A5103677422- Environmental Toxicology and Ecotoxicology
- RNA modifications and cancer
- Biochemical and Molecular Research
- Big Data Technologies and Applications
- Genomics and Chromatin Dynamics
- Parasites and Host Interactions
- Web Data Mining and Analysis
- Hormonal and reproductive studies
- Ubiquitin and proteasome pathways
- Reproductive biology and impacts on aquatic species
- Pharmacological Effects and Assays
- Data Quality and Management
- Cancer Research and Treatments
- Physiological and biochemical adaptations
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer, Hypoxia, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Neuroendocrine Tumor Research Advances
- Epigenetics and DNA Methylation
- Glutathione Transferases and Polymorphisms
- Alkaline Phosphatase Research Studies
- TGF-β signaling in diseases
- Fibroblast Growth Factor Research
- Lung Cancer Research Studies
- Cancer-related gene regulation
University of South China
2015-2024
Hunan Cancer Hospital
2021
Central South University
2021
Zhejiang University
2013-2015
Zhejiang Marine Fisheries Research Institute
2015
First Affiliated Hospital of Harbin Medical University
2008-2014
Harbin Medical University
2008-2014
The widely used triazole fungicides have the potential to disrupt endocrine system, but little is known of such effects or underlying mechanisms hexaconazole (HEX) and tebuconazole (TEB) in fish. In present study, zebrafish (Danio rerio) embryos were exposed various concentrations HEX (0.625, 1.25 2.5 mg/L) TEB (1, 2 4 from fertilization 120 h post-fertilization (hpf). whole body content thyroid hormone transcription genes hypothalamic-pituitary-thyroid (HPT) axis analyzed. results showed...
Background Transcription factor Pokemon, a central regulation gene of the important tumor suppressor ARF gene, exerted its activity by acting upstream many tumor-suppressing genes and proto-oncogenes. Its expression in non-small cell lung cancer (NSCLC) clinical significance remains unclear. The aim this study was to investigate Pokemon NSCLC explore correlation with pathological characteristics influence on patients' prognosis. Methods Fifty-five cases were involved study. tissue,...
Neuroendocrine differentiation is often found in colorectal cancer but its impact on prognosis remains controversial. This study explored the association between neuroendocrine and stage II/III patients.
Objective To investigate the status and diagnostic value of hypermethylated TMS1/ASC gene promoter in plasma bronchoalveolar lavage fluid (BALF) lung cancer patients.Methods Methylation specific polymerease chain reaction (MSP) was used to detect hypermethylation BALF 92 cases 20 benign lesions.Results The positive rate methylation patients 27.2％ 32.6％ respectively,and not found or with lesions (x2 =6.997,8.908 ; P ＜ 0.05).The expression correlated gender,histopathological type,clinical...
Objective To evaluate the expression of vascular endothelial growth factor(VEGF),basic fibroblast factor(bFGF)and transforming factor betal(TGFβ1)in non-small cell lung cancer (NSCLC)and to investigate its relationship histopathological features.Methods The VEGF,bFGF,TGFβ1 and CD34 were examined in 50 specimens NSCLC 18 para-cancerous tissue by using SP immunohistochemistry staining.Assessment microvessel density(MVD)was performed.Results positive rate was 68%.The VEGF related clinical...