A5087764173- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Prion Diseases and Protein Misfolding
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Hip and Femur Fractures
- Sodium Intake and Health
- Knee injuries and reconstruction techniques
- Geriatric Care and Nursing Homes
- Nutritional Studies and Diet
- Gout, Hyperuricemia, Uric Acid
- Suicide and Self-Harm Studies
- Bone fractures and treatments
- COVID-19 epidemiological studies
- Neurological diseases and metabolism
- Case Reports on Hematomas
- Emergency and Acute Care Studies
- Pelvic and Acetabular Injuries
- Blood Pressure and Hypertension Studies
- Autoimmune and Inflammatory Disorders Research
- Respiratory viral infections research
- Liver Disease Diagnosis and Treatment
- Homicide, Infanticide, and Child Abuse
Jichi Medical University
2016-2025
Japan Pediatric Society
2024
Tochigi Medical Center
2024
Nagaoka University of Technology
2024
Yamato Municipal Hospital
2024
Centers for Disease Control and Prevention
2019-2021
National Center for Emerging and Zoonotic Infectious Diseases
2019-2021
Jichi Medical University Hospital
2010-2021
Nagasaki Medical Center
2021
National Center of Neurology and Psychiatry
2020
Background: The number of patients and incidence rate Kawasaki disease (KD) are increasing in Japan. We have therefore characterized the latest epidemiological information on KD.Methods: 22nd nationwide survey KD, which targeted diagnosed with KD 2011 2012, was conducted 2013 included a total 1983 departments hospitals. In order to report all during 2 years, we hospitals 100 beds or more pediatric departments, specialized hospitals.Results: From 1420 (71.6% response rate), 26 691 were...
Approximately 50 years have passed since Kawasaki disease (KD) was first reported. The KD nationwide survey began in 1970. Although >360 000 cases already been reported Japan, the cause is still unknown. In number of patients and incidence rate has continued to increase. It necessary examine trend occurrence surveillance KD.The patient 2015 2016 conducted 2017, as 24th KD. A questionnaire sent pediatric departments hospitals with >100 beds specialized hospitals, responded by attending...
The etiology of Kawasaki disease (KD) is unknown. In Japan, the number patients and incidence rate KD has increased continuously since its discovery. aim this report was to analyze latest nationwide epidemiological survey in Japan.The 23rd conducted 2015. To on all diagnosed with 2013 2014, a questionnaire sent hospitals ≥100 beds containing pediatric departments, as well specialized hospitals.The reported 15 696 979 resulting an annual 302.5 308.0 per 100 000 population aged 0-4 years,...
To determine whether preventive trials in genetic prion disease could be designed to follow presymptomatic mutation carriers onset of disease.We assembled age at or death data from 1,094 individuals with high penetrance mutations the protein gene (PRNP) order generate survival and hazard curves test for modifiers onset. We used formulae simulations estimate statistical power clinical trials.Genetic varies over several decades most common neither sex, parent's onset, nor PRNP codon 129...
Global studies have reported that the incidence of Kawasaki disease (KD) declined during COVID-19 pandemic. These suggest global pandemic and its accompanying mitigation measures may provide an important opportunity to explore hypothesis a KD pathogenesis.To compare changes in Japan before after start pandemic.This cohort study was conducted using data set from Japan's 26th nationwide survey obtained information on patients who were diagnosed with January 1, 2019, through December 31,...
To investigate associations between socioeconomic status (SES) and prevalence, awareness, treatment, control of hypertension in Japan's general population.In 2010, we established a cohort participants the National Health Nutrition Survey Japan. The included 2623 adults from 300 randomly selected areas across Using baseline data, four cross-sectional analyses were performed: association SES with prevalent participants; unawareness no treatment 1282 hypertensive patients; uncontrolled 720...
To assess the epidemiologic association between Kawasaki disease and common pediatric infectious diseases (PIDs) identified during coronavirus 2019 (COVID-19) pandemic period to confirm whether infection-triggered theory is a plausible hypothesis for pathogenesis of disease.
Abstract Background Distal radius fracture (DRF) is very common worldwide. In particular, aging countries have numerous patients with DRF, resulting in an urgent need for active preventive measures. As few epidemiological studies investigated DRF Japan, we aimed to identify the characteristics of all ages Japan. Methods This descriptive epidemiologic study analyzed data obtained from clinical information diagnosed January 1, 2011, December 31, 2020, at a prefectural hospital Hokkaido, We...
Objectives: This study investigates the impact of xanthine oxidase inhibitors (XOI) on mortality in patients with cardiovascular diseases. XOI withdrawal has been reported to increased risk due rapid adenosine triphosphate (ATP) deficiency. aims determine whether treatment reduces and increases mortality. Methods: is a real-world database using Japanese Registry All Cardiac Vascular Diseases (J-ROAD). We analyzed 1,648,891 hospitalized aged 20–90 acute coronary syndrome or heart failure. In...
Arterio-enteric fistulas (AEFs) are a rare cause of gastrointestinal bleeding involving direct communication between an artery and the intestinal tract. The duodenum is most common fistula site for AEFs, but none rectal cases known. We present case elderly man with hematochezia due to caused by left internal iliac aneurysm, which was detected on contrast-enhanced computed tomography (CT), showing typical formation ectopic gas images. This highlights importance considering occurrence...
Juvenile-onset morphea can severely impact activities of daily living by causing functional disability. This study was performed to clarify the epidemiological and clinical characteristics juvenile-onset in Japan. We conducted a nationwide, two-part postal survey. The first survey aimed estimate number patients with morphea, while second elucidate morphea. included all ages whose age at disease onset <18 years who visited medical institution from 1 January, 2016 31 December, 2020. identified...
Background: Cardiac lesions, such as coronary dilatation, aneurysms, narrowing, myocardial infarction, and valvular sometimes occur in Kawasaki disease, but most studies have only evaluated cardiac lesions the later phase of disease. This study was undertaken to clarify related factors between laboratory data initial disease.Methods: We conducted a cross-sectional using for 26 691 patients from 22nd nationwide survey disease Japan, observation period which January 2011 through December 2012....
Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disorder that, according to the most well accepted hypothesis (1), caused by replicating, transmissible, abnormal forms of host-encoded prion protein (prions). Most CJD cases occur spontaneously (sporadic CJD) or are inherited (genetic CJD). Iatrogenic can after exposure prion-contaminated instruments products in medical/surgical settings. Cadaveric dura mater graft-associated (dCJD) accounts for common form iatrogenic CJD. This...
Since 1987, no study has reported the municipal-level geographical clustering of Kawasaki disease (KD) in Japan. Therefore, aim present was to identify temporal and KD.The annual incidence rates KD for each municipality were calculated using nationwide data from 73 758 patients with (2007-2012). To determine whether existed, we correlations during years, compared these those adjacent municipalities. Spatial scanning analysis used clusters year, surrounding region.The national rate KD,...
Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating disease caused by JC virus (JCV), predominantly affecting patients with impaired cellular immunity. PML non-reportable few exceptions, making national surveillance difficult. In Japan, polymerase chain reaction (PCR) testing for JCV in the cerebrospinal fluid (CSF) performed at National Institute of Infectious Diseases to support diagnosis. To clarify overall profile patient data provided time CSF-JCV over 10...
Abstract Background Although the incidence rates of Kawasaki disease ( KD ) in Japan have been determined nationwide surveys, cumulative incidence, that is, proportion those with a history general population 10‐year‐olds, is currently unknown. The aim this study was therefore to assess Japan. Methods Using age‐ and sex‐specific rate from results probabilities, age‐specific number patients divided by used vital statistics, proportions not affected up end 9 years age, were calculated. then...
Objective To clinically diagnose MM2-cortical (MM2C) and MM2-thalamic (MM2T)-type sporadic Creutzfeldt-Jakob disease (sCJD) at early stage with high sensitivity specificity. Methods We reviewed the results of Surveillance Study in Japan between April 1999 September 2019, which included 254 patients pathologically confirmed prion diseases, including 9 MM2C-type sCJD (MM2C-sCJD) 10 MM2T-type (MM2T-sCJD), 607 non-prion diseases. Results According to conventional criteria sCJD, 4 MM2C- 7...
Background Detection of coronary artery lesions (CALs) at initial echocardiography can aid in diagnosing Kawasaki disease (KD) and inform primary adjunctive treatments. We aimed to characterize patients with KD CALs detected echocardiography. Methods Results analyzed data from the nationwide Japanese survey that contained information on 103 222 population-based diagnosed across Japan during 2011 2018. Patients were assessed by age, day illness, number principal signs (≥3). Multivariable...
The decision whether to measure night-time blood pressure (BP) is challenging as these values cannot be easily evaluated because of problems with measurement devices and related stress. Using the nationwide, practice-based Japan Morning Surge-Home BP Nocturnal study data, we developed a simple predictive score that physicians can use diagnose nocturnal hypertension.We divided 2765 outpatients (mean age 63 years; hypertensive patients 92%) cardiovascular risks who underwent morning, evening,...