A5040799794- Phytochemicals and Antioxidant Activities
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Autophagy in Disease and Therapy
- Biochemical Analysis and Sensing Techniques
- Endoplasmic Reticulum Stress and Disease
- Adipose Tissue and Metabolism
- Hippo pathway signaling and YAP/TAZ
- Microtubule and mitosis dynamics
- Ziziphus Jujuba Studies and Applications
Tianjin University of Traditional Chinese Medicine
2025
Jinzhou Medical University
2023
Wannan Medical College
2019-2022
Upstream-stimulating factor 1 (USF1) is a ubiquitously expressed transcription implicated in multiple cellular processes, including metabolism and proliferation. This study focused on the function of USF1 glycolysis malignant development prostate adenocarcinoma (PRAD). Bioinformatics predictions suggested that poorly PRAD. The clinical PRAD samples revealed low level USF1, which was correlated with an unfavorable prognosis. Artificial upregulation significantly repressed glycolytic activity...
Abstract Activity of transcriptional co‐activator with PDZ binding domain (TAZ) protein is strongly implicated in the pathogenesis human cancer and influenced by tumor metabolism. High levels lactate concentration microenvironment as a result metabolic reprogramming are inversely correlated patient overall survival. Herein, we investigated role regulation activity TAZ showed that glycolysis‐derived efficiently increased expression lung cells. We reactive oxygen species (ROS) generated...