Shilei Zhang

ORCID: 0009-0001-8964-5264
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Leptospirosis research and findings
  • Drug-Induced Hepatotoxicity and Protection
  • Viral Infections and Immunology Research
  • Vector-Borne Animal Diseases
  • Animal Disease Management and Epidemiology
  • Pharmacological Effects of Natural Compounds
  • Traditional Chinese Medicine Analysis
  • Healthcare professionals’ stress and burnout
  • Health and Well-being Studies
  • Neurological Disorders and Treatments
  • Clostridium difficile and Clostridium perfringens research
  • Analytical Chemistry and Chromatography
  • Viral Infections and Vectors
  • Innovations in Medical Education
  • Safety and Risk Management
  • Mycobacterium research and diagnosis
  • Crystallography and molecular interactions

Shihezi University
2025

Lanzhou Veterinary Research Institute
2024-2025

Chinese Academy of Agricultural Sciences
2024-2025

Lanzhou University
2024-2025

Jilin University
2021-2024

Xinjiang Medical University
2016-2017

African swine fever, one of the major viral diseases swine, poses an imminent threat to global pig industry. The high-efficient replication causative agent fever virus (ASFV) in various organs pigs greatly contributes disease. However, how ASFV manipulates cell population drive vivo remains unclear. Here, we found that spleen reveals most severe pathological manifestation with highest loads among during infection. By using single-cell-RNA-sequencing technology and multiple methods,...

10.1073/pnas.2312150121 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2024-02-27

Nymphaea candida was used to treat hepatitis in Ugyhur medicine, and nicotiflorin (kaempferol 3-O-β-rutinoside) is the main characteristic component this plant [...].

10.3390/ijms18030587 article EN cc-by International Journal of Molecular Sciences 2017-03-08

Leptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp. Humans and some mammals can develop severe forms of leptospirosis accompanied a dysregulated inflammatory response, which often results in death. The gut microbiota has been increasingly recognized as vital element systemic health. However, the precise role still unknown. Here, we aimed to explore function potential mechanisms hamster model leptospirosis. Our study showed that leptospires were able multiply...

10.7554/elife.96065.3 article EN cc-by eLife 2024-05-31

To investigate the prevalence and pathogenic characteristics of avian reovirus (ARV) in Xinjiang region China, this study collected suspected joint tissue samples from broiler farms across different areas Taikun Group. The were subjected to virus isolation, RT-PCR analysis, sequence vitro replication assays, pathogenicity assessments specific pathogen-free (SPF) chicken embryos chickens. results revealed isolation a chicken-derived ARV epidemic strain, designated as xj-1.1. virus-induced...

10.3390/v17040499 article EN cc-by Viruses 2025-03-30

Leptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp. Humans and some mammals can develop severe forms of leptospirosis accompanied a dysregulated inflammatory response, which often results in death. The gut microbiota has been increasingly recognized as vital element systemic health. However, the precise role still unknown. Here, we aimed to explore function potential mechanisms hamster model leptospirosis. Our study showed that leptospires were able multiply...

10.7554/elife.96065.2 preprint EN 2024-05-20

Objective To explore the status of residents′ knowledge, attitude and behavior on first aid in Lucky Community Urumqi, Xinjiang, so as to provide scientific basis for effective knowledge popularization among urban community residents. Methods Totals 399 residents were selected by cluster random sampling surveyed self-designed questionnaires about their attitude, on-site aid. Results 30.00% did not call emergency number when they encountered an accident; more than 50.00% know...

10.3760/cma.j.issn.1674-2907.2016.23.016 article EN Zhonghua xiandai huli zazhi 2016-08-16
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