Jacob Singer

ORCID: 0009-0001-0890-2733
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About
Contact & Profiles
Research Areas
  • Advanced Neuroimaging Techniques and Applications
  • Neurological Disease Mechanisms and Treatments
  • Pleural and Pulmonary Diseases
  • Esophageal and GI Pathology
  • Lung Cancer Diagnosis and Treatment
  • Mycobacterium research and diagnosis
  • Diagnosis and treatment of tuberculosis
  • Tuberculosis Research and Epidemiology
  • Historical and Linguistic Studies
  • Medical Imaging and Pathology Studies
  • Knee injuries and reconstruction techniques
  • Biblical Studies and Interpretation
  • Tracheal and airway disorders
  • Virology and Viral Diseases
  • Infectious Diseases and Tuberculosis
  • Circular RNAs in diseases
  • Cystic Fibrosis Research Advances
  • Control and Dynamics of Mobile Robots
  • Mesenchymal stem cell research
  • Radiology practices and education
  • Osteoarthritis Treatment and Mechanisms
  • Otolaryngology and Infectious Diseases
  • Biomarkers in Disease Mechanisms
  • Ideological and Political Education
  • Legal and Constitutional Studies

Steadman Philippon Research Institute
2024-2025

Texas A&M Health Science Center
2025

Texas A&M University
2025

Singer (United States)
2024

University of Minnesota
2024

Naval Hospital Pensacola
2016

United States Department of the Navy
2016

St. John's University
2011

10.1097/00000441-193506000-00014 article EN The American Journal of the Medical Sciences 1935-06-01

10.1016/s0096-5588(20)32564-2 article Journal of Thoracic Surgery 1931-12-01

ABSTRACT Our previous studies showed that intravenous injections of the small non-coding RNA mir-20a-3p is neuroprotective for stroke in acute phase and attenuates long-term cognitive impairment middle-aged female rats. In this study, we evaluated postmortem brain pathology at 100+d after a set behaviorally characterized animals. This included Sham (no stroke) controls or animals received either mir20a-3p 4h, 24h 70d iv post (MCAo+mir20a-3p) scrambled oligo (MCAo+Scr). Brain volumetric...

10.1101/2025.02.01.636074 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2025-02-06

Abstract Anterior cruciate ligament (ACL) injury adversely affects skeletal muscle, leading to muscle atrophy and weakness, significantly impacting clinical outcomes. This study aimed determine if estrogen‐related receptor gamma (ERRγ) overexpression in could mitigate after ACL injury. An animal model with selective of ERRγ (ERR‐gamma transgenic mice, TG) WT control mice were used for this study. All the received a mechanical rupture euthanized at 4‐ 8‐week post‐injury. Muscle histology,...

10.1096/fj.202402021r article EN The FASEB Journal 2025-02-18

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are well established for their osteogenic potential but prone to senescence with aging or in vitro expansion. Drug treatments that reduce cellular may enhance the regenerative capacity of BM-MSCs. This study investigates effects losartan and fisetin, both separately combination, on osteogenesis. Human BM-MSCs were exposed low high concentrations each drug 24 h. Our findings showed high-dose exhibited cytotoxicity, focusing subsequent...

10.1155/term/9187855 article EN cc-by Journal of Tissue Engineering and Regenerative Medicine 2025-01-01

In the study of roentgenograms chest patients who have had a bismuth or barium meal for gastro-intestinal study, one occasionally encounters startling picture bronchi outlined by barium. This accident is due to fistulous tract caused ulceration esophagus into trachea. It has been noticed in these that fits coughing occur during swallowing We learned look suddenly begin cough examination. Jackson 1 Philadelphia introduced subcarbonate finely powdered form through bronchoscope lobe lung he...

10.1001/archsurg.1927.01130130171008 article EN Archives of surgery 1927-01-01

Since the introduction of use iodized oil by Sicard and Forestier,<sup>1</sup>many uses have been found for in roentgen-ray study lungs pleura. The methods described originators are complicated require unusual, expert skill intratracheal instruments. While there can be no objection to that outlined various authors, it seems simplest method would obviate bronchoscope instruments many cases. In a communication Lian, Darbois Navarre<sup>2</sup>in 1922, was suggested could aspirated into pulling...

10.1001/jama.1926.92680160001013a article EN JAMA 1926-10-16

The recent literature on lung abscess reveals two very important facts: (1) the increasing recognition of importance tonsillectomy as a causative factor in production abscess, and (2) apparently marked increase general incidence condition. operation seems to be most likely followed by when it is performed under anesthesia. Lockwood,<sup>1</sup>for example, study fifty-four cases seen at Mayo Clinic, considered that sixteen were due tonsillectomy, all but one which had been...

10.1001/jama.1923.02650030017005 article EN JAMA 1923-07-21

We investigated the efficiency of target-enriched long-read sequencing (TELSeq) for detecting antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs) within complex matrices. aimed to overcome limitations associated with traditional (AMR) detection methods, including short-read shotgun metagenomics, which can lack sensitivity, specificity, ability provide detailed genomic context. By combining biotinylated probe-based enrichment sequencing, we facilitated amplification ARGs,...

10.1101/gr.279226.124 article EN cc-by-nc Genome Research 2024-11-01

10.3322/canjclin.24.4.238 article EN CA A Cancer Journal for Clinicians 1974-07-01

10.1016/s0096-5588(20)32539-3 article publisher-specific-oa Journal of Thoracic Surgery 1932-06-01

10.1016/s0096-5588(20)32558-7 article publisher-specific-oa Journal of Thoracic Surgery 1932-02-01

10.1097/00000441-191804000-00004 article EN The American Journal of the Medical Sciences 1918-04-01

10.1016/s0096-5588(20)32546-0 article publisher-specific-oa Journal of Thoracic Surgery 1932-04-01

The use of a brominized oil as contrast medium in roentgenology has been suggested order to overcome certain dangers which are supposed be inherent iodized oils. Several manufacturers have made preparations and put them out under various names. Our experience with this type limited but sufficient give us impressions. In view the fact that other investigators statements is likely produce an aggravation symptoms signs tuberculous patients, we thought it advisable review our statistics...

10.1001/archsurg.1929.01150060722040 article EN Archives of surgery 1929-12-01

It is our desire to present a series of cases which illustrate not only certain interesting conditions but also details methods handling such here. We wish emphasize the importance an approach all chest according plan cooperation between medical and surgical services. For nearly ten years we have been associated in organization development service for this group hospitals. meet almost daily discuss patients who may possibly any chest. The mutual those with point view on many these most...

10.1001/archsurg.1929.01150060614030 article EN Archives of surgery 1929-12-01

10.1016/s0096-5588(20)32491-0 article EN publisher-specific-oa Journal of Thoracic Surgery 1936-02-01

During the past few years, there have been many important advances in diagnostic method of thoracic conditions. Among more valuable additions may be mentioned use iodized oil and pneumothorax. Scarcely less is selection position most favorable for obtaining information fluoroscopic roentgen examination. Any one or all new methods applicable individual patient. It has possible us to combine these a satisfactory manner because existence chest service Barnes Hospital where specially trained...

10.1001/archsurg.1929.04420020105006 article EN Archives of surgery 1929-01-01

10.1097/00007611-192702000-00012 article EN Southern Medical Journal 1927-02-01

Introduction: Our earlier studies show that the small non-coding RNA, mir20a-3p, is neuroprotective after stroke, and reduces sensory-motor impairments in acute phase cognitive decline long-term female rats. Cognitive due to vascular diseases, such as associated with volume loss cortex, limbic structures white matter tracts. In this study, we examined of forebrain tracts, cortical animals characterized impairment efficacy microRNA treatment. Methodology: Middle-aged females were subjected...

10.1161/str.55.suppl_1.wp323 article EN Stroke 2024-02-01

Background: The field of orthobiologics traditionally utilizes cellular products, including bone-marrow aspirate concentrate (BMAC), micronized adipose tissue, and platelet preparations to address pain from degenerative processes, orthopedic injuries medical conditions characterized by chronic inflammation tissue degradation. For BMAC, maximizing the concentration mesenchymal stem cells (MSCs) in a reduced volume is thought allow for therapeutic delivery concentrate, secretome, extracellular...

10.22374/boj.v6i1.61 article EN cc-by Biologic Orthopedics Journal 2024-04-24
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