A5101557212- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Cancer Treatment and Pharmacology
- Coronary Interventions and Diagnostics
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cardiac Imaging and Diagnostics
- Reconstructive Facial Surgery Techniques
- Estrogen and related hormone effects
- Bone fractures and treatments
- Gastric Cancer Management and Outcomes
- Cancer and Skin Lesions
- Cardiac Arrest and Resuscitation
- Microtubule and mitosis dynamics
- Colorectal Cancer Treatments and Studies
- Thermal Regulation in Medicine
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Hip and Femur Fractures
- Genetic factors in colorectal cancer
- Cardiovascular and exercise physiology
- Pelvic and Acetabular Injuries
- Cardiac pacing and defibrillation studies
- BRCA gene mutations in cancer
- Pectus Deformity Diagnosis and Treatment
Jichi Medical University
2023-2025
NTT Medical Center
2024-2025
Tochigi Cancer Center
2008-2024
University of Tokyo Hospital
2022
Juntendo University
2011-2019
The University of Tokyo
1994-2013
Tokyo Medical University
2004
Shizuoka City Shimizu Hospital
1988-1989
National Defense Academy of Japan
1968
Monolayers of endothelial cells (EC) cultured from mouse lymph nodes were exposed to controlled levels shear stress (0-7.1 dyn/cm2) in a parallel plate flow chamber, and binding between the flow-loaded EC node-derived lymphocytes was assayed. A large number adhered stationary control EC, but 1.5 dyn/cm2 for 6 h, adhesion decreased 68.8 +/- 12.8% (SD; n = 19) (n 29, P < 0.001). The decrease induced by loading time dependent reversible. Treatment with monoclonal antibody (MAb) vascular cell...
The prevalence of BRCA 1/2 germline mutations in Japanese patients suspected to have hereditary breast/ovarian cancer was examined by a multi‐institutional study, aiming at the clinical application total sequencing analysis and validation assay sensitivity people using cross‐sectional approach based on genetic factors estimated from personal family histories. One hundred thirty‐five subjects were referred counseling clinics enrolled study. Full gene showed 28 types deleterious 36 (26.7%),...
Background: The ratio of early diastolic transmitral flow velocity (E) to tissue Doppler (TD) mitral annular (E/E′ VEL‐TD ) has been widely used for the noninvasive assessment LV filling pressures. However, it reported that E/E′ is not accurate particularly when being applied patients with advanced heart failure. Methods: Fifty‐six ICU decompensated failure underwent simultaneous echocardiography and PCWP measurements. Patients elevated (n = 41) were compared normal 15) as well age‐matched...
Abstract Background Distal radius fracture (DRF) is very common worldwide. In particular, aging countries have numerous patients with DRF, resulting in an urgent need for active preventive measures. As few epidemiological studies investigated DRF Japan, we aimed to identify the characteristics of all ages Japan. Methods This descriptive epidemiologic study analyzed data obtained from clinical information diagnosed January 1, 2011, December 31, 2020, at a prefectural hospital Hokkaido, We...
Introduction : This biomechanical study evaluated the effect of screw reinsertion with a locking plate on fixation strength and stability osteosynthesis in medial tibial plateau fractures using porcine bone. Materials methods Thirty tibiae were divided into three groups: group A (underwent testing after large fragment T-shaped plate), B fixation, followed by removal all screws plates refixation same holes before testing), C once plates, holes, then testing). The translation pattern...
Although the impact of presence large circumferential pericardial effusion (LCPE) on intracoronary pressure assessment coronary artery disease (CAD) has been reported, changes in comprehensive physiology including microcirculatory system according to or absence LCPE remain unclear. This paper depicts serial physiological immediately after drainage a patient with and CAD. It is important recognize that may influence circulation, requiring careful
In order to evaluate the prognostic significance of cyclin D1 mRNA expression in mammary neoplasia, its levels were measured 97 breast cancers by reverse transcription-polymerase chain reaction (PCR) using fluorescent primer and standard RNA along with estrogen receptor (ER). The median value was 1.60 amol/microg (range, 0.01 5.63 RNA). ER detectable 70 cancer samples (72.2%) significantly higher mRNA-positive than mRNA-negative tumors (p = 0.009). Furthermore, 0.001) lower patients who...
Background: Liver metastasis from breast cancer has a poor prognosis. While there are some reports of good response rates hepatic by intra-arterial infusion chemotherapy, no phase I study including pharmacokinetic analysis been reported. We performed I/II chemotherapy using adriamycin and 5-fluorouracil to find the maximum tolerated dose rate in patients with advanced or recurrent cancer. Methods: A arterial catheter an access port was inserted into proper artery. Patients received 30 mg/m2...
A prospective randomized clinical trial was conducted to evaluate the efficacy of tamoxifen plus doxorubicin and cyclophosphamide compared tegafur-uracil as an adjuvant therapy treat node-positive premenopausal breast cancer (PreMBC).Eligibility criteria included pathologically (n = 1-9) preMBC with curative resection, in stages I-IIIA. Patients were receive either 20 mg/day 400 (TU) for 2 years or six courses a 28-day cycle 40 mg/m(2) 500 on day 1 along (ACT) given therapy. Primary endpoint...
The sternalis muscle is a vestigial that vertically long with rectangular shape, courses parallel or oblique to the axis of medial sternocostal part pectoralis major, and presents in rare cases (1.3%) [1] [2]. It often has major effect on insertion tissue expander during breast reconstruction; however, there only been single report being elevated as lower mastectomy flap, no reports have published about repairing intraoperative trauma [3].