understood. This study analysed cause-of-death data provided by the World Health Organization 2011 to 2019 estimate excess deaths in 2020 30 countries. Over-dispersed Poisson regression models were used number that would have been expected if pandemic had not occurred, separately for men and women. included year age categories account temporal trends changes size structure populations. Excess calculated subtracting...
Abstract Background Elexacaftor‐tezacaftor‐ivacaftor (ETI) is a highly effective cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulating therapy for people with CF and at least one F508del variant. However, there limited data about the safety efficacy of this in pediatric populations real‐world settings. This study aimed evaluating effectiveness, tolerability, ETI children CF. Methods was prospective observational including all aged 6–11 years who initiated between October...
Over the past two decades, Italian National Health Service has been gradually decentralised, with Italy's 21 regional governments now responsible for managing their health services. This change, coupled austerity measures and a steadily ageing population, adversely affected universal coverage equity, exacerbating inequalities disparities. study aimed to analyse time trends subnational differences in burden of disease from 2000 2019, 2019 2021 capture effects COVID-19 pandemic. uses estimates...