A5070155581- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Orthopaedic implants and arthroplasty
- biodegradable polymer synthesis and properties
- Calcium Carbonate Crystallization and Inhibition
- Bone Metabolism and Diseases
- Advanced ceramic materials synthesis
- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Bone health and osteoporosis research
- Titanium Alloys Microstructure and Properties
- Dental Radiography and Imaging
- Bone and Dental Protein Studies
- Recycling and utilization of industrial and municipal waste in materials production
- Concrete and Cement Materials Research
- Bone health and treatments
- Gas Sensing Nanomaterials and Sensors
- Facial Trauma and Fracture Management
- Endodontics and Root Canal Treatments
- Bone fractures and treatments
- Catalytic Processes in Materials Science
- Graphene and Nanomaterials Applications
- Advanced materials and composites
- Nanoparticle-Based Drug Delivery
Riga Technical University
2015-2024
Innovation (Latvia)
2015-2024
Materials Science & Engineering
2021
Riga Stradiņš University
2018
Tallinn University of Technology
2017
Amorphous calcium phosphate (ACP) is essential in formation of mineralized bone and using as a substitute. This study presents new aspects carbonated ACP crystallization during heat treatment. Initially synthesis end pH drying method (80 °C or freeze-drying) were varied. Thermal behaviour structure differently obtained evaluated DSC-TGA, heating microscopy, XRD, FT-IR. In addition, degree crystallinity (DOC), phase composition chemical group information compared for as-synthesized...
Purpose: Compositional tailoring is gaining more attention in the development of advanced biomimetic nanomaterials. In this study, we aimed to prepare multi-substituted hydroxyapatites (ms-HAPs), which show similarity with inorganic phase bones and might have therapeutic potential for bone regeneration. Materials: Novel nano substituted simultaneously divalent cations: Mg 2+ (1.5%), Zn (0.2%), Sr (5% 10%), Si (0.2%) as orthosilicate (SiO 4 4- ) were designed successfully synthesized first...
Mastering new and efficient ways to obtain successful drug delivery systems (DDS) with controlled release became a paramount quest in the scientific community. Increase of malignant bone tumors necessity optimize an approach localized require research be even more intensified. Octacalcium phosphate (OCP), number advantages over current counterparts is extensively used engineering. The aim present was synthesize bioactive biocompatible doxorubicin (DOX) containing OCP particles. DOX-OCP...
As the primary solid phase, amorphous calcium phosphate (ACP) is a pivotal precursor in cellular biomineralization. The intrinsic interplay between ACP and Howard factor underscores significance of understanding their association for advancing biomimetic development. While organic compounds play established roles biomineralization, this study presents synthesis with naturally occurring (ascorbate, glutamate, itaconate) ubiquitously found mitochondria vital bone remodeling healing. developed...
Research on biomaterials typically starts with cytocompatibility evaluation, using the ISO 10993-5 standard as a reference that relies extract tests to determine whether material is safe (cell metabolic activity should exceed 70 %). However, generalized approach within may not accurately reflect material's behavior in direct contact cells, raising concerns about its effectiveness. Calcium phosphates (CaPs) are group of materials that, despite being highly biocompatible and promoting bone...
The inflammatory-associated corrosion of metallic dental and orthopedic implants causes significant complications, which may result in the implant's failure. resistance can be improved with coatings surface treatments, but at same time, it might affect ability to undergo proper osteointegration. In this work, alginate hydrogels without octacalcium phosphate (OCP) were made on 3D-printed (patterned) titanium alloys (Ti Group 2 Ti-Al-V 23) enhance their anticorrosion properties simulated...
Amorphous calcium phosphate (ACP) is the first solid phase precipitated from a supersaturated solution. Naturally, ACP formed during initial stages of biomineralization and stabilized by an organic compound. Carboxylic groups containing compounds are known to regulate nucleation crystallization hydroxyapatite. Therefore, biomimetic point view, synthesis carboxylate ions (ACPC) valuable. Usually, synthesized with fewer steps than ACPC. The precipitation reaction rapid influenced pH,...
Osteochondral defect repair with a collagen/collagen-magnesium-hydroxyapatite (Col/Col-Mg-HAp) scaffold has demonstrated good clinical results. However, subchondral bone remained suboptimal, potentially leading to damage the regenerated overlying neocartilage. This study aimed improve potential of this by incorporating newly developed strontium (Sr) ion enriched amorphous calcium phosphate (Sr-ACP) granules (100–150 μm). Sr concentration Sr-ACP was determined ICP-MS at 2.49 ± 0.04 wt%. Then...
Despite considerable interest in amorphous calcium phosphate (ACP) bioceramics, it remains a challenge to sinter ACP high relative density. Here, for sintering of ACP, we used principles the so-called cold process. We investigated effect temperature (room temperature, 100, 120 and 150 °C) presence or absence transient liquid (20 wt. % water), while holding pressure applied at 500 MPa, on densification structure ACP. Relative density samples that were produced from dry starting powder room...
The concrete industry is eagerly pursuing the economic advantages of and improvement its long-term properties. One most effective approaches to improve properties associated with replacing part Portland cement pozzolanic additives. Although commercial pozzolans like silica fume have proven be effective, they come at a high cost. Therefore, modern construction researching pozzolan alternatives. These new could as by-products from different industries, usually accompanied by low-prices, but...
Even with decades of research studies behind octacalcium phosphate (OCP), determination OCP phase formation has proved to be a cumbersome challenge. though obtaining large quantity is important for potential clinical uses, it still remains hindrance obtain high yields pure OCP. Taking that into consideration, the purpose this study was scale-up synthesis first time and use multi-technique approach follow transformation pathway at multiple points. In present study, been synthesized from...
In the present work, seafood by-products and derivates were exploited as raw materials to produce nanocrystalline calcium phosphates-based composites in light of rising demand for waste recovery valorisation. Mussel shells transformed into hydroxyapatite by dissolution-precipitation synthesis at 45 °C, whereas chitosan from shrimp was introduced a reinforcing biopolymer hydroxyapatite/chitosan composites. The synthesised composite powders cold sintered room temperature under 1 GPa pressure...