A5069883937- Neonatal Respiratory Health Research
- MicroRNA in disease regulation
- Hepatocellular Carcinoma Treatment and Prognosis
- Fibroblast Growth Factor Research
- interferon and immune responses
- Cassava research and cyanide
- RNA modifications and cancer
- Anaerobic Digestion and Biogas Production
- Hedgehog Signaling Pathway Studies
- Kruppel-like factors research
- Wound Healing and Treatments
- Polyamine Metabolism and Applications
- Cancer-related molecular mechanisms research
- Dermatologic Treatments and Research
Wenzhou Medical University
2023-2024
Fourth Hospital of Hebei Medical University
2023
Second Hospital of Shandong University
2023
Hebei Medical University
2023
Abstract Background Acute lung injury (ALI) is a devastating clinical disorder with high mortality rate, and there an urgent need for more effective therapies. Fibroblast growth factor 18 (FGF18) has potent anti-inflammatory properties therefore become focus of research the treatment injury. However, precise role FGF18 in pathological process ALI underlying mechanisms have not been fully elucidated. Methods A mouse model human umbilical vein endothelial cells (HUVEC) stimulated...
Abstract Diabetes is a chronic disease characterized by perturbed glucose and lipid metabolism, resulting in high blood levels. Many complications induced endothelial dysfunction can cause disability even death of diabetic patients. Here, we found that the protein level casein kinase 2α (CK2α) was increased endothelium mice with type I diabetes (T1D) streptozotocin (STZ) injection. Although potential correlation between CK2α established, contribution to progression remained largely unknown....
Abstract Background: Bronchopulmonary dysplasia (BPD) is a complex disorder resulting from interactions between genes and the environment. The precise molecular etiology of BPD remains unclear. This study aimed to determine potential biomarkers possible therapeutic targets through competitive endogenous RNA (ceRNA) network analysis lay foundation for future clinical research. Methods : First, we downloaded mRNA, miRNA, long non-coding (lncRNA) expression profiles patients with Comprehensive...
Background: Inflammatory cytokines are related to the occurrence and development of hepatocellular carcinoma (HCC). Objectives: Interleukin 6 (IL-6) is associated with prognosis HCC, while Dicer inhibits HCC; accordingly, we checked whether regulates HCC by modulating IL-6 pathway. Methods: The cells SMMC-7721 transfected overexpression (pCMV-Dicer) control (pCMV-NC) lentivirus were divided into 3 groups: SMMC-7721, pCMV-NC, pCMV-Dicer groups. assays cell proliferation, migration, invasion...