- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Luminescence and Fluorescent Materials
- Electrochemical sensors and biosensors
- Covalent Organic Framework Applications
- Molecular Sensors and Ion Detection
- Smart Grid Energy Management
- Advanced Photocatalysis Techniques
- Analytical Chemistry and Sensors
- Smart Grid and Power Systems
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Power Systems and Renewable Energy
- RNA Research and Splicing
- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
Shandong Normal University
2023-2025
Soochow University
2024
The development of highly sensitive and selective analytical approaches for monitoring enzymatic activity is critical disease diagnosis biomedical research. Herein, we develop an exogenous co-reactant-free electrochemiluminescence (ECL) biosensor the ratiometric measurement α-glucosidase (α-Glu) based on a zeolitic imidazolate framework (ZIF-67)-regulated pyrene-based hydrogen-bonded organic (HOF-101). Target α-Glu can hydrolyze maltose to α-d-glucose, which subsequently react with GOx...
Fluorogenic RNA aptamers are valuable tools for cell imaging, but they still suffer from shortcomings such as easy degradation, limited photostability, and low fluorescence enhancement. Molecular crowding conditions enable the stabilization of structure, promotion folding, improvement activity functional RNA. Based on artificial condensates, here we present a versatile platform to improve fluorogenic aptamer properties develop sensors target analyte imaging in living cells. Using CUG repeat...
We present a dimensional regulating charge transfer strategy to achieve an enhanced electrochemiluminescence (ECL) by constructing one-dimensional pyrene-based covalent organic framework (1D-COF). The dual-chain-like edge architecture in 1D-COF facilitates the stabilization of aromatic backbones, enhancement electronic conjugations, and decrease energy loss. generates anodic (92.5-fold) cathodic (3.2-fold) signals with tripropylamine (TPrA) K2S2O8 as coreactants, respectively, compared...
Ochratoxin A (OTA) is a type of mycotoxin found in various contaminated foods, and it highly toxic to the livers kidneys humans. Herein, we develop self-enhanced electrochemiluminescent (ECL) sensor based on tandem signal amplification self-luminescent europium covalent-organic polymer (Eu-COPTMT-BPA) for OTA assay. Eu-COPTMT-BPA ECL emitter that obtained by using 2,4,6-trimethyl-1,3,5-triazine (TMT) 2,2′-bipyridine-5,5′-dicarbaldehyde (BPA) as first second ligands form conjugated structure...
Abstract The porphyrin‐based hydrogen‐bonded organic framework (HOF) offers a superior platform for decoding electrochemiluminescence (ECL) via controlling charge transfer due to its higher solubility, chemical stability, and tunable behavior. In this research, three kinds of HOFs including TDPP‐HOF, TCPP‐HOF, TCNPP‐HOF are synthesized based on porphyrin tectonic plate decorated with 2,4‐diaminotriazinyl (DAT), carboxyl, nitrile moieties study their ECL performances. hydrazine as the...
We demonstrate for the first time construction of a dual-mode biosensor electrochemiluminescent (ECL) and electrochemical chiral recognition l- d-isomers amino acids, with ferrocene (Fc) as both signal enhancer tracer. With dissolved oxygen coreactant, ZnIn2S4 acts ECL emitter to generate weak cathodic signal. Fc can enter into β-cyclodextrin (β-CD) cavity on ZnIn2S4-modified electrode result host–guest interaction. Since promote H2O O2 produce abundant reactive species (ROS) (e.g., O2·–...
Luminescent materials with aggregation-induced emission (AIE) characteristics have been recognized as highly selective and sensitive probes for the detection of toxic metal ions in recent years. In this paper, a Au-Ag cluster-based coordination polymer [Au