A5092515009- Bone and Dental Protein Studies
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Metabolomics and Mass Spectrometry Studies
- Ferroptosis and cancer prognosis
- Heme Oxygenase-1 and Carbon Monoxide
- Adipose Tissue and Metabolism
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
Riga Technical University
2023-2025
Innovation (Latvia)
2024
Innsbruck Medical University
2024
Universität Innsbruck
2024
The Cell Counting Kit-8 (CCK-8) cell viability assay, also known as WST-8, is widely recognized for its nontoxic nature, making it suitable further studies on treated cells. This practice commonly observed in the field of tissue engineering. While live/dead imaging may not readily reveal macroscopic differences, our investigation has uncovered significant intracellular metabolic changes. Notably, we substantial down-regulation metabolites within glycolysis and pentose phosphate pathways....
Purpose PEXS was first described in 1917, yet its etiology still needs clarification. An imbalance between oxidants and antioxidants plays a significant role. leads to various ocular complications, including increased risk during cataract surgery due weak zonules, lens dislocation, reduced visual outcomes. Our study investigates whether metabolomics can provide insights into this pathology. Methods The included 183 patients undergoing at Pauls Stradins Clinical University Hospital. 104 did...
Calcium phosphate (CaP) based biomaterials have been widely used in hard tissue engineering. However, their impact on cell metabolism is still unclear. To investigate the cell-CaP interplay at level, we synthesized and characterized hydroxyapatite, β-tricalcium phosphate, biphasic calcium composites. We further these materials to study effects NIH/3T3 metabolic microenvironment. For this, relied LC-MS metabolomics workflow. Our results revealed that CaPs influence microenvironment by...