A5022639223- Lung Cancer Research Studies
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Cancer Treatment and Pharmacology
- Chemotherapy-related skin toxicity
- Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Lung Cancer Treatments and Mutations
- CNS Lymphoma Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- PI3K/AKT/mTOR signaling in cancer
- Lung Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Cancer Immunotherapy and Biomarkers
Hospital Universitario Reina Sofía
2023-2024
Instituto Maimónides de Investigación Biomédica de Córdoba
2023
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common entity (30%–40%) and can significantly limit the quality of life patients, especially those that persist for more than 6 months after treatment (chronic neuropathy). Studies have shown possible association between presence genetic polymorphisms in ABCB1 development acute CIPN, although this relationship with chronic CIPN remains unexplored. This an analytical observational case-control study defined by (cases) or...
<title>Abstract</title> Introduction Palliative WBRT is the main treatment for multiple BM. Recent studies report no benefit in survival after compared to palliative supportive care patients (pts) with poor prognosis. A new era of systemic strategies based on targeted therapies are improving prognosis The purpose this study develop a prognostic score pts BM who undergo setting. Methods 239 received between 2013–2022 our center were analyzed retrospectively. was designed according value β...
e13165 Background: Invasive lobular (L) breast carcinomas (BC), which account for up to 15% of all BC, had particularly histopathological characteristics: tends be estrogen/progesterone receptor positive and HER2-neu negative as such are treated with endocrine therapy (ET). It been demonstrated a frequent activation PI3K–AKT–mTOR signaling in LBCs, suggesting this pathway promising therapeutic target LBC. Interestingly, some these patients, the subsequent use mTOR inhibitor (everolimus)...
e24154 Background: Palliative WBRT has been the main treatment for multiple brain metastases (BM). Recent studies report no benefit in survival or quality of life compared to palliative supportive care patients (pts) with poor prognosis. Several scores have developed support decision-making selection patients; despite this, scales implemented so far do not consider substantial impact new developments recent years. The purpose this study was develop and statistically validate a prognostic...
e24097 Background: Anti-tumor therapy is the most frequent cause of toxic neuropathy in Western population. Unlike its acute presentation (AN), chronic appears during treatment and persists for more than six months after end chemotherapy, significantly limiting quality life many patients. Although it a drug-dependent toxicity, there scarce evidence about frequency factors that are determinant development. The main objetive to know incidence NPCIQ as well identify predispose appearance....