Tianchen Xie

ORCID: 0009-0001-2288-640X
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Research Areas
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Venous Thromboembolism Diagnosis and Management
  • Renal and Vascular Pathologies
  • Infectious Aortic and Vascular Conditions
  • Vascular Procedures and Complications
  • Central Venous Catheters and Hemodialysis
  • Diagnosis and Treatment of Venous Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Advanced X-ray and CT Imaging
  • Atrial Fibrillation Management and Outcomes
  • Coronary Interventions and Diagnostics
  • Abdominal vascular conditions and treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Valve Diseases and Treatments
  • Layered Double Hydroxides Synthesis and Applications
  • Environmental Toxicology and Ecotoxicology
  • Tropical and Extratropical Cyclones Research
  • Marine Biology and Environmental Chemistry
  • Protease and Inhibitor Mechanisms
  • Circular RNAs in diseases
  • Evacuation and Crowd Dynamics
  • Sports Analytics and Performance
  • Advanced Text Analysis Techniques
  • Flood Risk Assessment and Management

Fudan University
2020-2024

Zhongshan Hospital
2020-2024

Beijing University of Civil Engineering and Architecture
2024

Nanjing Normal University
2019

Background Integrin αM (CD11b), which is encoded by the Subunit Alpha M (ITGAM) gene, not only a surface marker of monocytes but also an essential adhesion molecule. In this study, we investigated effect CD11b on experimental abdominal aortic aneurysm and potential underlying mechanisms. Methods Results The incidence was significantly lower in ITGAM(-/-) mice than control mice. Nevertheless, knockout reduced maximum diameter, macrophage infiltration, matrix metalloproteinase-9 expression,...

10.1161/jaha.120.019900 article EN cc-by-nc-nd Journal of the American Heart Association 2021-03-20

Abstract Background This study aimed to identify the differentially expressed circular RNAs (circRNAs) between human abdominal aortic aneurysm (AAA) and control group. Methods High-throughput sequencing was applied determine circRNA expression profiles of 4 paired samples. Real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) carried out testify 6 randomly selected dysregulated circRNAs. Kyoto Encyclopedia Genes Genomes Gene ontology (GO) analysis were conducted...

10.1186/s12872-020-01374-8 article EN cc-by BMC Cardiovascular Disorders 2020-02-10

Against the backdrop of increasingly severe global climate change, risk rainstorm-induced waterlogging has become primary threat to safety historic and cultural districts worldwide. This paper focuses on Beijing, China, explores techniques methods for identifying extreme rainstorm warnings in heritage areas. Refined warning forecasting have important non-engineering measures enhance these districts’ prevention control emergency management capabilities. constructs a model tailored Beijing’s...

10.3390/w16091290 article EN Water 2024-04-30

This study aimed to develop a deep learning model for predicting distal aortic remodeling after proximal thoracic endovascular repair (TEVAR) in patients with Stanford type B dissection (TBAD) using computed tomography angiography (CTA).

10.1177/15266028231160101 article EN Journal of Endovascular Therapy 2023-03-16

Endovascular aortic aneurysm repair (EVAR) is currently established as the first-line treatment for anatomically suitable abdominal (AAA).To establish a deep convolutional neural networks (DCNN) model fully automatic segmentation intraluminal thrombosis (ILT) of (AAA) in pre-operative computed tomography angiography (CTA) images.We retrospectively reviewed 340 patients AAA with ILT at our single center. The software ITKSNAP was used to draw and region interests (ROIs), respectively. Image...

10.3233/thc-thc213630 article EN Technology and Health Care 2022-03-22

Objective This study aimed to develop a radiomics model predict the outcome of endovascular aneurysm repair (EVAR) for abdominal aortic (AAA), based on machine learning (ML) algorithms. Methods We retrospectively reviewed 711 patients with infra-renal AAA who underwent elective EVAR procedures between January 2016 and December 2019 at our single center. The features were extracted using Pyradiomics. Pearson correlation analysis, analysis variance (ANOVA), least absolute shrinkage, selection...

10.1177/17085381221091061 article EN Vascular 2022-04-19

Abstract Thrombospondin‐2 (Tsp2), a glycoprotein in the extracellular matrix, plays critical role maintenance of vascular homeostasis. However, its pathogenesis cardiovascular disorders such as intimal hyperplasia is not fully elucidated. This study, therefore, aims to explore effect Tsp2 on and associated underlying mechanisms. Intimal (IH) was established using modified wire‐mediated femoral artery injury model. Immunofluorescence qPCR identified upregulated expression injured compared...

10.1096/fj.202201040r article EN The FASEB Journal 2023-01-16

Sac regression (SR) is a surrogate marker of satisfied endovascular aneurysm repair (EVAR). This research aims to investigate the incidence and predictors SR in Chinese population. Single centre retrospective cohort study. Consecutive patients with infrarenal abdominal aortic aneurysms (AAAs) who underwent standard EVAR were retrospectively reviewed. was defined as sac shrinkage > 5 mm on computed tomography images, while major (MaSR) ≥ 10 shrinkage. The cumulative rate calculated by...

10.1016/j.asjsur.2024.01.141 article EN cc-by-nc-nd Asian Journal of Surgery 2024-02-24

With the rising impact and economic benefits of online gaming industry, companies need to understand players’ behavior evaluate their products better adjust developing strategy. This paper uses machine learning models predict behaviors. The study utilizes dataset from Kaggle, which contains 40,034 samples with 13 features related player demographics, game preferences, gameplay primary objective is classify two target variables: ‘EngagementLevel’ ‘InGamePurchases.’ Data preprocessing steps...

10.61173/5hthrr73 article EN Science and Technology of Engineering Chemistry and Environmental Protection 2024-10-29

Objective This study used unsupervised machine learning (UML) cluster analysis to explore clinical phenotypes of endovascular aortic repair (EVAR) for abdominal aneurysm (AAA) patients based on radiomics. Method We retrospectively reviewed 1785 with infra-renal AAA who underwent elective EVAR procedures between January 2010 and December 2020. Pyradiomics was extract the radiomics features. Statistical applied determine features that related severe adverse events (SAEs) after EVAR. The...

10.1177/17085381241262575 article EN Vascular 2024-06-17

The efficacy and safety of anticoagulant treatment is not established for patients with acute symptomatic isolated distal deep vein thrombosis (IDDVT). In real-world clinical practice, both therapeutic prophylactic anticoagulation are used IDDVT. However, associated higher risk bleeding than anticoagulation. Thus, this study aims to assess the in first IDDVT treated or using rivaroxaban.This a prospective, multicentre, single-blind, randomised controlled trial. Outpatients first, acute,...

10.1136/bmjopen-2021-056826 article EN cc-by-nc BMJ Open 2022-02-01

Endovascular treatment is being increasingly used for celiac artery aneurysms (CAAs), but systematic endovascular strategies have not been defined yet. This study intended to investigate the of management CAAs according a single-center experience.Anatomically, were classified into two types: Type I located in main trunk artery. II on branches and can be further divided different subtypes fusiform (a) or saccular (b) morphology: type Ia, Ib, IIa, IIb. Patient demographics, clinical...

10.1177/17085381211032768 article EN Vascular 2021-07-15

This study aimed to evaluate the postoperative and intermediate outcomes of thoracic endovascular aortic repair (TEVAR) in patients with end-stage renal disease (ESRD).We retrospectively reviewed type B dissection (TBAD) undergoing TEVAR at our single center from January 2010 December 2020. Patients pre-existing ESRD were enrolled as group. One hundred consecutive September 2013 March 2015 without included control The primary secondary adverse events survival, respectively. Kaplan-Meier...

10.1177/17085381221112550 article EN Vascular 2022-07-05

To the Editor: Iliac vein compression syndrome (IVCS) is a well-documented anatomic abnormality characterized by of iliac veins from adjacent artery and vertebra. Depending on whether deep thrombosis was co-existing, IVCS could be classified into thrombotic nonthrombotic lesions. Endovascular procedures have become mainstream treatment for IVCS.[1] In most cases, balloon dilation insufficient to treat because venous wall easily recoiled. Stenting lesion therefore necessary keeping...

10.1097/cm9.0000000000002522 article EN cc-by-nc-nd Chinese Medical Journal 2023-02-07

PURPOSE: The efficacy of intravascular ultrasound (IVUS) in diagnosing obstructive venous lesions has been established the Western countries; however, its beneficial role Asian population is seldom reported. Because IVUS still not widely used China, we, therefore, investigated whether salutary effect on diagnosis and treatment iliac outflow obstructions could also be extended to Chinese population.MATERIALS AND METHODS: This was a prospective single-center study. Patients with nonthrombotic...

10.4103/vit.vit_26_20 article EN cc-by-nc-sa Vascular Investigation and Therapy 2020-01-01
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