A5101743813- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Peptidase Inhibition and Analysis
- Supramolecular Self-Assembly in Materials
- Cardiac Ischemia and Reperfusion
- Luminescence and Fluorescent Materials
- CAR-T cell therapy research
- Neuroblastoma Research and Treatments
- Anesthesia and Neurotoxicity Research
- Leaf Properties and Growth Measurement
- Retinoids in leukemia and cellular processes
- Corneal surgery and disorders
- Fungal Infections and Studies
- Bamboo properties and applications
- Nanowire Synthesis and Applications
- Plasma and Flow Control in Aerodynamics
- Cancer Mechanisms and Therapy
- Metabolomics and Mass Spectrometry Studies
- Natural Fiber Reinforced Composites
- Biomimetic flight and propulsion mechanisms
- Ferrocene Chemistry and Applications
- Advanced Glycation End Products research
- Chromatin Remodeling and Cancer
- Antifungal resistance and susceptibility
- ATP Synthase and ATPases Research
Zhujiang Hospital
2021-2025
Southern Medical University
2021-2025
Guangxi University
2025
Nanfang Hospital
2022
It is challenging to construct high-performing excimer-based luminescent analytic tools at low molecular concentrations. We report that enzyme-instructed self-assembly (EISA) enables the monomer-excimer transition of a coumarin dye (Cou) concentrations, and resulting higher ordered supramolecular assemblies (i.e., nanofibers) efficiently record spatiotemporal details alkaline phosphatase (ALP) activity in vitro vivo. Cou was conjugated short peptides with hydrophilic ALP-responsive group. By...
Abstract Purpose This study aimed to evaluate the safety and efficacy of chimeric antigen receptor (CAR) disialoganglioside 2 (GD2)-specific (4SCAR-GD2) T cells for treatment refractory and/or recurrent neuroblastoma (NB) in pediatric patients. Experimental design A phase I clinical using 4SCAR-GD2 NB patients was conducted. registered at www.clinicaltrials.gov (NCT02765243). lentiviral CAR with signaling domains CD28/4-1BB/CD3ζ-iCasp9 transduced into activated cells. The response T-cell...
Abstract Redox imbalance, including excessive production of reactive oxygen species (ROS) caused by mitochondrial dysfunction and insufficient endogenous antioxidant capacity, is the primary cause myocardial ischemia‒reperfusion (I/R) injury. In exploration reducing I/R injury, it found that protecting function after reperfusion not only reduces ROS bursts but also inhibits cell apoptosis triggered release cytochrome c. Additionally, nuclear factor erythroid 2‐related 2 (Nrf2) considered a...
Dendrocalamus latiflorus is widely distributed in southern China and has high ornamental edible value. The growth dynamics the associations between distribution of nutrients or chemical components across various parts stages shoot development remain inadequately understood. In this study, tender shoots D. from Guangxi, China, were used to conduct experiments. During period, height, ground diameter, morphology investigated, classified by conducting ordered sample cluster analysis. internal...
Abstract It is challenging to construct high‐performing excimer‐based luminescent analytic tools at low molecular concentrations. We report that enzyme‐instructed self‐assembly (EISA) enables the monomer–excimer transition of a coumarin dye ( Cou ) concentrations, and resulting higher ordered supramolecular assemblies (i.e., nanofibers) efficiently record spatiotemporal details alkaline phosphatase (ALP) activity in vitro vivo. was conjugated short peptides with hydrophilic ALP‐responsive...
Abstract PurposeThis study aimed to evaluate the safety and efficacy of fourth-generation chimeric antigen receptor (CAR) disialoganglioside 2 (GD2)-specific (4SCAR-GD2) T cells for treatment refractory and/or recurrent neuroblastoma (NB) in pediatric patients. Experimental DesignA phase I clinical using 4SCAR-GD2 NB patients was conducted. This registered at www.clinicaltrials.gov (NCT02765243). A lentiviral CAR with signaling domains CD28/4-1BB /CD3ζ-iCasp9 transduced into activated...
Although invasive mycosis is a common complication of hematologic malignancies, Fusarium infection, especially systemic disseminated infection rare, which has high mortality due to remarkable intrinsic drug resistance. We reported case 5-year-old high-risk acute lymphocytic leukemia (ALL) female patient complicated with solani during the course chemotherapy. After diagnosis ALL, was treated according South China Children's Leukemia Group-ALL-2016 protocol, and achieved molecular complete...
[Abstract] Objective: This study aims to retrospectively review the clinical presentation and treatment outcomes of 19 cases infant acute lymphocytic leukemia (IALL) treated at our institution, summarizing characteristics prognostic factors IALL. Methods: Data from inpatient outpatient electronic medical records IALL patients Pediatric Hematology Department Zhujiang Hospital, Southern Medical University, April 2019 2023 were collected. A total analyzed for their manifestations, biological...