A5020059089- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Glutathione Transferases and Polymorphisms
- Heart Failure Treatment and Management
- Insect and Pesticide Research
- Cardiovascular Function and Risk Factors
- COVID-19 Pandemic Impacts
- IL-33, ST2, and ILC Pathways
- Clinical Nutrition and Gastroenterology
- Renal cell carcinoma treatment
- Intestinal Malrotation and Obstruction Disorders
- COVID-19 epidemiological studies
- Business, Innovation, and Economy
- Eosinophilic Esophagitis
- Parasites and Host Interactions
- COVID-19 and healthcare impacts
- Immune responses and vaccinations
- Orthopaedic implants and arthroplasty
- Educational and Organizational Development
- Public Health and Environmental Issues
- Entomological Studies and Ecology
- Agricultural safety and regulations
- Healthcare Systems and Reforms
- Gastroesophageal reflux and treatments
- Inflammatory Bowel Disease
Hospital Sant Joan de Déu Barcelona
2023-2024
University of Cartagena
2016-2024
Henry Ford Macomb Hospital
2022
Henry Ford Health System
2020
Abstract Background Recent trials suggested that the Crohn’s disease (CD) exclusion diet (CDED) plus partial enteral nutrition (PEN) is a safe and effective strategy in remission induction of paediatric-onset CD. However, real-world evidence regarding safety efficacy CDED PEN approach still lacking. The present case-series study reported our experience with outcomes CD at onset after loss response to biologics. Methods We conducted retrospective chart review on children who were treated...
Background Ascaris lumbricoides cystatin (Al-CPI) prevents the development of allergic airway inflammation and dextran-induced colitis in mice models. It has been suggested that helminth-derived cystatins inhibit cathepsins dendritic cells (DC), but their immunomodulatory mechanisms are unclear. We aimed to analyze transcriptional profile human monocyte-derived DC (moDC) upon stimulation with Al-CPI elucidate target genes pathways parasite immunomodulation. Methods moDC were generated from...
To compare the relative frequencies of immune cell populations in peripheral blood according to
Papular urticaria (PU) is a common insect bite skin hypersensitivity in tropical countries. In order to gain insight into its causal allergens, we aimed evaluate cellular and humoral immune responses the recombinant salivary antigen Cte f 2 from cat flea Ctenocephalides felis.Sixty patients with PU 27 healthy controls were included this study. Specific IgE, IgG, IgG1, IgG4 against C. felis extract determined by ELISA. The T-cell response was analyzed using carboxyfluorescein succinimidyl...
infection is one of the most common soil-transmitted helminthiasis and IgE response to this helminth may increase risk asthma, bronchial hyperreactivity atopy. There not enough evidence showing role group-2 innate lymphoid cells (ILC2) in pathogenesis infections humans. Here, we aimed investigate characterize influence
To estimate the economic burden associated with COVID-19 in Córdoba, Colombia, 2020 and 2021.
Resumo Objetivo: Estimar a carga econômica associada à covid-19 em Córdoba, Colômbia, entre 2020 e 2021. Métodos: Estudo de avaliação da covid-19. Os custos diretos foram analisados segundo terceiros pagadores, usando-se bases dados administrativas entrevistas. A agregação dos foi realizada o método bottom-up. indiretos estimados pela perda produtividade. Testes contraste ortogonais modelos regressão estatísticos com 5% significância. Resultados: Foram estudadas 1.800 pessoas O custo...
Background: Dupilumab is a treatment approved for uncontrolled moderate-to-severe atopic dermatitis (AD).Tropical and developing countries such as Colombia have characteristics that may impact the natural history of AD access to medical treatments.In sense, we aimed describe effectiveness safety dupilumab in adults with moderate severe Colombian multicenter cohort.Methods: Multicenter descriptive study included patients who started between March 2018 May 2020 6 centers.Disease severity was...
There are different sources of allergenic glutathione transferase proteins (GST), including house dust mites and helminths. In the genus Ascaris, it is expected that GST family comprises at least 6 isoforms; but only information about properties a sigma-like available. However, pi-class isoform was also identified in purified native fraction from displaying differential IgE reactivity among tested patients (Acevedo et al, PloS one. 2013;8(11):e78353). Here, we characterize activity...