A5114832501- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Pulsars and Gravitational Waves Research
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Occupational and environmental lung diseases
- Congenital Diaphragmatic Hernia Studies
- Maritime Transport Emissions and Efficiency
- Ship Hydrodynamics and Maneuverability
- Bladder and Urothelial Cancer Treatments
- Cancer, Hypoxia, and Metabolism
- Gamma-ray bursts and supernovae
- Water Quality Monitoring Technologies
- Urinary and Genital Oncology Studies
- Health Promotion and Cardiovascular Prevention
- MRI in cancer diagnosis
- Geophysics and Gravity Measurements
- MicroRNA in disease regulation
- Economic and Financial Impacts of Cancer
- Recommender Systems and Techniques
- Circular RNAs in diseases
National Cancer Institute
2012-2025
National Institutes of Health
2002-2025
Sun Yat-sen University
2015-2024
Sixth Affiliated Hospital of Sun Yat-sen University
2015-2024
Henan Normal University
2024
Wuhan University
2024
Nanchang University
2020-2024
Wuhan Asia Heart Hospital
2024
Panzhihua Central Hospital
2024
Panzhihua University
2024
The effect on mortality of screening for lung cancer with modern chest radiographs is unknown.To evaluate the using in Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.Randomized controlled trial that involved 154,901 participants aged 55 through 74 years, 77,445 whom were assigned to annual screenings 77,456 usual care at 1 10 centers across United States between November 1993 July 2001. data from a subset eligible National Lung Trial (NLST), which compared radiograph...
BackgroundCurrent lung cancer screening guidelines use either mean diameter, volume, or density of the largest nodule on previous CT scan appearance a new to ascertain timing next scan. We aimed develop an accurate protocol by estimating 3-year risk after two scans using deep learning radiologists' readings and other universally available clinical information.MethodsA algorithm (referred as DeepLR) was developed data from participants who had received at least up 2 years apart in National...
Background: The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial was initiated in 1992 to examine cause-specific mortality reduction from screening for these four cancers men women. We report lung cancer detection results of the baseline round. Methods: Of 154 942 participants enrolled, who were aged 55–74 years with no history PLCO cancers, 77 465 randomly assigned intervention arm. Current or former smokers never this arm received an initial single-view...
The 5-year overall survival rate of lung cancer patients is approximately 15%. Most are diagnosed with advanced-stage disease and have shorter rates than early-stage disease. Although screening for has the potential to increase early diagnosis, it not been shown reduce mortality rates. In 1993, Prostate, Lung, Colorectal, Ovarian (PLCO) Cancer Screening Trial was initiated specifically determine whether would from PLCO cancers.A total 77 464 participants, aged 55-74 years, were randomly...
Objectives: We developed ultrasound (US) image-based convolutional neural networks (CNNs) to distinguish between tubal-ovarian abscess (TOA) and ovarian endometriosis cyst (OEC). Methods: A total of 202 patients who underwent US scanning confirmed or by pathology were enrolled in retrospective research, which 171 (from January 2014 September 2021) considered the primary cohort (training, validation, internal test sets) 31 2021 December independent cohort. There 68 abscesses 89 OEC, 4 TOA 10...
Abstract This paper explores the design considerations and hurdles encountered by CHinA National CancEr Screening (CHANCES) Trial Tomosynthesis Mammographic Imaging (TMIST), both aimed at advancing cancer screening research. Before population-based programs are launched, it is important to have confidence that potential benefits of process resulting interventions outweigh harms, an ethical imperative because people actively invited into relatively healthy. Large randomized trials provide...
Well-implemented cancer screening strategies can significantly enhance early detection rates, leading to improved treatment outcomes and reduced mortality. However, there remains a paucity of high-quality evidence from developing regions. The CHinA National CancEr Screening (CHANCES) Trial aims comprehensively evaluate compare different for lung colorectal (CRC) in the Chinese population. CHANCES trial is randomized controlled aimed at assessing effectiveness using low-dose computed...
SUMMARY The lack of statistical theory for the planning early detection trials has resulted in current being sub-optimal. We develop probability models that address three characteristics trials: (i) optimal time analysis and length follow-up, (ii) spacing between examinations, (iii) where numbers examinations versus sample size are balanced fixed costs. optimisation criterion is to maximise power test comparing mortality. Application made breast cancer trials.
Determining whether screening with multicancer detection (MCD) tests saves lives requires randomized controlled trials (RCTs). To inform RCT design, we estimated cancer-mortality outcomes from hypothetical MCD RCTs.
Abstract Background: Some non–small cell lung cancers (NSCLC) progress to distant lymph nodes or metastasize while relatively small. Such small aggressive NSCLCs (SA-NSCLC) are no longer resectable with curative intent, carry a grave prognosis, and may involve unique biological pathways. This is study of factors associated SA-NSCLC. Methods: A nested case-case was embedded in the National Cancer Institute's Prostate, Lung, Colorectal Ovarian Screening Trial. SA-NSCLC cases had stage T1, N3,...
ConclusionWe have shown that an a priori scatter correction algorithm for CB projections improves CBCT image quality on both photon-and proton therapy gantries, potentially opening CBCT-based image/dose-guided therapy.
Abstract Background A small proportion of non–small cell lung cancers (NSCLCs) have been observed to spread distant lymph nodes (N3) or metastasize (M1) both, while the primary tumor is (≤3 cm, T1). These aggressive NSCLCs (SA-NSLSC) are important as they clinically significant, may identify unique biologic pathways, and warrant follow-up treatment. This study identifies factors associated with SA-NSCLC attempts validate a previous finding that women family history cancer at particularly...