A5104491313- Phytochemicals and Antioxidant Activities
- Immune cells in cancer
- Rheumatoid Arthritis Research and Therapies
- Traditional Chinese Medicine Analysis
- Biochemical Analysis and Sensing Techniques
- Ziziphus Jujuba Studies and Applications
- Natural product bioactivities and synthesis
- Long-Term Effects of COVID-19
- Metabolomics and Mass Spectrometry Studies
- Genomics, phytochemicals, and oxidative stress
- Chromatography in Natural Products
- Inflammasome and immune disorders
- Aldose Reductase and Taurine
- Phytochemistry and Biological Activities
- Plant biochemistry and biosynthesis
- Phagocytosis and Immune Regulation
- Medicinal Plants and Bioactive Compounds
- Toxin Mechanisms and Immunotoxins
- Biochemical Acid Research Studies
- Retinal Diseases and Treatments
- Cytokine Signaling Pathways and Interactions
- Ion Channels and Receptors
- Advancements in Battery Materials
- Monoclonal and Polyclonal Antibodies Research
- Retinoids in leukemia and cellular processes
Tianjin University of Traditional Chinese Medicine
2022-2025
Nanjing Forestry University
2025
Affiliated Zhongshan Hospital of Dalian University
2017-2022
Wenzhou Medical University
2021
Dongyang People's Hospital
2021
Wuhan No. 7 Hospital
2018
Jinzhou Medical University
2016
Dalian University of Technology
2015
Abstract Increasing evidence suggests that n-hexane induces nerve injury via neuronal apoptosis induced by its active metabolite 2,5-hexanedione (HD). However, the underlying mechanism remains unknown. Studies have confirmed pro-nerve growth factor (proNGF), a precursor of mature (mNGF), might activate apoptotic signaling binding to p75 neurotrophin receptor (p75NTR) in neurons. Therefore, we studied proNGF/p75NTR pathway HD-induced apoptosis. Sprague–Dawley (SD) rats were injected with 400...
Platycodonis Radix (PR), a widely consumed herbal food, and its bioactive constituents, platycodins, have therapeutic potential for lung inflammation. Transient Receptor Potential Ankyrin 1 (TRPA1), which is essential the control of inflammation, may be involved in development inflammation lungs. The aim this study was to determine TRPA1-targeted effects PR against pulmonary investigate affinity constituents TRPA1 their mechanisms action. Using C57BL/6J mouse lipopolysaccharides (LPS)...
The goji berry is widely used as tonics; however, the antihuman cervical carcinoma effect and underlying mechanism of peptide remain to be elucidated. cyclic peptides are appealing targets in antitumor agent development, current study, three novel (GCPs) were isolated amino acid sequence identified. Among them, GCP-1 (Cycle-(Trp-Glu-His-Thr)) inhibited proliferation induced human cancer (HeLa) cells apoptosis blocked HeLa G0/G1 phase significantly. Furthermore, also growth vivo. Moreover,...
Abstract Zhujing pill (ZP) is a famous Chinese herbal formula that has been widely used to treat diabetic retinopathy, macular degeneration, retinitis pigmentosa and other fundus lesions. In this study, the material basis mechanism of ZP in treatment lesions were evaluated via high‐performance liquid chromatography fingerprint, ultra‐performance quadrupole time‐of‐flight mass spectrometry, network pharmacology molecular docking. A total 32 common components found 31 identified 15 batches...
Objective: This study aims to explore the clinical efficacy of CpG-based therapy for treating hepatocellular carcinoma (HCC) by skewing polarization toward M1 macrophage from M2. Methods: Pulmonary metastasis rate, overall survival time, and remission rate 10 patients with HCC treated transcatheter arterial chemoembolization (TACE) combined CpG age-, gender-, TNM0-matched TACE (control group) were compared. Results: No pulmonary was 70% in treatment group 40% control group, respectively;...
Objective To determine the effect of interleukin (IL)-17 on proliferation fibroblast-like synoviocytes (FLSs) from rheumatoid arthritis (RA)patients and to investigate whether signal transducer activator transcription 3 (STAT3) was implicated in this process. Methods FLSs were acquired by primary culturing RA patients. STAT3, p-STAT3, Bcl-2 Bax expression FLSs determined using western blotting analysis. The MTT assay. Analysis variance used differences between two...
Objective To explore the role of macrophage in development rheumatoid arthritis(RA) by systemic depletion macrophages with Clodronate liposomes(Clo-lip). Methods The spleens mice was detected hematoxylin and eosin(HE) staining immunohistochemistry.30 BALB/c were randomly divided into three groups: RA-model established as control A group; RA modelmice PBS-lip B group Clo-lip C group, which administered lips.The appearance mouse pawswere observed degree arthritis recorded histological...