A5082561909- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Colorectal Cancer Screening and Detection
- Advanced Neural Network Applications
- Medical Image Segmentation Techniques
- Ophthalmology and Visual Impairment Studies
- Cancer Research and Treatments
- Medical Imaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Cancer, Hypoxia, and Metabolism
- Immune Cell Function and Interaction
- Photoacoustic and Ultrasonic Imaging
- Medical Imaging and Analysis
- Advanced Sensor and Energy Harvesting Materials
- Glycosylation and Glycoproteins Research
- CCD and CMOS Imaging Sensors
- Tissue Engineering and Regenerative Medicine
- Cancer-related Molecular Pathways
- Polydiacetylene-based materials and applications
- COVID-19 diagnosis using AI
- Viral Infections and Vectors
- Integrated Circuits and Semiconductor Failure Analysis
Dongguk University
2023-2025
University of the Philippines Los Baños
2023
National University of Singapore
2023
Seoul National University Hospital
2019-2022
Seoul National University
2019-2021
Yonsei University
2020
Triple-negative breast cancer (TNBC) presents treatment challenges due to a lack of detectable surface receptors. Natural killer (NK) cell-based adaptive immunotherapy is promising because the characteristic anticancer effects killing malignant cells directly by secreting cytokines and lytic granules. To maximize recognition ability NK cells, biomaterial-mediated ex vivo cell engineering has been developed for sufficient membrane immobilization tumor-targeting ligands via hydrophobic...
Abstract Natural killer (NK) cells have clinical advantages in adoptive cell therapy owing to their inherent anticancer efficacy and ability identify eliminate malignant tumors. However, insufficient cancer-targeting ligands on NK surfaces often inhibit immunotherapeutic performance, especially immunosuppressive tumor microenvironment. To facilitate recognition subsequent function of cells, we developed hyaluronic acid (HA, target CD44 overexpressed onto cancer cells)-poly(ethylene glycol)...
Despite recent innovations and advances in early diagnosis, the prognosis of advanced gastric cancer remains poor due to a limited number available therapeutics. Here, we employed pharmacogenomic analysis 37 cell lines 1345 small-molecule pharmacological compounds investigate biomarkers predictive cytotoxicity among cells tested drugs. We discovered that expression CCNA2, encoding cyclin A2, was commonly associated with responses polo-like kinase 1 (PLK1) inhibitors (BI-2536 volasertib)....
Mucin 1 (MUC1) is a transmembrane glycoprotein involved in tumorigenesis of diverse cancers. However, the role MUC1 glioblastoma (GBM) has not yet been fully explored. In this study, anticancer mechanism suppression GBM was investigated. The expression level analyzed human glioma and paired normal brain tissues. overexpressed negatively associated with overall survival. Moreover, we silenced to investigate its effect cell lines found that knockdown inhibited proliferation resulted cycle...
Ischemic vascular diseases remain leading causes of disability and death. Although various clinical therapies have been tried, reperfusion injury is a major issue, occurring when blood recirculates at the damaged lesion. As an alternative approach, cell-based therapy has emerged. Mesenchymal stem cells (MSCs) are attractive cellular candidates due to their therapeutic capacities, including differentiation, safety, angiogenesis, tissue repair. However, low levels receptors/ligands limit...
Purpose: To investigate the long-term effects of wearing orthokeratology (OK) lenses for more than 5 years on progression myopia and elongation axial length in children.Methods: The study included patients aged 6-12 with ranging from -0.5 D to -5.0 astigmatism ≤ 2.0 who had worn ≥ years. A retrospective analysis was conducted comparing a control group similar demographics wore glasses. Spherical equivalent (SE) changes were compared between 28 subjects (56 eyes) OK lens 37 (74 group....
Abstract Numerous studies reported a usefulness of 5-ALA fluorescence-guided surgery (FGS) in high grade gliomas. However, fluorescence pattern and intensity is variable among In this study, we report our extensive experiences FGS various gliomas focusing on epidemiological data pattern. A total 827 histologically proven glioma patients out 900 brain tumor who had undergone using during the period 8.5 years between July 2010 January 2019 were analyzed. Indication for harbored any evidence...
Bartonella and Borrelia are zoonotic vector-borne pathogens that can infect dogs humans. Data on in the Philippines lacking. This study was conducted to validate previous reports further investigate occurrence of spp. cities Metro Manila. A total 182 canine blood samples were acquired with DNA using a commercial extraction kit from selected veterinary clinics Manila Laguna, Philippines. The mammalian actin amplified through polymerase chain reaction (PCR), followed by PCR assays targeting...
Recent works in medical image segmentation have actively explored various deep learning architectures or objective functions to encode high-level features from volumetric data owing limited annotations. However, most existing approaches tend ignore cross-volume global context and define relations the decision space. In this work, we propose a novel voxel-level Siamese representation method for abdominal multi-organ improve The proposed enforces voxel-wise feature space leveraging datasets...