- Periodontal Regeneration and Treatments
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Hematopoietic Stem Cell Transplantation
- Sexual function and dysfunction studies
- Ovarian function and disorders
- Reproductive Health and Technologies
- 3D Printing in Biomedical Research
University of Indonesia
2019-2024
Hematopoietic stem cells (HSCs) are the progenitor for all blood types including leukocytes, erythrocytes and platelets. Normally, human body is programmed to maintain sufficient level of hematopoietic or derivatives. However, in certain conditions, repeated chemotherapy, leukemic cancer, genetic mutation, bone marrow disorders; HSC transplantation becomes necessary. deals with two major obstacles: leukocyte antigen (HLA) matching high cell dose. Non-match activates immune reaction induces...
Abstract Background Hyperandrogenism is frequently found in polycystic ovary syndrome (PCOS) and contributes to physical manifestations like hirsutism obesity, along with infertility. This condition can result anxiety, depression, body image disorders, potentially leading sexual dysfunction. The objective of this investigation was assess the correlation among hirsutism, anthropometric characteristics, dysfunction, anxiety levels infertile Indonesian women diagnosed PCOS. Methods From...
Mesenchymal stem cells (MSCs) is progenitor cell that capable to differentiate various mesenchymal or non-mesenchymal lineages. MSC also play a role towards injury during healing and regeneration processes in most tissue. Platelet rich plasma (PRP) had been reported induce endometrium regeneration, therefore compacted form of PRP, known as platelet fibrin matrix (PRFM), was studied for its capability host the behavior matrix. PRP gelation generated by adding 25 mM CaCl2 coin shape with...
Objective: The platelet-rich fibrin matrix (PRFM) is condensed plasma (PRP) and should possess a comparable biomechanical property to the transplanted sites, for them be physiologically functional. aim of this study was investigate effect human bone marrow mesenchymal stem cells (hBM-MSC) or umbilical cord (hUC-MSC) on properties PRFM.
 Methods: PRFM prepared by gelation PRP using 25 mmol CaCl2. resulting coin-shaped pellets, 5 cm in diameter 300 μm thick, were directly seeded with...