Kah Min Tan
- Advanced Proteomics Techniques and Applications
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Molecular Biology Techniques and Applications
- Nostalgia and Consumer Behavior
- Psychology of Moral and Emotional Judgment
- Cancer Genomics and Diagnostics
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Prostate Cancer Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Cruise Tourism Development and Management
- Olfactory and Sensory Function Studies
- Diverse Aspects of Tourism Research
- Colorectal Cancer Treatments and Studies
- Language, Metaphor, and Cognition
- Cancer-related molecular mechanisms research
- Genetic factors in colorectal cancer
- Cancer Immunotherapy and Biomarkers
National Cancer Centre Singapore
2023-2024
Nanyang Technological University
2018-2020
Purpose International exchange students have been known for an often-neglected population in tourism research and their intention to revisit the host country has not explored. Accordingly, purpose of this paper is examine relationships among international students’ memorable experiences, nostalgia, satisfaction intention. Design/methodology/approach Data were collected from (N = 169) with recent experience using snowball sampling approach through various online platforms. The hypothesised...
Prostate cancer is frequently treated with radiotherapy. Unfortunately, aggressive radioresistant relapses can arise, and the molecular underpinnings of radioresistance are unknown. Modern clinical radiotherapy evolving to deliver higher doses radiation in fewer fractions (hypofractionation). We therefore analyzed genomic, transcriptomic, proteomic data characterize prostate cells both conventionally fractionated hypofractionated Independent fractionation schedule, resistance involved...
<p>Supporting data for differential RNA abundance analysis</p>
<p>Prostate cancer cohort characteristics</p>
<p>Prostate cancer cohort characteristics</p>
<p>The genomic landscape of CF- and HF-resistant prostate cancer cells. <b>A,</b> Schematic experimental design workflow. <b>B,</b> Somatic SNV count for vs. CF-resistant cells gained twice more SNVs than HF (<i>P</i> = 0.1; Mann–Whitney <i>U</i> test). <b>C,</b> in driver genes. Presented are all genes that predicted to be strongly influenced by SNVs. Considered were identified three replicates each cell type. Top,...
<p>Characteristics of radioresistance modulator candidates in primary prostate tumors. <b>A,</b> Significant associations (FDR ≤ 0.05) between CNAs candidate genes and biochemical recurrence, as shown by fitting Cox proportional hazard models ICGC. <b>B,</b><i>POLQ</i> amplification is associated with relapse ICGC (Cox model; FDR = 7.78 × 10<sup>−3</sup>). <b>C,</b> High POLQ RNA abundance BCR following an RT treatment NCCS...
<p>Supplementary genomic data</p>
<p>Supporting data for POLQ inhibition effects</p>
<p>The difference in RNA abundance of a PCNA isoform (ENST00000379143.10) and POLD1 isoforms (ENST00000440232.7 ENST00000596648.1)</p>
<p>The proteome signature upon <i>POLQ</i> inhibition. <b>A,</b> Experimental design schematic. <b>B,</b> Genetic The parental, CF-resistant, and HF-resistant cells were treated with either siRNA or scramble as the control. Significant radiosensitization was observed in all cell lines knockdown (<i>P</i> = 0.01, 0.002, 0.02 for cells, respectively; paired <i>t</i> test). Three biological replicas of 4,000 per well three 6,000...