A5101928429- Escherichia coli research studies
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Immunotherapy and Immune Responses
- Animal Disease Management and Epidemiology
- Clostridium difficile and Clostridium perfringens research
- Viral Infections and Immunology Research
- Antibiotic Resistance in Bacteria
- Aquaculture disease management and microbiota
- Salmonella and Campylobacter epidemiology
- CAR-T cell therapy research
- Gut microbiota and health
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Vector-Borne Animal Diseases
- Probiotics and Fermented Foods
- Marine Toxins and Detection Methods
- Potato Plant Research
- Oxidative Organic Chemistry Reactions
- Viral Infectious Diseases and Gene Expression in Insects
- RNA Interference and Gene Delivery
- Alkaloids: synthesis and pharmacology
- Cancer Immunotherapy and Biomarkers
- vaccines and immunoinformatics approaches
- Listeria monocytogenes in Food Safety
University of Dhaka
2023-2024
BRAC University
2023-2024
Catholic Medical Center
2006-2007
New York Medical College
2006-2007
Saint Vincent's Catholic Medical Center
2006-2007
International Centre for Diarrhoeal Disease Research
1984-2006
Kuwait University
2005
Diarrheal diseases are highly prevalent in Bangladesh. However, the relative contribution of diarrheagenic Escherichia coli organisms--those that enterotoxigenic (ETEC), enteropathogenic (EPEC), enteroinvasive, enterohemorrhagic, enteroaggregative, and diffuse adherent--to diarrhea Bangladeshi populations is not known. With DNA probes specific for these E. strains, we analyzed fecal from 451 children up to 5 years age with acute seeking treatment at a Dhaka hospital 602 matched control...
Hafnia alvei, a member of the family Enterobacteriaceae, was only species bacteria cultured from stool 9-month-old child who admitted with 3-day history watery diarrhea. The isolated strain H. alvei failed to produce heat-labile or heat-stable enterotoxins Shiga-like toxin I II and did not invade HeLa cells, nor it cause keratoconjunctivitis (determined by Sereny test) in guinea pig's eye. strain, however, induced diarrhea 8 12 adult rabbits removable intestinal ties (removable tie-adult...
ABSTRACT Sixty-six strains of Vibrio parahaemolyticus belonging to 14 serotypes were isolated from hospitalized patients in Dhaka, Bangladesh, January 1998 December 2000. Among these, 48 four had the pandemic genotype and possessed tdh gene. A marker (open reading frame ORF8) for a filamentous phage previously thought correspond was found have poor correlation with genotype.
Providencia alcalifaciens is a member of the family Enterobacteriaceae. There are reports that P. can cause diarrhea, but mechanism(s) by which it causes diarrhea known. We studied isolated from child and two adults with for enteropathogenicity. The three isolates did not exhibit any characteristic adherence to cultured HEp-2 cell monolayers, they produce enterotoxins, cytotoxins, or keratoconjunctivitis in Sereny test. Two invaded producing localized bacterial clusters actin condensation....
Objectives: The aim of the present study was to determine clonal relationships ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated from south Asia, and S. associated with epidemics in 1978, 1984 1994.
ABSTRACT Of 469 recently isolated Shigella flexneri strains, 452 agglutinated with -specific monoclonal antibodies. these, 396 could be assigned to 10 of the currently recognized 15 serotypes, S. 2b dominating (23.2%). 56 untypeable strains which showed invasive properties, 17 were serologically atypical and remaining 39 belonged a new serotype.
Foot-and-Mouth Disease (FMD) hinders the growth of livestock industry in endemic countries like Bangladesh. The management and prevention FMD are severely impacted by high mutation rate subsequent frequent generation newer genotypes causative agent, Virus (FMDV). current study was conducted nine districts Bangladesh during 2019-21 to characterize circulating FMDV strains based on VP1 sequence analysis, major antigenic recognition site providing serotype specificity variability FMDV. This...
Foot-and-mouth disease (FMD) in cloven-hoofed animals is considered an economically devastating endemic countries like Bangladesh, where the livestock sector contributes to a greater portion of nation’s economy. The causative agent disease, foot-and-mouth virus (FMDV), equipped with higher mutational frequency challenges efficacy existing vaccine and control measures. This study, including 32 districts 71 outbreaks reveal epidemiological patterns trends FMDV over past 10 years (2012–2021),...
ABSTRACT A total of 358 Shigella dysenteriae strains isolated from patients attending the Dhaka treatment center International Centre for Diarrheal Disease Research, Bangladesh, between years 1999 and 2002 were included in this study. S. type 1, dominant serotype (76.4%), declined to 6.5% 2002. On other hand, types 2 12 with increasing frequencies 19, 67, 73.5, 87% 1999, 2000, 2001, 2002, respectively. Of these, 4 most serotypes, accounting more than 18.7 28.5% isolates, There was no...
Summary Vibrio mimicus , a newly described species of the genus has been isolated from stools 14 patients with diarrhoea. Live cells all strains tested caused accumulation fluid in rabbit gut loops and diarrhoea infant rabbits. Culture filtrates increased capillary permeability skin; however, five resembled cholera toxin that they gave positive reactions loops, chinese hamster ovarian mouse adrenal cell monolayers GM 1 ELISA tests were neutralized by antitoxin. None produced heat‐stable or...
In previous studies with strains of the Shigella dysenteriae provisional serovars E22383 and E23507 from diarrhoeal stools patients in Bangladesh, two species were identified as boydii serovar E16553 by a reference laboratory. Further tests an antiserum to international type strain additional 15 isolates. None isolates reacted antisera established or any other reported so far all showed biochemical reactions typical S. . All harboured 140 MDa invasion plasmid, had ipaH gene produced...
Clinical characteristics and serotype distribution of Campylobacter jejuni coli isolated from paediatric diarrhoeic patients over a three-year period in two geographically diverse areas, Dhaka, Bangladesh, Cape Town, South Africa, were compared. Both Dhaka Town had similar rates diarrhoea, vomiting fever. However, the younger (11.8 vs. 13.0 months), more boys than girls infected (male/female ratio 1.78:1 1.25:1), predisposing conditions (26% 15%) additional stool pathogens co-isolated with...
Traditional enteropathogenic Escherichia coli serotypes demonstrate a plasmid-mediated localized adherence in cultured HeLa or HEp-2 cells and induce an attaching-effacing intestinal lesion, both of which are considered pathognomonic causes diarrhea. This study describes three E. strains from infantile diarrhea share these properties but belong to (O2:H2, O2:H25 O15:H2) not enteropathogenic.
Dendritic cells (DCs) possess the unique abilities to initiate a primary immune response and present antigens naïve T lymphocytes. Recently, there has been rapidly growing interest in use of DCs active specific immunotherapy (ASI) for treatment patients with cancer. In study, we determined ability express Melanoma-Associated Antigens (MAAs) from polyvalent Melanoma Vaccine (DC-MelVac; Patent# 11221/5) developed our facility. The vaccine consists recombinant IL-2 gene-encoded vaccinia...
Six exotic potato genotypes named Actrice, Cereza, Margarita, Messi, Picobella, and Sunred, along with four check varieties, were evaluated at different locations (agroecological region) of Bangladesh in three consecutive years, 2016-17 to 2018-19 respectively find out some stable for commercial cultivation Bangladesh.Combined analysis variance showed a highly significant difference among the genotypes, locations, GEI all characters studied.None found suitable early harvesting (65 DAP), but...
Live and boiled cells of 16 strains Aeromonas caviae, isolated from patients with diarrhea, agglutinated Shigella boydii 5 antiserum in a slide test. Further studies seven selected showed agglutination tube Lipopolysaccharide antigen extracted one these cross-reacted S. enzyme-linked immunosorbent assay immunoblot studies. Either all or the majority possessed properties deemed to be diarrheagenic.