- Intestinal Malrotation and Obstruction Disorders
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Immunodeficiency and Autoimmune Disorders
- Bacterial biofilms and quorum sensing
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Gastrointestinal disorders and treatments
- Chemokine receptors and signaling
- Cell Adhesion Molecules Research
- Organ Transplantation Techniques and Outcomes
- Prostate Cancer Treatment and Research
- Autoimmune Bullous Skin Diseases
- Genetic Syndromes and Imprinting
- Respiratory Support and Mechanisms
- Organ Donation and Transplantation
- Bacterial Identification and Susceptibility Testing
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Infant Development and Preterm Care
- Pediatric health and respiratory diseases
- Congenital Diaphragmatic Hernia Studies
- Palliative Care and End-of-Life Issues
- Autoimmune and Inflammatory Disorders Research
- Congenital gastrointestinal and neural anomalies
- Acne and Rosacea Treatments and Effects
Universidad Nacional de Colombia
2017-2024
Fundación Neumológica Colombiana
2023-2024
University of Washington
2023
Seattle University
2023
National Center for Genetic Engineering and Biotechnology
2023
Rafael Advanced Defense Systems (Israel)
2023
Hospital San Juan de Dios
2023
Hospital Nacional de Niños
2023
University of Cartagena
2012-2021
New York Medical College
2018
Abstract Background The CDC and ACIP recommend COVID-19 vaccination for patients with inborn errors of immunity (IEI). Not much is known about vaccine safety in IEI, whether attenuates infection severity IEI. Objective To estimate examine effect on outcomes Methods We built a secure registry database conjunction the US Immunodeficiency Network to frequency indicators effectiveness IEI patients. opened January 1, 2022, closed August 19, 2022. Results Physicians entered data 1245 from 24...
Atypical chemokine receptors have recently emerged as important molecular players in health and diseases; they affect availability function impact a multitude of pathophysiological events, including the tumorigenesis process. This family atypical comprises five members: ACKR1/DARC, ACKR2/D6, ACKR3/CXCR7, ACKR4/CCRL1, ACKR5/CCRL2. work evaluated differential expression these prostate cancer using quantitative PCR. Further evaluation CCRL2 at protein level confirmed its overexpression...
Introduction: The host niche for Staphylococcus aureus (SA) are the anterior nares; however, vaginal colonization rates between 14% and 17.1% in pregnant women have been recently reported, raising interest about potential risk postpartum neonates from colonized mothers.Objectives: To determine prevalence of nasal SA antibiotic susceptibility isolates attending a maternity hospital Cartagena, Colombia.Methods: Nasal swabs were obtained participants subjected to microbiological molecular...
Introducción: la colitis ulcerativa pediátrica (CUP), enfermedad de Crohn (ECP) y inflamatoria intestinal no clasificable (EIIPNC) tienen particularidades clínicas psicosociales que las diferencian del adulto pueden condicionar enfoques terapéuticos distintos por posibles repercusiones nutricionales, crecimiento desarrollo, lo representa un desafío para el pediatra gastroenterólogo. Objetivo: desarrollar recomendaciones basadas en evidencia consenso expertos diagnóstico tratamiento oportunos...
Although infrequent, bowel interposition between diaphragm and liver, Chilaiditi's sign or syndrome (without with gastrointestinal symptoms), are a major clinical condition given the possibilities of differential diagnosis, such as pneumoperitoneum, diaphragmatic hernia subphrenic abscess.Objective: To report cases two preschool patients Chilaiditi´s syndrome, well to highlight importance this condition.Clinical cases: Case 1: A male preschooler evaluated by respiratory disease without...
Objective: Despite advancements, hypertension and its associated factors remain the leading cause of global death with concerning increases. This study aimed to estimate whether impact mass education in adults subsequently adolescents children Tunja, Boyacá, Colombia S.A influenced their knowledge these factors. Methods: Cross-sectional prospective community individuals > 18 years, open invitation various points care collecting information Framingham surveys, blood pressure measurement,...
Gestational pemphigoid is a rare autoimmune skin condition specific to pregnancy and the postpartum period, with variable course. There are currently no standardized guidelines referring evidence-based therapeutic strategies. Intravenous immunoglobulin (IVIG) has recently emerged as safe effective steroid-sparing option second-line treatment for cases refractory conventional steroid therapy managing relapses. We present case of 36-year-old primigravida patient diagnosed gestational who...
Autoimmune lymphoproliferative syndrome (ALPS) is a primary immune regulatory disorder (PIRD). This disease usually develops during childhood. However, atypically, some cases may have their onset in adulthood. We report the case of 44-year-old woman with history autoimmune hemolytic anemia at 33 years old. The patient presented due to asthenia and large, painful lymph node left axillary region for last four months. Enlargement inguinal nodes was found by mammography, breast, abdominal...
This study aimed to correlate the genetic profile of NUDT15 and TPMT genes with side effects treatment pediatric patients acute lymphoid leukemia who were undergoing maintenance therapy at a tertiary care hospital in 2017.This was an analytical, longitudinal, observational which genotypes interest determined by PCR allelic discrimination TaqMan® probes receiving chemotherapy during phase Pediatric Hematology Oncology Unit 2017. Sociodemographic clinical data corresponding first six months...
Emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains in healthcare settings has changed the hospital epidemiology MRSA last few years. Despite a global increase frequency, infections caused by methicillin-susceptible S. (MSSA) have persisted and community. isolates were collected between 2009 2017 at Children's Hospital Caribbean city South America. Methicillin-resistant subjected to SCCmec typing. Representative analyzed multilocus sequence typing...
El estudio del nódulo pulmonar en pediatría es un desafío diagnóstico, se debe tener cuenta diferentes patologías, especialmente infecciones. En países desarrollo, donde la infección por tuberculosis endémica, uno de los diagnósticos más probables; sin embargo, las neoplasias como posibilidad diagnóstica no deben desestimarse.Objetivo: Describir el caso clínico una paciente con quien después descartar causas frecuentes diagnosticó malignidad primaria.Caso Clínico: Adolescente 17 años,...
Abstract Background: Prostate cancer progression is a complex process in which chemokines and their receptors play an important role related to tumor survival, growth, metastasis. Objectives: 1) To determine the expression profiles of proinflammatory prostate cell line supernatants association with metastatic phenotype, 2) whether these are present exosomes released from lines examined. Methods: investigated included PWR-1E (non-tumorigenic), LNCaP (low potential) PC-3 (high potential). The...
<b>Background:</b> Early onset of asthma has been associated with an allergic phenotype whereas late the eosinophilic phenotype. Our aim was to describe distribution phenotypes according symptoms in adult patients evaluated at interdisciplinary Severe Asthma Board Fundación Neumológica Colombiana Bogota. <b>Methods:</b> Cross-sectional study that included all severe board since 2019. Early-onset initiation asthmatic 12 years age or younger and late-onset after age. Phenotypes were defined as...